Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1982 • 883 citations

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1993 • 875 citations

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.

1992 • 665 citations

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.

1994 • 644 citations

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.

1993 • 602 citations

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1992 • 567 citations

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA

1980 • 463 citations

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1985 • 383 citations

The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein.

1996 • 346 citations

The Adenovirus E1B-55K Transforming Polypeptide Modulates Transport or Cytoplasmic Stabilization of Viral and Host Cell mRNAs

1986 • 301 citations

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

1994 • 283 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport.

1985 • 234 citations

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

1984 • 221 citations

Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55k proteins

1990 • 207 citations

Getting hydrophilic compounds into cells: lessons from homeopeptides

1996 • 194 citations

Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis

1984 • 186 citations

Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

1997 • 186 citations

The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism.

1989 • 169 citations

Localization of the E1 B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies

1985 • 145 citations

Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells.

1985 • 128 citations

Characterization of cells transformed by Ad5/Ad12 hybrid early region I plasmids

1982 • 118 citations

Adenovirus E1B Proteins Are Required for Accumulation of Late Viral mRNA and for Effects on Cellular mRNA Translation and Transport

1985 • 117 citations

Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells

1996 • 101 citations

Enhanced Expression of p53 in Human Cella Infected with Mutant Adenoviruses

1994 • 91 citations

Expression and interactions of human adenovirus oncoproteins

1991 • 88 citations

Adenovirus Serotype Determines Association and Localization of the Large E1B Tumor Antigen with Cellular Tumor Antigen p53 in Transformed Cells

1985 • 68 citations

Mammalian cell growth controls reflected through protein interactions with the adenovirus E1A gene products

1994 • 61 citations

Adenovirus: Transformation and oncogenicity

1984 • 58 citations

Morphological transformation of human adenoviruses is determined to a large extent by gene products of region E1A

1983 • 53 citations

Control of p53 Expression by Adenovirus 12 Early Region 1A and Early Region 1B 54K Proteins

1996 • 36 citations

Host range mutants of adenovirus type 12 E1 defective for lytic infection, transformation, and oncogenicity

1988 • 28 citations

Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture

1997 • 25 citations

Isolation and characterization of adenovirus type 12 E1 host-range mutants defective for growth in nontransformed human cells

1988 • 20 citations

Adenovirus-Cell Interactions Early After Infection: In vitro Characteristics and Tumourigenicity of Adenovirus Type 2-transformed Rat Liver Epithelial Cells

1982 • 19 citations

Expression of the cellular p53 protein in cells transformed by adenovirus 12 and viral DNA fragments

1988 • 19 citations

Overexpression of Wild-Type p53 and c-Myc in Human Fetal Cells Transformed with Adenovirus Early Region 1

1993 • 14 citations

The Complete Nucleotide Sequence of the DNA of Human Adenovirus Type 12

1995 • 14 citations

The use of beta-galactosidase fusion proteins encoding the early region 1 transforming proteins of adenovirus type 12 to examine the humoral response in tumour-bearing animals

1991 • 6 citations