Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain

1991 • 882 citations

Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis

1997 • 561 citations

Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene

1982 • 521 citations

The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis.

1994 • 518 citations

Evidence from normal expression and targeted misexpression that Bone Morphogenetic Protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis

1996 • 480 citations

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate.

1995 • 471 citations

Expression of the c-myb proto-oncogene during cellular proliferation

1986 • 360 citations

CBP as a transcriptional coactivator of c-Myb.

1996 • 347 citations

Transcriptional Elements from the Human SP-C Gene Direct Expression in the Primordial Respiratory Epithelium of Transgenic Mice

1993 • 299 citations

Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape

1992 • 296 citations

Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.

1993 • 275 citations

TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation

1997 • 268 citations

Differentiation and self-renewal in the mouse gastrointestinal epithelium

1994 • 256 citations

G₁/S Transition in Normal Human T-Lymphocytes Requires the Nuclear Protein Encoded by c-myb

1989 • 226 citations

Arrest of spermatogenesis and defective breast development in mice lacking A-myb

1997 • 223 citations

Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium.

1992 • 179 citations

Dominant interfering alleles define a role for c-Myb in T-cell development.

1994 • 172 citations

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors.

1994 • 154 citations

Expression of a proto-oncogene (proto-myb) in hemopoietic tissues of mice.

1984 • 140 citations

Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

1994 • 139 citations

Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene.

1989 • 124 citations

Expression of the bcl-2 Protooncogene in the Cycling Adult Mouse Hair Follicle

1994 • 122 citations

Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.

1992 • 115 citations

Mouse A-myb encodes a trans-activator and is expressed in mitotically active cells of the developing central nervous system, adult testis and B lymphocytes.

1994 • 108 citations

Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expression.

1992 • 108 citations

DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

1990 • 105 citations

Myb and Ets Proteins Cooperate to Transactivate an Early Myeloid Gene

1995 • 101 citations

Changes in Expression of Apoptosis-Associated Genes in Skin Mark Early Catagen

1995 • 100 citations

Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-myc.

1991 • 99 citations

Core Binding Factor Cannot Synergistically Activate the Myeloperoxidase Proximal Enhancer in Immature Myeloid Cells without c-Myb

1997 • 98 citations

MYB: An old oncoprotein with new roles

1995 • 97 citations

Amplification and expression of protooncogenes in human small cell lung cancer cell lines

1989 • 93 citations

The Homeobox Gene GBX2, a Target of the myb Oncogene, Mediates Autocrine Growth and Monocyte Differentiation

1997 • 92 citations

Characterization of a high copy number amplification at 6q24 in pancreatic cancer identifies c-myb as a candidate oncogene.

1997 • 88 citations

c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB

1997 • 86 citations

Biologic and therapeutic significance of MYB expression in human melanoma.

1994 • 85 citations

Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts.

1991 • 84 citations

Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa.

1987 • 80 citations

Comparison of the patterns of expression of rat intestinal fatty acid binding protein/human growth hormone fusion genes in cultured intestinal epithelial cell lines and in the gut epithelium of transgenic mice

1993 • 80 citations

Activation of Heat Shock Transcription Factor 3 by c-Myb in the Absence of Cellular Stress

1997 • 74 citations

The myb oncogene family of transcription factors: potent regulators of hematopoietic cell proliferation and differentiation.

1994 • 73 citations

Dissecting a Locus Control Region: Facilitation of Enhancer Function by Extended Enhancer-Flanking Sequences

1995 • 68 citations

Granulocytic Differentiation of Normal Hematopoietic Precursor Cells Induced by Transcription Factor PU.1 Correlates With Negative Regulation of the c-myb Promoter

1997 • 64 citations

Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines

1997 • 63 citations

The relationship between cell proliferation and the transcription of the nuclear oncogenes c-myc, c-myb and c-ets-1 during feather morphogenesis in the chick embryo

1991 • 62 citations

The Role of Myb Proteins in Normal and Neoplastic Cell Proliferation

1994 • 53 citations

Expression patterns of c-myb and of v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo

1992 • 49 citations

Regulation of the T-cell receptor δ enhancer by functional cooperation between c-Myb and core-binding factors

1994 • 48 citations

c-Myb Repression of c- erbB-2 Transcription by Direct Binding to the c- erbB-2 Promoter

1995 • 45 citations

Functional domains of the human B-myb gene product

1993 • 44 citations

New sites of proviral integration associated with murine promonocytic leukemias and evidence for alternate modes of c-myb activation

1992 • 43 citations

The role of c-Myb or a related factor in regulating the T cell receptor gamma gene enhancer.

1995 • 43 citations

Acute myeloid leukemia induction by amphotropic murine retrovirus (4070A): clonal integrations involve c-myb in some but not all leukemias

1991 • 41 citations

A Central Role for a Single c-Myb Binding Site in a Thymic Locus Control Region

1995 • 40 citations

Functional Analysis of the Human Adenosine Deaminase Gene Thymic Regulatory Region and Its Ability To Generate Position-Independent Transgene Expression

1992 • 38 citations

Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter

1997 • 38 citations

Activation of c-myb is an early bone-marrow event in a murine model for acute promonocytic leukemia.

1993 • 38 citations

Expression of a Proto-Oncogene (Proto-myb) in Hemopoietic Tissues of Mice

1984 • 32 citations

Only the DNA binding and transactivation domains of c-Myb are required to block terminal differentiation of murine erythroleukemia cells.

1993 • 27 citations

Murine A-myb Gene Encodes a Transcription Factor, Which Cooperates with Ets-2 and Exhibits Distinctive Biochemical and Biological Activities from c-myb

1997 • 19 citations

Interleukin-6- and Leukemia Inhibitory Factor-Induced Terminal Differentiation of Myeloid Leukemia Cells Is Blocked at an Intermediate Stage by Constitutive c-myc

1991 • 17 citations

Only the DNA Binding and Transactivation Domains of c-Myb Are Required to Block Terminal Differentiation of Murine Erythroleukemia Cells

1993 • 10 citations

Colonic cell proliferation and growth fraction in young, adult and old rats

1992 • 9 citations

Colonic epithelial cell proliferation after 40 percent small intestinal resection

1976 • 1 citations