Collection, manipulation and freezing of haemopoietic stem cells

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Revival of Spermatozoa after Vitrification and Dehydration at Low Temperatures

1949 • 2,007 citations

Human bone marrow colony growth in agar‐gel

1970 • 1,317 citations

Prevention of Freezing Damage to Living Cells by Dimethyl Sulphoxide

1959 • 909 citations

Erythroid colony formation in cultures of mouse and human bone marrow: Analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose‐concanavalin A

1974 • 855 citations

Het mechanism of the protective action of glycerol against haemolysis by freezing and thawing

1953 • 647 citations

Technique for Human Marrow Grafting

1970 • 483 citations

Evidence for Stem Cells in the Peripheral Blood of Mice

1962 • 475 citations

Increase in circulating stem cells following chemotherapy in man

1976 • 417 citations

Identification of megakaryocytes, macrophages, and eosinophils in colonies of human bone marrow containing neurtophilic granulocytes and erythroblasts

1979 • 392 citations

Mechanics of Freezing in Living Cells and Tissues

1956 • 391 citations

Biological Effects of Freezing and Supercooling

1962 • 307 citations

Successful engraftment of cryopreserved autologous bone marrow in patients with malignant lymphoma

1978 • 270 citations

Cryoprotective agents

1971 • 268 citations

Effects of preezing on marrow stem cell suspensions: Interactions of cooling and warming rates in the presence of pvp, sucrose, or glycerol

1970 • 251 citations

Effect of freezing on the pH and composition of sodium and potassium phosphate solutions: the reciprocal system KH2PO4Na2HPO4H2O

1959 • 237 citations

High levels of circulating haemopoietic stem cells in very early remission from acute non‐lymphoblastic leukaemia and their collection and cryopreservation

1984 • 206 citations

MAINTENANCE OF CONCENTRATION GRADIENTS AND REGULATION OF CELL VOLUME

1959 • 197 citations

The myeloid progenitor cell--its value in predicting hematopoietic recovery after autologous bone marrow transplantation

1980 • 167 citations

The Recovery of Lethally Irradiated Dogs Given Infusions of Autologous Leukocytes Preserved at -80 C

1964 • 166 citations

Circulating erythropoietic precursors assessed in culture: characterization in normal men and patients with hemoglobinopathies

1977 • 153 citations

Hemopoietic Stem Cells in Human Peripheral Blood

1975 • 149 citations

TRANSPLANTATION OF UNPURGED AUTOLOGOUS BONE-MARROW IN ACUTE MYELOID LEUKAEMIA IN FIRST REMISSION

1984 • 139 citations

Marrow autotransplantation accelerates haematological recovery in patients with malignant melanoma treated with high-dose melphalan

1979 • 128 citations

A technique for rapid isolation of bone marrow mononuclear cells using Ficoll‐Metrizoate and the IBM 2991 blood cell processor

1982 • 126 citations

Erythropoietic progenitors capable of colony formation in culture: State of differentiation

1973 • 124 citations

Megakaryocyte colony formation from human bone marrow precursors

1979 • 118 citations

The effect of addition of sodium and potassium chloride to the reciprocal system: KH2PO4-Na2HPO4-H2O on pH and composition during freezing

1959 • 117 citations

Demonstration of hemopoietic stem cells in the peripheral blood of baboons by cross circulation

1977 • 116 citations

Phase transitions and control of cellular metabolism at low temperatures

1972 • 114 citations

Treatment of Terminal Leukemic Relapse by Total-Body Irradiation and Intravenous Infusion of Stored Autologous Bone Marrow Obtained during Remission

1959 • 114 citations

Theoretical and experimental effects of cooling and warming velocity on the survival of frozen and thawed cells

1966 • 113 citations

CURE OF APLASTIC ANÆMIA IN PAROXYSMAL NOCTURNAL HÆMOGLOBINURIA BY MARROW TRANSFUSION FROM IDENTICAL TWIN: FAILURE OF PERIPHERAL-LEUCOCYTE TRANSFUSION TO CORRECT MARROW APLASIA

