Spontaneous tumor cytolysis mediated by inflammatory neutrophils: dependence upon divalent cations and reduced oxygen intermediates

H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.

1975 • 653 citations

H2O2 Release from Human Granulocytes during Phagocytosis

1977 • 586 citations

Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity.

1979 • 538 citations

Neutrophil-mediated tumor cell cytotoxicity: role of the peroxidase system.

1975 • 317 citations

Stimulation of neutrophil oxidative metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate

1979 • 259 citations

Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.

1983 • 225 citations

The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils

1981 • 205 citations

Characterization of the cytolytic reaction mechanism of the human natural killer (NK) lymphocyte: resolution into binding, programming, and killer cell-independent steps.

1982 • 177 citations

Superoxide Production by Digitonin-Stimulated Guinea Pig Granulocytes

1978 • 177 citations

Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process.

1979 • 170 citations

Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells

1975 • 169 citations

Exposure of human neutrophils to chemotactic factors potentiates activation of the respiratory burst enzyme.

1983 • 157 citations

The role of superoxide in the destruction of erythrocyte targets by human neutrophils.

1980 • 156 citations

NATURE OF LYMPHOCYTE-TUMOR INTERACTION

1973 • 136 citations

Interaction between human neutrophils and zymosan particles: the role of opsonins and divalent cations.

1981 • 128 citations

The myeloperoxidase-hydrogen peroxide-halide system as effector of neutrophil-mediated tumor cell cytotoxicity.

1981 • 116 citations

PEROXIDASE-MEDIATED MAMMALIAN CELL CYTOTOXICITY

1973 • 109 citations

An oxygen-dependent mechanism of neutrophil-mediated cytotoxicity

1980 • 95 citations

A potential role for hypochlorous acid in granulocyte-mediated tumor cell cytotoxicity

1980 • 95 citations

Enhancement of chemotactic factor-stimulated neutrophil oxidative metabolism by leukotriene B4

1984 • 82 citations

Studies on a transplantable teratoma of the mouse.

1952 • 77 citations

Anti‐tumor effect of inelammatory neutrophils: Characteristics of in vivo generation and in vitro tumor cell lysis

1985 • 73 citations

Human monocyte-mediated tumor cytotoxicity. I. Demonstration of an oxygen-dependent myeloperoxidase-independent mechanism.

1984 • 62 citations

Successful immunotherapy with intraperitoneal Corynebacterium parvum in a murine ovarian cancer model is associated with the recruitment of tumor-lytic neutrophils into the peritoneal cavity.

1984 • 42 citations

Evidence for the role of superoxide radicals in neutrophil-mediated cytotoxicity.

1979 • 37 citations

The binding of tumor cells by murine mononuclear phagocytes can be divided into two qualitatively distinct types.

1983 • 36 citations

Mechanisms of tumour cell destruction by PMA-activated human neutrophils.

1983 • 34 citations

Studies of the induction and expression of T cell mediated immunity. VI. Heterogeneity of lytic efficiency exhibited by isolated cytotoxic T lymphocytes prepared from highly enriched populations of effector-target conjugates.

1977 • 34 citations

Role of oxygen in T cell-mediated cytolysis.

1982 • 32 citations

Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity.

1983 • 28 citations

Regulation of monocyte oxidative metabolism: chemotactic factor enhancement of superoxide release, hydroxyl radical generation, and chemiluminescence.

1983 • 15 citations

Use of a self-generating percoll gradient and single cell cytotoxicity assay to identify tumor-lytic properties of inflammatory neutrophils

1985 • 7 citations