The Regulation of Transcription Initiation in Bacteria

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

Nucleotide sequences that signal the initiation of transcription and translation inBacillus subtilis

1982 • 833 citations

THE GENETICS AND REGULATION OF HEAT-SHOCK PROTEINS

1984 • 648 citations

Genetic aspects of bacterial endospore formation

1976 • 608 citations

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

1984 • 593 citations

Genetic Regulation: The Lac Control Region

1975 • 523 citations

Escherichia colipromoter sequences predictin vitroRNA polymerase selectivity

1984 • 492 citations

Sigma factors fromE. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins

1986 • 460 citations

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

1983 • 458 citations

GENETIC CONTROL OF NITROGEN ASSIMILATION IN BACTERIA

1982 • 449 citations

Cascades of sigma factors

1981 • 445 citations

An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression.

1984 • 375 citations

Consensus sequence for Escherichia coli heat shock gene promoters.

1985 • 372 citations

Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: evidence that the ntrA product is a sigma factor.

1985 • 352 citations

Regulation of the Assimilation of Nitrogen Compounds

1978 • 345 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli K-12.

1982 • 322 citations

Rate-limiting steps in RNA chain initiation.

1980 • 308 citations

Positive regulatory gene for temperature-controlled proteins in Escherichia coli

1981 • 268 citations

The nudeotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E. coil K12

1981 • 262 citations

Lac DNA, RNA Polymerase and Cyclic AMP Receptor Protein, Cyclic AMP, Lac Repressor and Inducer are the Essential Elements for Controlled Lac Transcription

1971 • 238 citations

Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter

1984 • 228 citations

Conformational change in the DNA associated with an unusual promoter mutation in a tRNA operon of Salmonella

1984 • 225 citations

Two RNA polymerase sigma factors from Bacillus subtilis discriminate between overlapping promoters for a developmentally regulated gene

1983 • 218 citations

A control element within a structural gene: The gal operon of Escherichia coli

1983 • 206 citations

Pleiotropic deficiency of carbohydrate utilization in an adenyl cyclase deficient mutant of Escherichia coli

1969 • 203 citations

Nucleotide sequence of the heat shock regulatory gene of E. coli suggests its protein product may be a transcription factor

1984 • 198 citations

Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase

1979 • 197 citations

Developmental and genetic regulation of bacillus subtilis genes transcribed by σ28-RNA polymerase

1983 • 195 citations

Defining a bacteriophage T4 late promoter: Absence of a “−35” region

1984 • 192 citations

Overlapping promoters transcribed by bacillus subtilis sigma 55 and sigma 37 RNA polymerase holoenzymes during growth and stationary phases.

1984 • 188 citations

Change in the Template Specificity of RNA Polymerase during Sporulation of Bacillus subtilis

1969 • 184 citations

Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae

1983 • 173 citations

Requirement for an upstream element for optimal transcription of a bacterial tRNA gene

1983 • 163 citations

A sporulation-induced sigma-like regulatory protein from b. subtilis

1981 • 162 citations

A modified RNA polymerase transcribes a cloned gene under sporulation control in Bacillus subtilis

1979 • 160 citations

Heat shock regulatory gene (htpR) of Escherichia coli is required for growth at high temperature but is dispensable at low temperature.

1984 • 159 citations

The molecular topography of rna polymerase-promoter interaction

1979 • 153 citations

The subtilisin E gene of Bacillus subtilis is transcribed from a sigma 37 promoter in vivo.

1984 • 145 citations

Sequence determinants of promoter activity

1982 • 145 citations

Novel RNA polymerase sigma factor from Bacillus subtilis.

1980 • 133 citations

Demonstration of two operator elements in gal: in vitro repressor binding studies.

1984 • 130 citations

A strong sequence homology exists between the major RNA polymerase sigma factors of Bacillus subtilis and Escherichia coli.

1985 • 129 citations

Lytic Mode of Lambda Development

1983 • 127 citations

An electron microscopic comparison of transcription on linear and superhelical DNA

1976 • 127 citations

Nucleotide Sequence of Sporulation Locus spoIIA in Bacillus subtilis

1984 • 125 citations

Specific binding of CAP factor to lac promoter DNA

1975 • 125 citations

Evidence for two sites in the lac promoter region

1972 • 124 citations

Thermodynamic origins of specificity in the lac repressor-operator interaction

1985 • 121 citations

Starting and Stopping Sequences for the RNA Polymerase

1976 • 119 citations

Nitrogen regulation in Salmonella typhimurium. Identification of an ntrC protein-binding site and definition of a consensus binding sequence.