1979 • 110 citations

Preservation of Mouse Bone Marrow at −79° C. with Dimethyl Sulphoxide

1961 • 108 citations

Result of attempted hematopoietic reconstitution using isologous, peripheral blood mononuclear cells: a case report

1980 • 105 citations

Autologous Bone Marrow Infusion as an Adjunct in Therapy of Malignant Disease

1959 • 104 citations

Collection, Cryopreservation and Subsequent Viability of Haemopoietic Stem Cells Intended for Treatment of Chronic Granulocytic Leukaemia in Blast‐Cell Transformation

1978 • 104 citations

The Radiation Recovery Factor: Preservation by the Polge-Smith-Parkes Technique

1955 • 102 citations

Recovery of CFU-GM from cryopreserved marrow and in vivo evaluation after autologous bone marrow transplantation are predictive of engraftment.

1986 • 101 citations

High dose chemotherapy and autologous bone marrow transplantation in acute leukemias, malignant lymphomas and solid tumors

1981 • 101 citations

Megakaryocyte colony formation from human bone marrow precursors

1979 • 94 citations

Organ preservation for transplantation

1982 • 92 citations

Chemotherapy and autografting for chronic granulocytic leukaemia in transformation: probable prolongation of survival for some patients

1984 • 87 citations

Recovery of Lethally Irradiated Dogs Following Infusion of Autologous Marrow Stored at Low Temperature in Dimethyl-Sulphoxide

1962 • 83 citations

Treatment of blastic transformation of chronic granulocytic leukemia by chemotherapy, total body irradiation and infusion of cryopreserved autologous marrow.

1978 • 82 citations

Transfusion of Circulating Stem Cells

1984 • 82 citations

A technique for the separation and cryopreservation of myeloid stem cells from human bone marrow

1979 • 81 citations

Minimal Residual Disease in Acute Leukemia

1984 • 81 citations

Mobilization of hematopoietic stem cells (CFU-C) into the peripheral blood of man by endotoxin.

1977 • 80 citations

Semicontinuous flow centrifugation for the pheresis of immunocompetent cells and stem cells

1977 • 79 citations

Haemolysis by Thermal Shock

1955 • 73 citations

Mobilization of CFU-C by exercise and ACTH induced stress in man.

1978 • 71 citations

Long-term preservation of cells and tissues: a review.

1976 • 69 citations

Autologous marrow transplantation in cancer therapy.

1981 • 69 citations

The Effect of Erythrocytes on Mouse Bone Marrow Colony Development In Vitro

1971 • 68 citations

STUDY OF CELL DOSE AND STORAGE TIME ON ENGRAFTMENT OF CRYOPRESERVED AUTOLOGOUS BONE MARROW IN A CANINE MODEL

1978 • 67 citations

NITROGEN-MUSTARD THERAPY COMBINED WITH AUTOLOGOUS MARROW INFUSION

1961 • 63 citations

Collection of pluripotential hematopoietic stem cells by cytapheresis

1982 • 60 citations

The chemical and biological properties of busulphan ("Myleran").

1974 • 60 citations

AUTOLOGOUS BONE MARROW TRANSPLANTATION IN PATIENTS WITH ADULT ACUTE LEUKEMIA IN RELAPSE

1978 • 60 citations

Long-term preservation of bone marrow and stem cell pool in dogs

1978 • 59 citations

Albumin density gradient purification of canine hemopoietic blood stem cells (HBSC): long-term allogeneic engraftment without GVH-reaction.

