Quantification of a matrix metalloproteinase-generated aggrecan G1 fragment using monospecific anti-peptide serum

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

1986 • 3,282 citations

A novel coumarin‐labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1992 • 692 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms.

1991 • 446 citations

Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones.

1987 • 367 citations

Enzyme Coupled Immunoassay of Insulin Using a Novel Coupling Reagent

1976 • 332 citations

Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis

1993 • 325 citations

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.

1992 • 297 citations

Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage.

1992 • 273 citations

Detection of Stromelysin and Collagenase in Synovial Fluid From Patients with Rheumatoid Arthritis and Posttraumatic Knee Injury

1992 • 261 citations

[45] Proteoglycans: Isolation and Characterization

1982 • 261 citations

The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis

1990 • 197 citations

Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins

1991 • 164 citations

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain

1993 • 161 citations

Degradation of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ

1989 • 117 citations

Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Quantitative comparison with stromelysin messenger rna levels in human rheumatoid arthritis and osteoarthritis patients and in two animal models of acute inflammatory arthritis

1993 • 96 citations

Transin/stromelysin expression in the synovium of rats with experimental erosive arthritis. In situ localization and kinetics of expression of the transformation-associated metalloproteinase in euthymic and athymic Lewis rats.

1989 • 92 citations

Monoclonal antibodies recognizing protease-generated neoepitopes from cartilage proteoglycan degradation. Application to studies of human link protein cleavage by stromelysin.

1992 • 75 citations

Recombinant human interleukin‐1 β–induced increase in levels of proteoglycans, stromelysin, and leukocytes in rabbit synovial fluid

1992 • 66 citations

Hyaluronan-binding region of aggrecan from pig laryngeal cartilage. Amino acid sequence, analysis of N-linked oligosaccharides and location of the keratan sulphate

1992 • 44 citations

A semicontinuous, high-performance liquid chromatography-based assay for stromelysin

1989 • 37 citations

Cleavage of proteoglycan aggregate by leucocyte elastase

1992 • 35 citations

Substrate specificity of human fibroblast stromelysin. Hydrolysis of substance P and its analogs

1989 • 34 citations

Novel antibodies specific for proteolyzed forms of protein kinase C: production of anti-peptide antibodies available for in situ analysis of intracellular limited proteolysis

1993 • 27 citations

Inhibition of cytoplasmic aspartate aminotransferase from porcine heart by R and S isomers of aminooxysuccinate and hydrazinosuccinate.

1991 • 23 citations