1985 • 116 citations

Tandem promoters determine regulation of theKlebsiella pneumoniaeglutamine synthetase (glnA) gene

1984 • 116 citations

The interaction of bacterial and phage proteins with immobilized Escherichia coli RNA polymerase

1974 • 115 citations

The Location of the Repressor Binding Sites in the lac Operon

1974 • 112 citations

Deletion analysis of a complex promoter for a developmentally regulated gene from Bacillus subtilis

1983 • 111 citations

Isolation of the nitrogen assimilation regulator NR _I , the product of the glnG gene of Escherichia coli

1983 • 104 citations

Promoter for a developmentally regulated gene in Bacillus subtilis

1981 • 103 citations

Cyclic AMP receptor protein interacts with lactose operator DNA

1981 • 103 citations

Bacillus subtilis sigma factor sigma 29 is the product of the sporulation-essential gene spoIIG.

1985 • 97 citations

DNA adenine methylation of GATC sequences appeared recently in the Escherichia coli lineage

1984 • 97 citations

A developmental gene product of Bacillus subtilis homologous to the sigma factor of Escherichia coli

1984 • 95 citations

Developmentally regulated transcription in a cloned segment of the Bacillus subtilis chromosome

1981 • 94 citations

Mutant lambda phage repressor with a specific defect in its positive control function.

1982 • 93 citations

Nucleotide sequences of two Bacillus subtilis promoters used by Bacillus subtilis sigma-28 RNA polymerase

1981 • 90 citations

Mechanism of Initiation of Repression of In Vitro Transcription of the Lac Operon of Escherichia coli

1971 • 90 citations

Defining a bacteriophage T4 late promoter: bacteriophage T4 gene 55 protein suffices for directing late promoter recognition.

1984 • 83 citations

Nucleotide sequence of the early genes 3 and 4 of bacteriophage ø29

1982 • 83 citations

Initiation of in vitro mRNA synthesis from the wild-type lac promoter.

1975 • 82 citations

Synthesis of sigma 29, an RNA polymerase specificity determinant, is a developmentally regulated event in Bacillus subtilis

1985 • 81 citations

Heterogeneity of RNA polymerase in Bacillus subtilis: evidence for an additional sigma factor in vegetative cells.

1981 • 80 citations

Interaction of the cAMP receptor protein with the lac promoter.

1980 • 78 citations

Mutations that affect utilization of a promoter in stationary-phase Bacillus subtilis

1985 • 76 citations

Nucleotide sequence changes produced by mutations in the lac promoter of Escherichia coli

1977 • 74 citations

Biosynthesis of RNA polymerase in Escherichia coli

1976 • 71 citations

Nucleotide sequence of a Bacillus subtilis promoter recognized by Bacillus subtilis RNA polymerase containing σ³⁷

1981 • 70 citations

Conserved nucleotide sequences in temporally controlled bacteriophage promoters

1981 • 70 citations

Regulation of expression from the glnA promoter of Escherichia coli in the absence of glutamine synthetase.

1980 • 68 citations

lac Promoter mutations located downstream from the transcription start site

1980 • 64 citations

Bacteriophage SP01 regulatory proteins directing late gene transcription in vitro

1976 • 63 citations

Identification of Different Sites of Expression for spo Loci by Transformation of Bacillus subtilis

1979 • 62 citations

Promoter recognition by sigma-37 RNA polymerase from Bacillus subtilis

1984 • 61 citations

Quantitation of RNA polymerase subunits in Escherichia coli during exponential growth and after bacteriophage T4 infection

1976 • 61 citations

T4 late transcripts are initiated near a conserved DNA sequence

1982 • 60 citations

Activation of Transcription by the Cyclic AMP Receptor Protein

1984 • 57 citations

The Cloning and Characterization of the glnF(ntrA) Gene of Klebsiella Pneumoniae: Role of glnF(ntrA) in the Regulation of the Nitrogen Fixation (nif) and other Nitrogen Assimilation Genes

1984 • 56 citations

Genes 55, alpha gt, 47 and 46 of bacteriophage T4: the genomic organization as deduced by sequence analysis.

1985 • 55 citations

Molecular Aspects of ara Regulation

1980 • 55 citations

Deletion analysis of the CAP-cAMP binding site of theEscherichia coillactose promoter

1984 • 54 citations

Chromosomal location of a structural gene for the RNA polymerase sigma factor in Escherichia coli.