1979 • 58 citations

Buffy coat autografts for patients with chronic granulocytic leukaemia in transformation

1981 • 56 citations

Erythrocyte Repopulation in X-Irradiated Recipients of Nucleated, Peripheral Blood Cells of Normal Mice

1960 • 56 citations

Regeneration of blood-forming organs after autologous leukocyte transfusion in lethally irradiated dogs. II. Distribution and cellularity of the marrow in irradiated and transfused animals

1976 • 56 citations

Study of granulocyte-macrophage progenitor (CFUc) preservation after slow freezing of bone marrow in the gas phase of liquid nitrogen.

1982 • 55 citations

Biochemical aspects of cryoprotective agents in freezing and thawing

1966 • 55 citations

Preservation of Viable Platelets by Freezing. Effect of Plastic Containers

1973 • 54 citations

Haematological reconstitution following high dose and supralethal chemo-radiotherapy using stored, non-cryopreserved autologous bone marrow

1983 • 50 citations

Lethal and chromosomal effects of freezing, thawing, storage time, and x-irradiation on mammalian cells preserved at −196 ° in dimethyl sulfoxide

1979 • 49 citations

Bone marrow processing and cryopreservation.

1982 • 49 citations

The Effect of Cooling Regimens on the Transplantation Potential of Marrow

1967 • 49 citations

Preservation of living cells.

1963 • 48 citations

Autologous and Isologous Bone Marrow Storage and Infusion in the Treatment of Myelo‐Suppression*

1962 • 46 citations

Recovery of haemopoiesis in lethally irradiated monkeys by frozen allogeneic bone marrow grafts.

1972 • 45 citations

Cryopreserved autologous marrow infusion following high dose cancer chemotherapy

1977 • 44 citations

PHYSIOLOGY AND ANATOMY OF THE CELL MEMBRANE: THE PHYSICAL STATE OF WATER IN THE LIVING CELL.

1965 • 42 citations

Peripheral Leukocyte Infusion into Lethally Irradiated Guinea Pigs

1965 • 42 citations

THE ASSAY OF THE TRANSPLANTATION POTENTIAL OF FRESH AND STORED BONE MARROW BY TWO IN VIVO SYSTEMS*.

1964 • 40 citations

In vitro colony formation by human bone marrow cells after freezing.

1973 • 38 citations

The Clinical Application of Bone Marrow Grafting

1962 • 37 citations

RESTORATION OF HEMATOPOIESIS IN DOGS BY INFUSION OF CRYOPRESERVED AUTOLOGOUS PERIPHERAL WHITE CELLS FOLLOWING BUSULFAN-CYCLOPHOSPHAMIDE TREATMENT

1975 • 37 citations

Diurnal variation of circulating human myeloid progenitor cells.

1980 • 36 citations

Long-term storage of bone marrow cells at liquid nitrogen and dry ice temperatures

1970 • 36 citations

Low temperature preservation of monkey marrow in dimethyl sulfoxide

1970 • 34 citations

The double barrier in bone marrow transplantation.

1974 • 34 citations

Factors in the cryopreservation of bone marrow cells from children with acute lymphocytic leukemia

1977 • 33 citations

Enrichment and cryopreservation of bone marrow progenitor cells for autologous reinfusion

1982 • 32 citations

Survival of unprotected, mammalian plateau-phase cells following freezing in liquid nitrogen

1976 • 31 citations

Delayed kinetics of recovery of haemopoiesis following autologous bone marrow transplantation. The role of excessively rapid marrow freezing rates after the release of fusion heat

1983 • 31 citations

ASTA Z 7557 (INN mafosfamide) for the in vitro treatment of human leukemic bone marrows

1984 • 31 citations

Brief Report: Transplantation of Allogeneic Canine Bone Marrow Stored at -80 C. in Dimethyl Sulfoxide

1969 • 31 citations

High dose combination chemotherapy (TACC) with and without autologous bone marrow transplantation for the treatment of acute leukaemia and other malignant diseases

1979 • 30 citations

Role of serum on cryopreservation and subsequent viability of mouse bone marrow hemopoietic stem cells

1980 • 29 citations

Liquid storage of bone marrow.

