Inherited Disorders of the Red Cell Membrane Skeleton

THE ORGANIZATION OF PROTEINS IN THE HUMAN RED BLOOD CELL MEMBRANE

1974 • 1,554 citations

Membrane Asymmetry

1977 • 965 citations

Selective solubilization of proteins and phospholipids from red blood cell membranes by nonionic detergents

1973 • 687 citations

The molecular structure of human erythrocyte spectrin

1979 • 539 citations

The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes

1979 • 423 citations

Post splenectomy sepsis

1973 • 393 citations

Hazard of Overwhelming Infection after Splenectomy in Childhood

1967 • 377 citations

Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin

1979 • 355 citations

Spectrin as a stabilizer of the phospholipid asymmetry in the human erythrocyte membrane

1978 • 346 citations

ANIONIC SITES OF HUMAN ERYTHROCYTE MEMBRANES

1973 • 307 citations

Purification of two spectrin-binding proteins: biochemical and electron microscopic evidence for site-specific reassociation between spectrin and bands 2.1 and 4.1.

1979 • 286 citations

In vitro formation of a complex between cytoskeletal proteins of the human erythrocyte

1979 • 254 citations

On the mechanism of ATP-induced shape changes in human erythrocyte membranes. I. The role of the spectrin complex.

1977 • 248 citations

Spectrin-actin membrane skeleton of normal and abnormal red blood cells.

1979 • 244 citations

Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells.

1976 • 214 citations

Dissecting the red cell membrane skeleton

1979 • 212 citations

Pneumococcal Polysaccharide Immunization in Infants and Children

1978 • 208 citations

Hematology of Infancy and Childhood

1981 • 206 citations

REPAIR OF SKIN DEFECTS

1947 • 195 citations

Selective alteration of erythrocyte deformability by SH-reagents. Evidence for an involvement of spectrin in membrane shear elasticity

1978 • 175 citations

CONGENITAL HEMOLYTIC JAUNDICE. THE PATHOGENESIS OF THE "HEMOLYTIC CRISIS"

1948 • 172 citations

Increased Cell Membrane Permeability in the Pathogenesis of Hereditary Spherocytosis *

1964 • 169 citations

Relation Between Splenectomy and Subsequent Infection: A Clinical Study

1962 • 167 citations

Integral membrane protein interaction with triton cytoskeletons of erythrocytes

1979 • 165 citations

Red-Cell Antibodies in Acquired Hemolytic Anemia with Negative Antiglobulin Serum Tests

1971 • 149 citations

Lateral mobility of human erythrocyte integral membrane proteins

1977 • 145 citations

Intra- and intermolecular cross-linking of membrane proteins in intact erythrocytes and ghosts by SH-oxidizing agents

1977 • 133 citations

A Congenital Haemolytic Anaemia with Thermal Sensitivity of the Erythrocyte Membrane

1975 • 121 citations

Hereditary Spherocytosis

1951 • 115 citations

Spectrin/actin complex isolated from sheep erythrocytes accelerates actin polymerization by simple nucleation. Evidence for oligomeric actin in the erythrocyte cytoskeleton.

1980 • 110 citations

Selective Depression of Blood Group Antigens Associated with Hereditary Ovalocytosis among Melanesians

1977 • 103 citations

Studies on the Destruction of Red Blood Cells

1956 • 102 citations

The role of membrane lipids in the survival of red cells in hereditary spherocytosis

1969 • 100 citations

A Scanning Electron Microscopic Study of the Spleen

1974 • 100 citations

Appearance and distribution of surface proteins of the human erythrocyte membrane. An electron microscope and immunochemical labeling study.

1978 • 97 citations

Control of interaction of spectrin and actin by phosphorylation

1977 • 96 citations

Studies on Spontaneous In Vitro Autohemolysis in Hemolytic Disorders

1956 • 96 citations

Clustering and endocytosis of membrane receptors can be induced in mature erythrocytes of neonatal but not adult humans.

1976 • 95 citations

Genetics of spherocytosis.

1962 • 91 citations

Dependence of spectrin organization in red blood cell membranes on cell metabolism: implications for control of red cell shape, deformability, and surface area.

1979 • 86 citations

Malaria and hereditary ovalocytosis

1977 • 83 citations

Membrane protein phosphorylation of intact normal and hereditary spherocytic erythrocytes.

1978 • 83 citations

Incidence of Gallbladder Disease in Chronic Hemolytic Anemia (Spherocytosis)

1952 • 78 citations

Hereditary Spherocytosis

1951 • 77 citations

Abnormal membrane protein of red blood cells in hereditary spherocytosis

1971 • 74 citations

The selective and conjoint loss of red cell lipids

1969 • 73 citations

Domains of receptor mobility and endocytosis in the membranes of neonatal human erythrocytes in the membranes of neonatal human erythrocytes and reticulocytes are deficient in spectrin

1979 • 67 citations

Diminished spectrin extraction from ATP-depleted human erythrocytes. Evidence relating spectrin to changes in erythrocyte shape and deformability.

