Increased substance P receptor expression by blood vessels and lymphoid aggregates inClostridium difficile-induced pseudomembranous colitis

Antibiotic-Associated Pseudomembranous Colitis Due to Toxin-Producing Clostridia

1978 • 1,392 citations

Clostridium difficile Colitis

1994 • 1,328 citations

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

1979 • 1,199 citations

Effect of Neuropeptides on Production of Inflammatory Cytokines by Human Monocytes

1988 • 929 citations

Clostridium difficile: its disease and toxins

1988 • 574 citations

Intraneuronal Substance P Contributes to the Severity of Experimental Arthritis

1984 • 521 citations

Mast cell heterogeneity: effects of neuroenteric peptides on histamine release.

1985 • 440 citations

Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.

1988 • 281 citations

CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.

1994 • 274 citations

Pseudomembranous colitis.

1977 • 226 citations

Differential effects of Clostridium difficile toxins A and B on rabbit ileum

1987 • 204 citations

Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit.

1994 • 196 citations

Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum

1994 • 167 citations

Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon.

1986 • 155 citations

Antibiotic-associated colitis.

1984 • 139 citations

Receptors for sensory neuropeptides in human inflammatory diseases: Implications for the effector role of sensory neurons

1989 • 138 citations

Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis

1995 • 133 citations

Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.

1991 • 77 citations

Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium.

1993 • 76 citations

Activation of human neutrophils by substance P: effect on FMLP-stimulated oxidative and arachidonic acid metabolism and on antibody-dependent cell-mediated cytotoxicity.

1989 • 70 citations

Sensory Nerves, Neuropeptides, and Asthma

1991 • 26 citations

Effect of substance P on the expression of an adhesion molecule ICAM-1 in human vascular endothelial cells

1993 • 21 citations