Jasplakinolide: An Actin-Specific Reagent that Promotes Actin Polymerization

High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A

1997 • 734 citations

Phosphatidylinositol 4,5-Bisphosphate Functions as a Second Messenger that Regulates Cytoskeleton–Plasma Membrane Adhesion

2000 • 651 citations

Effects of Jasplakinolide on the Kinetics of Actin Polymerization

2000 • 504 citations

Jasplakinolide, a cyclodepsipeptide from the marine sponge, SP.

1986 • 304 citations

Cytochalasin inhibits the rate of elongation of actin filament fragments

1979 • 295 citations

Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity

1986 • 280 citations

Myosin-II-Dependent Localization and Dynamics of F-Actin during Cytokinesis

2005 • 278 citations

Actin-targeting natural products: structures, properties and mechanisms of action

2006 • 193 citations

Entry of the Two Infectious Forms of Vaccinia Virus at the Plasma Membane Is Signaling-Dependent for the IMV but Not the EEV

2000 • 180 citations

Actin depolymerization is sufficient to induce programmed cell death in self-incompatible pollen

2006 • 154 citations

Jasplakinolide's Inhibition of the Growth of Prostate Carcinoma Cells In Vitro With Disruption of the Actin Cytoskeleton

1995 • 152 citations

Actin Stabilization by Jasplakinolide Enhances Apoptosis Induced by Cytokine Deprivation

1999 • 141 citations

Jasplakinolide Induces Apoptosis in Various Transformed Cell Lines by a Caspase-3-Like Protease-Dependent Pathway

2000 • 139 citations

Clustering of Membrane Raft Proteins by the Actin Cytoskeleton

2007 • 125 citations

Initiation of Apoptosis by Actin Cytoskeletal Derangement in Human Airway Epithelial Cells

2001 • 120 citations

Fluid-Phase Markers in the Basolateral Endocytic Pathway Accumulate in Response to the Actin Assembly-promoting Drug Jasplakinolide

1998 • 104 citations

Induction of an acrosomal process in Toxoplasma gondii : Visualization of actin filaments in a protozoan parasite

1999 • 100 citations

New class of antifungal agents: jasplakinolide, a cyclodepsipeptide from the marine sponge, Jaspis species

1988 • 90 citations

ADF/cofilin family proteins control formation of oriented actin-filament bundles in the cell body to trigger fibroblast polarization

2007 • 89 citations

Actin polymerization promotes the reversal of streaming in the apex of pollen tubes

2005 • 89 citations

Effects of F-actin stabilization or disassembly on epithelial Cl- secretion and Na-K-2Cl cotransport

1997 • 87 citations

Asymmetric total synthesis of (+)-jasplakinolide

1991 • 86 citations

A novel structure involved in the formation of liver endothelial cell fenestrae revealed by using the actin inhibitor misakinolide

1998 • 84 citations

Formation of F-actin aggregates in cells treated with actin stabilizing drugs

1998 • 82 citations

Micrasterias cells as a model system for research on morphogenesis

1993 • 79 citations

Microfilament stabilization by jasplakinolide arrests oocyte maturation, cortical granule exocytosis, sperm incorporation cone resorption, and cell-cycle progression, but not DNA replication, during fertilization in mice

2000 • 73 citations

Vesicle production and fusion during lobe formation inMicrasterias visualized by high-pressure freeze fixation

1992 • 73 citations

Actin Polymerisation Regulates Integrin-Mediated Adhesion as Well as Rigidity of Neutrophils

1997 • 71 citations

Actin filaments are involved in the maintenance of Golgi cisternae morphology and intra‐Golgi pH

2006 • 70 citations

A simple model for the cooperative stabilisation of actin filaments by phalloidin and jasplakinolide

2004 • 69 citations

Jaspamide from the Marine Sponge Jaspis johnstoni

1987 • 67 citations

Jasplakinolide, a novel actin targeting peptide, inhibits cell growth and induces actin filament polymerization in the green algaMicrasterias

1997 • 66 citations

Novel marine sponge-derived amino acids. 8. Conformational analysis of jasplakinolide

1989 • 58 citations

Microtubules facilitate the stimulated secretion of β-hexosaminidase in lacrimal acinar cells

1998 • 52 citations

motility and host cell invasiveness are drastically impaired by jasplakinolide, a cyclic peptide stabilizing F-actin

1999 • 52 citations

Enantioselective Total Synthesis of (+)-Jasplakinolide

2007 • 51 citations

In vitro screening of crude extracts and pure metabolites obtained from marine invertebrates for the treatment of breast cancer

1992 • 50 citations

Polarity establishment requires dynamic actin in fucoid zygotes

2003 • 50 citations

Participation of Host Cell Actin Filaments during Interaction of Trypomastigote Forms of Trypanosoma cruzi with Host Cells.

2002 • 49 citations

Actin cytoskeleton modulates calcium signaling during maturation of starfish oocytes

2008 • 49 citations

Actin cytoskeleton derangement induces apoptosis in renal ischemia/reperfusion

2006 • 47 citations

Variable actin dynamics requirement for the exit of different cargo from the trans‐Golgi network

2007 • 45 citations

Jasplakinolide: interaction with radiation and hyperthermia in human prostate carcinoma and Lewis lung carcinoma

1998 • 37 citations

Effects of temperature on cytomorphogenesis and ultrastructure ofMicrasterias denticulata Br�b

1990 • 35 citations

The anti-proliferative agent jasplakinolide rearranges the actin cytoskeleton of plant cells

1999 • 33 citations

Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament

2007 • 32 citations

Actin Disruption Inhibits Bombesin Stimulation of Focal Adhesion Kinase (pp125FAK) in Prostate Carcinoma

1996 • 32 citations

Jasplakinolide reversibly disrupts actin filaments in suspension-cultured tobacco BY-2 cells

2002 • 32 citations

SPECTRIN‐LIKE PROTEINS IN GREEN ALGAE (DESMIDIACEAE)

1999 • 30 citations

Geographic Variation in the Tropical Marine Sponge Jaspis cf. johnstoni: An Unexpected Source of New Terpene-Benzenoids

1997 • 30 citations

Chondramides, novel cyclodepsipeptides from myxobacteria, influence cell development and induce actin filament polymerization in the green algaMicrasterias

2001 • 28 citations

Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide

2008 • 27 citations

Alteration of Actin Organization by Jaspamide Inhibits Ruffling, but not Phagocytosis or Oxidative Burst, in HL-60 Cells and Human Monocytes

1999 • 24 citations

Growth modulation and differentiation of acute myeloid leukemia cells by jaspamide.

1995 • 23 citations

Design and synthesis of nonpeptide mimetics of jaspamide

1991 • 20 citations

Novel marine sponge derived amino acids. 9. Lithium complexation of jasplakinolide

1989 • 13 citations

Jasplakinolide, an actin stabilizing agent, alters anaphase chromosome movements in crane‐fly spermatocytes

2008 • 13 citations

Latrunculin A depolarizes starfish oocytes

2007 • 11 citations

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