1979 • 29 citations

Storage of human lymphocytes by freezing in serum alone

1977 • 29 citations

Total Thoracic Supervoltage Irradiation followed by the Intravenous Infusion of Stored Autogenous Marrow

1959 • 28 citations

HÆMOPOIETIC RECOVERY IN EWING'S SARCOMA AFTER INTENSIVE COMBINATION THERAPY AND AUTOLOGOUS MARROW INFUSION

1980 • 28 citations

Prolonged Storage of Marrow and Its Use in the Treatment of Radiation Injury

1962 • 26 citations

Haematological Reconstitution after Autografting for Chronic Granulocytic Leukaemia in Transformation: the Influence of Previous Splenectomy

1980 • 26 citations

Description of a closed plastic bag system for the collection and cryopreservation of leukapheresis‐derived blood mononuclear leukocytes and CFUc from human donors

1980 • 24 citations

Transplantation of Bone Marrow After Preservation at −70°C

1957 • 24 citations

The processing of human bone marrow for cryopreservation and reinfusion.

1976 • 24 citations

The Long‐term Preservation of Bone Marrow

1972 • 24 citations

The preservation of bone marrow

1964 • 24 citations

The cryopreservation of colony-forming cells from the bone marrow of children with acute-lymphocytic leukemia.

1974 • 23 citations

Non-frozen preservation of committed hematopoietic stem cells from normal human bone marrow.

1981 • 22 citations

Application of bone marrow transplantation in chronic granulocytic leukaemia

1983 • 21 citations

Mobilization of colony-forming cells (CFU-C) into the peripheral blood of man by hydrocortisone.

1981 • 20 citations

Standardization and characterization of the procedure forin vitrotreatment of human bone marrow with cyclophosphamide derivatives

1985 • 20 citations

Cell preservation in a programmed cooling machine: The effect of variations in supercooling

1979 • 20 citations

The processing of human bone marrow for cryopreservation and reinfusion.

1976 • 19 citations

Cryopreservation of the human multipotent stem cell.

1982 • 19 citations

Cryopreservation of human lymphocytes and stem cells (CFU-c) in large units for cancer therapy—A report based on the data of more than 400 frozen units

1981 • 19 citations

Intensive cytoreductive regimen and autologous bone marrow transplantation in leukemia. Present status and the future. A review

1983 • 19 citations

Relation of ice formation to ultrastructural cryoinjury and cryoprotection of rough endoplasmic reticulum

1976 • 19 citations

Granulocyte‐macrophage progenitor cell preservation at 4°C

1983 • 19 citations

ASSESSMENT OF VIABILITY OF FROZEN BONE MARROW CELLS USING A CELL‐CULTURE METHOD

1968 • 18 citations

The effect of freeze rate, duration of phase transition, and warming rate on survival of frozen canine kidneys

1976 • 18 citations

Variations in Granulocyte Colony Forming Cell Numbers in Adult Blood

1979 • 17 citations

Autologous bone marrow transplantation in hematological malignancies

1984 • 16 citations

Progress in bone marrow transplantation in man

1982 • 16 citations

Collection and cryopreservation of mononuclear blood leukocytes and of CFU-C in man.

1979 • 16 citations

Studies on the Presence and Possible Oscillations of Granulocytic Progenitor Cells (CFU‐C) in Human Blood

1979 • 15 citations

Autologous bone marrow transplantation in treatment of leukemia, lymphomas, and other cancers.

1982 • 15 citations

ESTIMATION IN VIVO OF THE VIABILITY OF FROZEN AND STORED BONE MARROW

1964 • 14 citations

FURTHER OBSERVATIONS ON THE COLLECTION, STORAGE AND TRANSFUSION OF PERIPHERAL BLOOD LEUKOCYTES*

1964 • 13 citations

PRESERVATION OF GRANULOPOIETIC PRECURSORS IN NONFROZEN, STORED HUMAN BONE MARROW

1976 • 12 citations

Monkey and Mouse Bone Marrow Preservation and the Choice of Technique for Human Application*

2015 • 11 citations

THE EFFECTIVENESS OF DIFFERENT FREEZE STORAGE TECHNIQUES FOR MOUSE‐BONE‐MARROW CELL‐SUSPENSIONS*

1964 • 11 citations

Immunocompetence following autologous bone marrow transplantation.