1978 • 66 citations

HEREDITARY SPHEROCYTOSIS WITH SECONDARY HÆMOCHROMATOSIS

1968 • 64 citations

Elliptocytosis with hemolytic anemia: the effects of splenectomy.

1955 • 57 citations

Abnormality in a specific protein of the erythrocyte membrane in hereditary spherocytosis

1974 • 57 citations

Reconstitution of spectrin-deficient, spherocytic mouse erythrocyte membranes.

1979 • 56 citations

Extramedullary Hematopoiesis in Anemias

1928 • 55 citations

ALTERATIONS IN OSMOTIC AND MECHANICAL FRAGILITY RELATED TO IN VIVO ERYTHROCYTE AGING AND SPLENIC SEQUESTRATION IN HEREDITARY SPHEROCYTOSIS*†

1960 • 53 citations

ELLIPTIC ERYTHROCYTES IN MAN

1941 • 51 citations

Red cell life span after splenectomy in hereditary spherocytosis

1968 • 50 citations

Phosphorylation in erythrocyte membranes from abnormally shaped cells

1976 • 49 citations

The Life Span of the Elliptocyte

1954 • 46 citations

Massive Thoracic Extramedullary Hemopoiesis

1960 • 46 citations

Participation of spectrin in Sendai virus-induced fusion of human erythrocyte ghosts.

1978 • 46 citations

The hereditary elliptocytoses: clinical and linkage data

1962 • 42 citations

Membrane polypeptide aggregates in glucose 6-phosphate dehydrogenase-deficient and in vitro aged red blood cells.

1978 • 41 citations

Red cell survival studies in hereditary spherocytosis

1970 • 40 citations

Fine Structure of the Red Pulp of the Spleen in Hereditary Spherocytosis

1972 • 40 citations

Congenital Spherocytosis in Infancy

1958 • 39 citations

Heat‐Induced Erythrocyte Fragmentation in Neonatal Elliptocytosis

1979 • 39 citations

Hereditary Spherocytosis: Observations on Hemolytic Mechanisms and Iron Metabolism

1960 • 38 citations

Fatty Acid Composition of Erythrocytes in Hereditary Spherocytosis

1979 • 37 citations

ASCERTAINING GENETIC CARRIERS OF HEREDITARY SPHEROCYTOSIS BY STATISTICAL ANALYSIS OF MULTIPLE LABORATORY TESTS*

1962 • 36 citations

Congenital Hemolytic Anemia in the Newborn

1957 • 36 citations

HEREDITARY ELLIPTOCYTOSIS: AN UNUSUAL PRESENTATION OF HEMOLYSIS IN THE NEWBORN ASSOCIATED WITH TRANSIENT MORPHOLOGIC ABNORMALITIES

1969 • 35 citations

Association of decreased membrane protein phosphorylation with red blood cell spherocytosis

1977 • 34 citations

Red cell calcium leak in congenital hemolytic anemia with extreme microcytosis

1976 • 33 citations

Fragmentation and myelin formation in hereditary xerocytosis and other hemolytic anemias

1978 • 33 citations

A New Familial Disorder with Abnormal Erythrocyte Morphology and Increased Permeability of the Erythrocytes to Sodium and Potassium

1971 • 31 citations

Hereditary spherocytosis in 100 children.

1966 • 31 citations

Autosomal dominant hemolytic anemia characterized by ovalocytosis

1965 • 30 citations

Differences in fatty acid composition between normal human erythrocytes and hereditary spherocytosis affected cells

1972 • 30 citations

Neonatal Manifestations of Hereditary Spherocytosis

1967 • 28 citations

Relative deficiency of Ca2+-dependent adenosine triphosphatase activity of red cell membranes in hereditary spherocytosis

1974 • 28 citations

Spinal cord disease in hereditary spherocytosis: report of two cases with a hypothesized common mechanism for neurologic and red cell abnormalities

1976 • 26 citations

Spectrin rearrangement early in erythrocyte ghost endocytosis.

1979 • 26 citations

Atypical Autohemolysis in Hereditary Spherocytosis as a Reflection of Two Cell Populations: Relationship of Cell Lipids to Conditioning by the Spleen

1968 • 26 citations

Increased Erythrocyte Ca2+ Content in Hereditary Spherocytosis

1975 • 25 citations

CONGENITAL AND FAMILIAL HEMOLYTIC DISEASE IN CHILDREN

1938 • 25 citations

Absence of one component of spectrin adenosine triphosphatase in hereditary spherocytosis

1975 • 25 citations

Involvement of spectrin in membrane fusion: induction of fusion in human erythrocyte ghosts by proteolytic enzymes and its inhibition by antispectrin antibody.

