Variable opacity (Opa) outer membrane proteins account for the cell tropisms displayed by Neisseria gonorrhoeae for human leukocytes and epithelial cells.

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Fast and sensitive multiple sequence alignments on a microcomputer

1989 • 1,245 citations

Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli

1988 • 1,049 citations

Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells

1987 • 599 citations

Opacity genes in Neisseria gonorrhoeae: Control of phase and antigenic variation

1986 • 428 citations

Pilus expression in neisseria gonorrhoeae involves chromosomal rearrangement

1982 • 332 citations

Discrimination Between Intracellular Uptake and Surface Adhesion of Bacterial Pathogens

1991 • 302 citations

Pilus genes of Neisseria gonorrheae: chromosomal organization and DNA sequence.

1984 • 298 citations

Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assembly.

1991 • 292 citations

Pathogenic Mechanisms of Neisseria gonorrhoeae: Observations on Damage to Human Fallopian Tubes in Organ Culture by Gonococci of Colony Type 1 or Type 4

1981 • 250 citations

Phase variation of the opacity outer membrane protein controls invasion by Neisseria gonorrhoeae into human epithelial cells.

1991 • 225 citations

The role of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells

1991 • 202 citations

Interaction of two variable proteins (PilE and PilC) required for pilus‐mediated adherence of Neisseria gonorrhoeae to human epithelial cells

1992 • 199 citations

Phase variation of gonococcal protein II: Regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence

1989 • 198 citations

Role of lipopolysaccharide and outer membrane protein of Escherichia coli K-12 in the receptor activity for bacteriophage T4

1978 • 180 citations

The Human Fallopian Tube: A Laboratory Model for Gonococcal Infection

1974 • 170 citations

Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by Neisseria meningitidis

1992 • 165 citations

Genetic variation in pathogenic bacteria

1992 • 158 citations

Antigenic and physical diversity of Neisseria gonorrhoeae lipooligosaccharides

1986 • 147 citations

Model for invasion of human tissue culture cells by Neisseria gonorrhoeae

1988 • 135 citations

Opacity determinants of Neisseria gonorrhoeae: Gene expression and chromosomal linkage to the gonococcal pilus gene

1984 • 131 citations

Roles of lipopolysaccharide and outer membrane protein OmpC of Escherichia coli K-12 in the receptor function for bacteriophage T4

1982 • 127 citations

The Effect of Protein II and Pili on the Interaction of Neisseria gonorrhoeae with Human Polymorphonuclear Leucocytes

1986 • 122 citations

Studies on gonococcus infection. XV. Identification of surface proteins of Neisseria gonorrhoeae correlated with leukocyte association

1978 • 116 citations

Release of soluble pilin antigen coupled with gene conversion in Neisseria gonorrhoeae.

1987 • 115 citations

Recombination among Protein II genes of Neisseria gonorrhoeae generates new coding sequences and increases structural variability in the Protein II family

1988 • 113 citations

In situ expression and localization of Neisseria gonorrhoeae opacity proteins in infected epithelial cells: apparent role of Opa proteins in cellular invasion.

1991 • 112 citations

Gonococci possessing only certain P.II outer membrane proteins interact with human neutrophils

1988 • 104 citations

Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9

1980 • 102 citations

Identification and characterization of a Neisseria gonorrhoeae gene encoding a glycolipid-binding adhesin.

1990 • 87 citations

Further antigenic similarities of Neisseria gonorrhoeae lipooligosaccharides and human glycosphingolipids

1992 • 67 citations

Human neutrophil response to recombinant neisserial Opa proteins

1992 • 67 citations

Physical and genetic map of the Neisseria gonorrhoeae strain MS11‐N198 chromosome

1991 • 58 citations

Escherichia coli expressing a Neisseria gonorrhoeae opacity-associated outer membrane protein invade human cervical and endometrial epithelial cell lines.

1992 • 54 citations

Expression and phase variation of gonococcal P.11 genes in Escherichia coli involves ribosomal frameshifting and slipped‐strand mispairing

1989 • 53 citations

Enhancement of the invasive ability of Neisseria gonorrhoeae by contact with HeclB, an adeno‐carcinoma endometrial cell line

1991 • 51 citations

Interactions of Neisseria gonorrhoeae with human neutrophils

1989 • 41 citations

Erythrocyte gangliosides act as receptors for Neisseria subflava: identification of the Sia-1 adhesin

1990 • 37 citations

The Pathogenesis of Bacterial Infections

1985 • 34 citations

Three copies of a single protein II‐encoding sequence in the genome of Neisseria gonorrhoeae JS3: evidence for gene conversion and gene duplication

1988 • 30 citations

A Determinant of Resistance of Neisseria gonorrhoeae to Killing by Human Phagocytes: an Outer Membrane Lipoprotein of about 20 kDa with a High Content of Glutamic Acid

1986 • 20 citations

Expression of gonococcal protein II in Escherichia coli by translational fusion

1989 • 19 citations

Purification and immunological studies of the cross-reaction between the 65-kilodalton gonococcal parietal lectin and an antigen common to a wide range of bacteria

1992 • 14 citations

Ultrastructural localization of gonococcal antigens in infected epithelial cells as visualized by post-embedding immuno-electronmicroscopy

1988 • 13 citations

Surface proteins of pathogenic "Neisseria": antigenic variation and conserved epitopes.

1986 • 8 citations