1979 • 11 citations

Long-term preservation of canine bone marrow: in vitro studies.

1978 • 11 citations

PRESERVATION OF HUMAN GRANULOPOIETIC PRECURSORS FOLLOWING STORAGE IN THE NONFROZEN STATE

1983 • 10 citations

FACTORS INFLUENCING THE POSTSTORAGE VIABILITY OF HUMAN BONE MARROW

1964 • 10 citations

Use of Total-Body Radiation in the Treatment of Far-Advanced Malignancies

1961 • 10 citations

Cryopreservation of human bone marrow cells by a modification of the two-step cooling technique

1983 • 10 citations

Autologous marrow transplantation for patients with chronic myeloid leukemia in accelerated or blastic phase: report of 14 cases.

1986 • 9 citations

Effect of cryopreservation on recovery of cells forming colonies in diffusion chambers in mice (CFUD).

1981 • 8 citations

Purification and cryopreservation of granulomonocytic colony forming cells (GM-CFC) from the blood of patients with chronic granulocytic leukemia (CGL) for autologous transplantation.

1982 • 8 citations

Crypreservation and reinfusion of autologous bone marrow enriched for clonogenic stem cells by discontinuous cell centrifugation.

1983 • 7 citations

GCT-conditioned medium: An unsuitable stimulus for monitoring granulocyte-macrophage colony-forming cells in cryopreserved bone marrow

1983 • 7 citations

Evidence for absence of toxicity of T101 immunotoxin on human hematopoietic progenitor cells prior to bone marrow transplantation.

1985 • 7 citations

Long-term Preservation of Bone Marrow

1965 • 6 citations

Differences in the in vitro growth pattern of fresh and cryopreserved granulo-monopoietic precursors

1984 • 6 citations

Growth enhancement and serum replacement in cloning of murine mastocytoma and granulocyte/macrophage precursor cells: two distinct activities present in hemolysates.

1979 • 6 citations

Cryopreservation of marrow and stromal progenitor cells: use of long-term liquid culture as a measure of the recovery of renewable hematopoietic and stromal cells.

1983 • 6 citations

Autologous Bone Marrow Transplantation in Acute Myeloid Leukaemia in First Remission

1984 • 5 citations

Concentration of bone marrow stem cells using the haemonetics system

1982 • 5 citations

RESCUE OF RHESUS MONKEYS FROM ACUTE LETHAL GRAFT-VERSUS-HOST DISEASE USING CYCLOPHOSPHA- MIDE AND FROZEN AUTOLOGOUS BONE MARROW

1973 • 5 citations

Effect of cooling rate on human and murine hemopoietic precursor cell recovery

1983 • 4 citations

Failure of bone marrow cryopreservation in chronic granulocytic leukemia: Relation to excessive granulo‐macrophagic progenitor Pool

1986 • 4 citations

Effect of initial cell concentration of the postthaw hemolysis of frozen erythrocytes

1976 • 3 citations

Collection and cryopreservation of peripheral blood progenitor cells in chronic granulocytic leukaemia—a comparison of treated and untreated patients

1981 • 3 citations

Hematopoietic stem cells controls for autologous bone marrow transplantation monitoring

1985 • 3 citations

[Hematopoietic stem cells in peripheral blood].

1975 • 3 citations

La conservation par congélation des cellules-souches hématopoïétiques

1981 • 2 citations

The Present Status of Low-Temperature Preservation of Bone Marrow*

2015 • 2 citations

[The preservation, at -196 centigrade, of colony forming cells on agar (CFCA)].

1974 • 2 citations