1977 • 48 citations

Close contacts between σ37-RNA polymerase and a Bacillus subtilis chromosomal promoter

1982 • 47 citations

Temperature-sensitive Escherichia coli mutant producing a temperature-sensitive sigma subunit of DNA-dependent RNA polymerase.

1978 • 46 citations

Effects of reduced amount of RNA polymerase sigma factor on gene expression and growth of Escherichia coli: Studies of the rpoD40 (Amber) mutation

1981 • 44 citations

Purification of a positive regulatory subunit from phage SP01-modified RNA polymerase

1977 • 43 citations

Regulation at the glnL -Operator-Promoter of the Complex glnALG Operon of Escherichia coli

1983 • 42 citations

Endospore Formation in Bacillus

1984 • 42 citations

A new model for nitrogen control

1982 • 41 citations

Mutants of the lac promoter with large insertions and deletions between the CAP binding site and the −35 region

1984 • 41 citations

Lactose Operator Sequences and the Action of Lac Repressor

1975 • 39 citations

Utilization of one promoter by two forms of RNA polymerase from Bacillus subtilis

1985 • 39 citations

A new mutation rpoD800, affecting the sigma subunit of E. coli RNA polymerase is allelic to two other sigma mutants

1980 • 38 citations

Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell

1984 • 38 citations

Rifampin resistance mutation of Bacillus subtilis altering the electrophoretic mobility of the beta subunit of ribonucleic acid polymerase

1975 • 37 citations

Bacteriophage SPO1 genes 33 and 34

1984 • 31 citations

Properties of lac P2 in vivo and in vitro

1985 • 30 citations

The interaction of Escherichia coli core RNA polymerase with specificity-determining subunits derived from unmodified and SP82-modified Bacillus subtilis RNA polymerase.

1980 • 29 citations

Evidence that nitrogen regulatory gene ntrC of Salmonella typhimurium is transcribed from the glnA promoter as well as from a separate ntr promoter

1984 • 29 citations

Mechanism and Regulation of Tn10 Transposition

1984 • 29 citations

Regulation of hutUH operon expression by the catabolite gene activator protein-cyclic AMP complex in Klebsiella aerogenes

1984 • 29 citations

Escherichia coli RNA polymerase: purification, subunit structure, and factor requirements.

1970 • 28 citations

Lactose promoter mutation Pr115 activates an overlapping promoter within the lactose control region

1985 • 27 citations

Altered promoter selection by a novel form of Bacillus subtilis RNA polymerase

1979 • 27 citations

Genetic mapping of catabolite-resistant mutants of Bacillus subtilis

1982 • 27 citations

Bacillus subtilis sigma 28 and Escherichia coli sigma 32 (htpR) are minor sigma factors that display an overlapping promoter specificity.

1985 • 26 citations

Isolation of sigma-28-specific promoters from Bacillus subtilis DNA

1984 • 26 citations

A Salt-promoted Inhibitor of RNA Polymerase Isolated from T4 Phage-infected E. Coli

1976 • 25 citations

RNA polymerase mutant with altered sigma factor in Escherichia coli

1978 • 22 citations

Deletion analysis of theEscherichia colilactose promoter P2

1985 • 21 citations

lac Promoter mutation Pr115 generates a new transcription initiation point

1980 • 20 citations

Bacteriophage SP82 induced modifications of Bacillus subtilis RNA polymerase result in the recognition of additional RNA synthesis initiation sites on phage DNA

1978 • 19 citations

Purification and Properties of Two RNA Polymerases from Sporulating Cells of Bacillus subtilis

1978 • 19 citations

Deletion analysis of RNA polymerase interaction sites in the Escherichia coli lactose operon regulatory region

1986 • 17 citations

Utilization of a Bacillus subtilis sigma 37 promoter by Escherichia coli RNA polymerase in vivo.

1984 • 15 citations

Regulation of Transcription of glnA, the structural gene encoding glutamine synthetase, in glnA:: Mu d1 (ApR, lac) fusion strains of Salmonella typhimurium

1983 • 13 citations

Overproduction and purification of a bacteriophage SPO1-encoded RNA polymerase sigma factor.

1984 • 11 citations

Uracil incorporation in the forespore and the mother cell during spore development in Bacillus subtilis

1978 • 9 citations

Attenuation in Bacterial Operons

1983 • 5 citations

[Contacts of Escherichia coli RNA polymerase subunits with nucleotides of lacUV5 promoter].

1982 • 3 citations

Deleted Work

1955 • 0 citations