1979 • 24 citations

Erythrocyte Membrane Elasticity, Fragmentation and Lysis

1978 • 23 citations

Muscle G-actin is an inhibitor of ATP-induced erythrocyte ghost shape changes and endocytosis

1977 • 22 citations

Comparison of structure and function of human erythrocyte and human muscle actin.

1979 • 22 citations

Hereditary elliptocytosis with hemolytic anemia

1963 • 22 citations

Monoclonal Gammopathy in Hereditary Spherocytosis: A Possible Pathogenetic Relation

1978 • 20 citations

HEREDITARY SPHEROCYTOSIS: A DISEASE OF THE RED CELL MEMBRANE.

1965 • 20 citations

Hereditary Spherocytosis: The Metabolism of Erythrocytes in the Peripheral Blood and in the Splenic Pulp

1974 • 19 citations

Pyknocytosis in a Neonate: An Unusual Presentation of Hereditary Elliptocytosis

1977 • 18 citations

Hereditary Haemolytic Anaemia associated with Elliptocytosis: a Study of Three Families

1961 • 16 citations

Abnormal binding of spectrin to the membrane of erythrocytes in some cases of hereditary spherocytosis

1978 • 16 citations

Homozygous Hereditary Elliptocytosis as the Cause of Haemolytic Anemia in Infancy

1968 • 16 citations

Serum Haptoglobin in Infancy

1961 • 16 citations

CHRONIC ULCER OF THE LEG ASSOCIATED WITH CONGENITAL HEMOLYTIC JAUNDICE

1939 • 15 citations

Hereditary Spherocytosis

1965 • 15 citations

Hereditary Elliptocytosis in Iceland

1967 • 15 citations

Sporadic Congenital Spherocytosis Associated with Congenital Hypoplastic Thrombocytopenia and Malformations

1958 • 15 citations

Haemolytic Anaemia in Infectious Mononucleosis Due to Inapparent Congenital Spherocytosis

1970 • 14 citations

Haemolysis in Athletes due to Hereditary Spherocytosis

1979 • 14 citations

Effect of adrenal steroids in hereditary spherocytic anemia.

1956 • 14 citations

Studies on Calcium Transport and Calcium‐dependent Adenosine Triphosphatase Activity of Erythrocyte Membranes in Hereditary Spherocytosis

1976 • 13 citations

Hereditary elliptocytosis and hyperhaemolysis. A comparative study of 6 families with 145 patients.

1966 • 13 citations

HEREDITARY ELLIPTOCYTOSIS ASSOCIATED WITH INCREASED HEMOLYSIS

1955 • 12 citations

Hereditary Elliptocytosis and Hyperhaemolysis

1966 • 12 citations

Recurrent Hemolytic Anemia Secondary to Accessory Spleens

1978 • 12 citations

Variations of the Mean Diameter in the Ripening of the Erythrocyte.

1950 • 11 citations

Hereditary elliptocytic anaemia

1961 • 10 citations

The surgical treatment of hereditary spherocytosis.

1974 • 9 citations

Altered Erythrocyte Membrane Protein Phosphorylation in an Unusual Case of Hereditary Spherocytosis

1979 • 9 citations

Hereditary elliptical stomatocytosis: A case report

1976 • 8 citations

The Genetic Basis of Hereditary Elliptocytosis With Hemolysis

1968 • 7 citations

Hereditary Haemolytic Ovalocytosis with Defective Erythropoiesis

1979 • 7 citations

THE ROLE OF SPECTRIN AND ACTIN IN IRREVERSIBLY SICKLED CELLS: UNSICKLING OF “IRREVERSIBLY” SICKLED GHOSTS BY CONDITIONS WHICH INTERFERE WITH SPECTRIN-ACTIN POLYMERIZATION11These studies were supported by research grants HL-15963 and HL-15157 and contract no. HB-4–2973 from the National Institutes of Health. The work was done during the tenure of an Established Investigatorship of the American Heart Association (Dr. Lux).

1978 • 7 citations

An unusual variant of hereditary spherocytosis

1970 • 7 citations

Splenectomy in congenital microspherocytosis

1969 • 7 citations

Atypical Hereditary Spherocytosis: Biochemical Studies and Sites of Erythrocyte Destruction

1967 • 6 citations

Hereditary elliptocytosis with hemolytic anemia--a family study of five affected members.

1969 • 6 citations

Erythrocyte membrane proteins in hereditary glucosephosphate isomerase deficiency.

1979 • 5 citations

Red pulp of the spleen in hereditary elliptocytosis

1977 • 4 citations