The renal kallikrein-kinin system.

Prostaglandin biosynthesis by rabbit renomedullary interstitial cells in tissue culture. Stimulation by angiotensin II, bradykinin, and arginine vasopressin.

1977 • 351 citations

Inhibition of sodium transport by prostaglandin E2 across the isolated, perfused rabbit collecting tubule.

1977 • 344 citations

Evidence for an in vivo antagonism between vasopressin and prostaglandin in the mammalian kidney.

1975 • 279 citations

Urinary Kallikrein Excretion in Hypertensive Man

1974 • 267 citations

Arachidonic acid increases and indomethacin decreases plasma renin activity in the rabbit

1974 • 234 citations

Effects of some vasodilator drugs on transcapillary fluid exchange in renal cortex

1976 • 234 citations

Effect of prostaglandin E1 on renal hemodynamics, sodium and water excretion

1967 • 231 citations

Urinary kallikrein and plasma renin activity as determinants of renal blood flow. The influence of race and dietary sodium intake.

1977 • 226 citations

Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase II) and angiotensinase.

1977 • 202 citations

Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides.

1976 • 201 citations

THE NATURE OF THE KALLIDINS RELEASED FROM HUMAN PLASMA BY KALLIKREINS AND OTHER ENZYMES

1963 • 198 citations

Stimulation of prostaglandin synthesis by bradykinin and thrombin and their mechanisms of action on MC5-5 fibroblasts.

1976 • 196 citations

Human urinary kallikrein converts inactive to active renin and is a possible physiological activator of renin

1978 • 187 citations

RELATION BETWEEN URINARY KALLIKREIN AND RENAL FUNCTION, HYPERTENSION, AND EXCRETION OF SODIUM AND WATER IN MAN

1972 • 158 citations

SYNTHESIS OF KALLIKREINS BY RAT KIDNEY SLICES

1975 • 153 citations

Enhanced renal prostaglandin production in the dog. I. Effects on renal function.

1975 • 152 citations

FAMILIAL AGGREGATION OF URINARY KALLIKREIN CONCENTRATION IN CHILDHOOD: RELATION TO BLOOD PRESSURE, RACE AND URINARY ELECTROLYTES1

1976 • 141 citations

Influence of kallidin-10 on renal function

1964 • 141 citations

The effect of bradykinin on proximal tubular sodium reabsorption in the dog: evidence for functional nephron heterogeneity

1972 • 135 citations

The relationship between kidney and urinary kininogenase

1970 • 128 citations

The Actions of Bradykinin and Eledoisin in the Canine Isolated Kidney: Relationships to Prostaglandins

1975 • 128 citations

A sensitive isotopic procedure eor the assay oe esterase activity: measurement oe human urinary kaeeikrein

1971 • 125 citations

Effect of renal vasodilatation on the distribution of cortical blood flow in the kidney of the dog

1971 • 124 citations

The Kallikrein-Kinin System in Bartter's Syndrome and Its Response to Prostaglandin Synthetase Inhibition

1978 • 118 citations

Site of kininogenase secretion in the dog nephron

1976 • 118 citations

Mechanism of natriuretic action of bradykinin

1969 • 111 citations

Bartter's Syndrome: Urinary Prostaglandin E-like Material and Kallikrein; Indomethacin Effects

1977 • 107 citations

Carboxypeptidase in blood and other fluids—I.

1964 • 106 citations

EFFECT OF BRADYKININ ON RENAL FUNCTION.

1965 • 100 citations

Evidence for an involvement of kinins in regulation of sodium excretion

1972 • 97 citations

Isolation of membrane-bound renal kallikrein and kininase

1975 • 89 citations

Urinary Kallikrein Activity in the Hypertension of Renal Parenchymal Disease

1978 • 86 citations

Isolation of membrane-bound renal enzymes that metabolize kinins and angiotensins

1976 • 84 citations

The kinins

1976 • 84 citations

POSSIBLE INFLUENCE OF INTRARENAL GENERATION OF KININS ON PROSTAGLANDIN RELEASE FROM THE RABBIT PERFUSED KIDNEY

1976 • 75 citations

Kallikreinlike activity in perfusates and urine of isolated rat kidneys

1976 • 75 citations

Micropuncture evidence of rapid hydrolysis of bradykinin by rat proximal tubule

1976 • 74 citations

Hydrolysis of bradykinin and its higher homologues by angiotensin-converting enzyme

1974 • 70 citations

Origin and content of methionyl-lysyl-bradykinin, lysyl-bradykinin and bradykinin in human urine

1976 • 66 citations

The relationship between kallikrein and water excretion and the conditional relationship between kallikrein and sodium excretion.

1975 • 63 citations

Angiotensin I-converting enzyme in the nephron

1976 • 63 citations

Urinary kallikrein excretion and sodium metabolism in hypertensive patients.

1975 • 61 citations

Localization of kininogenase in the rat kidney

1970 • 61 citations

Bumetanide Induced Increase of Renal Blood Flow in Conscious Dogs and its Relation to Local Renal Hormones (PGE, Kallikrein and Renin)

1976 • 58 citations

The influence of antibodies against bradykinin on isotonic saline diuresis in the rat

1974 • 56 citations

Urinary kallikrein excretion in spontaneously hypertensive rats.

1975 • 55 citations

A Kallikrein-Specific Inhibitor in Rat Kidney Tubules

1976 • 51 citations

Urinary Kallikrein in Dogs with Constriction of One Renal Artery

1976 • 49 citations

Studies on rat renal cortical cell kallikrein I. Separation and measurement

1975 • 49 citations

Kallikrein-Kinin and Renin-Angiotensin Systems in Functional Renal Failure of Cirrhosis of the Liver

1977 • 48 citations

Immunochemical Studies of Plasma Kallikrein

1974 • 46 citations

Relationship between proximal sodium reabsorption and excretion of calcium, magnesium and phosphate

1973 • 45 citations

Urinary Kallikrein Excretion in Bartter's Syndrome

1976 • 44 citations

Bartter's Syndrome Results from an Imbalance of Vasoactive Hormones

1977 • 43 citations

Comparative pharmacological actions of bradykinin and related kinins of larger molecular weights

1971 • 41 citations

The Relationship of Urinary Kallikrein Activity to Renal Salt and Water Excretion

1978 • 39 citations

Renal Kallikrein Content of Spontaneously Hypertensive Rats

1975 • 37 citations

Metabolism of kinins and angiotensins in the isolated glomerulus and brush border of rat kidney.

1977 • 34 citations

Kinin-forming enzyme (kininogenin) in homogenates of rat kidney

1966 • 33 citations

Effect of spironolactone on urinary kallikrein excretion in patients with essential hypertension and in primary aldosteronism.

1977 • 29 citations

Rabbit tissue peptidases that hydrolyse the peptide hormone bradykinin. Differences in enzymic properties and concentration in rabbit tissues

1977 • 27 citations

Urinary kallikrein in experimental renal disease.

1976 • 25 citations

Distribution of Kidney Kininogenases

1976 • 24 citations

Effect of furosemide upon urinary kallikrein excretion

1973 • 22 citations

Kinin-generating and esterolytic activity of purified human urinary kallikrein (urokallikrein)

1977 • 19 citations

Inhibition of proximal tubular hydrolysis and reabsorption of bradykinin by peptides

1976 • 17 citations

Immunologic reactivity of purified human urinary kallikrein (urokallikrein) with antiserum directed against human pancreas.

1977 • 16 citations

The role of the kidney in the inactivation of injected [125I]kallikrein.

1975 • 15 citations

Effects on Rat Urinary Kallikrein Excretion of Bumetanide, Bendroflumethiazide and Hydralazine

1977 • 14 citations

Bradykininogen Synthesis by Liver

1972 • 11 citations

Vasodilators, Intrarenal Distribution of Blood Flow, and Renal Function in Isolated Perfused Canine Kidneys

1976 • 10 citations

Subcellular localization of renin and kallikrein in rat kidney.

1975 • 9 citations

Investigations on the Antihypertensive Activity of Timolol and Bendroflumethiazide and the Combination in Dogs and Rats

1976 • 6 citations

Urinary and kidney kallikrein in hypertensive rats.

1976 • 4 citations

Kininogenase in kidney after ligation of the ureter and after experimental aortic stenosis

1974 • 2 citations