The immunopathology of Hodgkin's disease

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

The Raji cell radioimmune assay for detecting immune complexes in human sera.

1976 • 744 citations

Prostaglandin-Producing Suppressor Cells in Hodgkin's Disease

1977 • 552 citations

Expression of a receptor for IgM by human T cells in vitro

1975 • 444 citations

Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines.

1976 • 388 citations

Classification and biological nature of established human hematopoietic cell lines

1975 • 356 citations

The separation, long-term cultivation, and maturation of the human monocyte.

1977 • 320 citations

Relation between the pathological nature and the growth rate of human tumors

1971 • 310 citations

Impaired Lymphocyte Function in Untreated Hodgkin's Disease

1974 • 294 citations

Criteria for involvement of lymph node, bone marrow, spleen, and liver in Hodgkin's disease.

1971 • 277 citations

The monoclonality of human B-cell lymphomas.

1977 • 268 citations

Delayed hypersensitivity in Hodgkin's disease

1972 • 244 citations

Disorders of Suppressor Immunoregulatory Cells in the Pathogenesis of Immunodeficiency and Autoimmunity

1978 • 235 citations

Tumorigenicity of human hematopoietic cell lines in athymic nude mice

1977 • 219 citations

Impaired Antibody Response to Pneumococcal Vaccine after Treatment for Hodgkin's Disease

1978 • 216 citations

Hodgkin's disease. An immunodepleting and immunosuppressive disorder.

1975 • 215 citations

The Origin and Development of Human Tumors Studied with Cell Markers

1974 • 208 citations

THE NATURE OF REED-STERNBERG CELLS AND OTHER MALIGNANT " RETICULUM " CELLS

1974 • 206 citations

The Nature of Immune Complexes in Human Cancer Sera

1977 • 204 citations

“sternberg‐reed” giant cells of hodgkin's disease: Cultivation in vitro, heterotransplantation, and characterization as neoplastic macrophages

1977 • 202 citations

Lymphocyte surface characteristics in malignant lymphoma

1975 • 199 citations

Epstein‐Barr virus (EBV)‐associated antibody patterns in malignant lymphoma and leukemia. I. Hodgkin's disease

1970 • 193 citations

Epidemiology of Hodgkin's disease in the young

1977 • 180 citations

Exogenous Immunoglobulin and the Macrophage Origin of Reed–Sternberg Cells in Hodgkin's Disease

1978 • 180 citations

Synthesis of the second component of complement by long-term primary cultures of human monocytes.

1976 • 171 citations

BINDING OF SOLUBLE IMMUNE COMPLEXES TO HUMAN LYMPHOBLASTOID CELLS

1974 • 162 citations

PATHOGENESIS OF HODGKIN'S DISEASE

1972 • 160 citations

The C1q Binding Test for Soluble Immune Complexes: Clinical Correlations Obtained in Patients With Cancer 2

1977 • 158 citations

Immunologic aspects and pathology of the malignant lymphomas

1978 • 157 citations

Ferritinaemia in Leukaemia and Hodgkin's Disease

1973 • 144 citations

IMMUNOHISTOCHEMICAL DEMONSTRATION OF IgG IN REED-STERNBERG AND OTHER CELLS IN HODGKIN'S DISEASE

1974 • 143 citations

Quantitation of T and B lymphocytes and cellular immune function in Hodgkin's disease

1975 • 141 citations

Impaired Cell-Mediated Immunity in Hodgkin's Disease Mediated by Suppressor Lymphocytes and Monocytes

1978 • 139 citations

Acute nephrotic syndrome as a manifestation of active Hodgkin's disease

1971 • 131 citations

Effect of Levamisole on E-Rosette-Forming Cells in Vivo and in Vitro in Hodgkin's Disease

1976 • 130 citations

Value of Genetic Variants of Glucose-6-Phosphate Dehydrogenase in Tracing the Origin of Malignant Tumors

1967 • 129 citations

Biology of the human malignant lymphomas I. Establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas

1974 • 128 citations

Lymphocyte abnormalities in untreated patients with Hodgkin's disease

1976 • 124 citations

Interaction between Serum Factors and T Lymphocytes in Hodgkin's Disease

1976 • 120 citations

Impaired delayed-hypersensitivity responses in 154 patients with untreated Hodgkin's disease.

1973 • 117 citations

RNA in Human Leukemic Cells Related to the RNA of a Mouse Leukemia Virus

1972 • 117 citations

Ferritin, a Hodgkin's Disease Associated Antigen

1974 • 112 citations

Clinical Relevance of Circulating Immune Complexes in Human Leukemia

1977 • 112 citations

Immunologic status of Hodgkin's disease

1966 • 108 citations

Summary of infectious complications occurring in patients with Hodgkin's disease.

1966 • 107 citations

Inter- and Intraspecies Contamination of Human Breast Tumor Cell Lines HBC and BrCa5 and Other Cell Cultures

1977 • 106 citations

Malignant Lymphoma

1973 • 104 citations

Impaired Humoral Immunity in Treated Hodgkin's Disease

1977 • 103 citations

The complexity of immunohistochemical staining pattern of hodgkin and sternberg‐reed cells—demonstration of immunoglobulin, albumin, α₁‐antichymotrypsin and lysozyme

1978 • 103 citations

Fulminant sepsis after the successful treatment of Hodgkin's disease

1977 • 103 citations

Nephrotic syndrome in Hodgkin's disease

1976 • 97 citations

T and B lymphocytes and Reed-Sternberg cells in Hodgkin's disease lymph nodes and spleens.

1976 • 96 citations

Chromosomes in leukemia and lymphoma.

1978 • 93 citations

Hodgkin's Disease: Evidence for a Tumor-Associated Antigen

1971 • 93 citations

Studies of Cell Subpopulations Mediating Mitogen Hyporesponsiveness in Patients with Hodgkin's Disease

1978 • 90 citations

Impaired Lymphocyte Transformation in Hodgkin's Disease. EVIDENCE FOR DEPLETION OF CIRCULATING T-LYMPHOCYTES

1973 • 89 citations

Immunological Diagnosis of Leukemias and Lymphomas

1977 • 89 citations

Proliferation characteristics of the various classes of cells in Hodgkin's disease

1969 • 89 citations

Rosetting and other reactions of the Reed‐Sternberg cell

1977 • 88 citations

IMMUNOGLOBULIN-POSITIVE REED-STERNBERG CELLS IN HODGKIN'S DISEASE

1973 • 87 citations

Suppression of Lymphoproliferation by High Concentrations of Normal Human Mononuclear Leukocytes

1977 • 87 citations

Tissue culture studies in Hodgkin's disease morphologic, cytogenic, cell surface, and enzymatic properties of cultures derived from splenic tumors

1977 • 85 citations

Ferritin on the surface of lymphocytes in Hodgkin's disease patients. A possible blocking substance removed by levamisole.

1977 • 84 citations

Monocyte-mediated inhibition of lymphocyte blastogenesis in Hodgkin disease

1978 • 79 citations

Coombs'-positive Hemolytic Anemia in Hodgkin's Disease

1967 • 76 citations

Significance of the Changes in the Circulating Lymphoid Cells in Hodgkin's Disease

1969 • 74 citations

The significance of intracytoplasmic proteins in Reed-Sternberg cells

1978 • 74 citations

Clonal growth of Hodgkin cells

1975 • 74 citations

In Vitro Splenic IgG Synthesis in Hodgkin's Disease

1973 • 74 citations

CIRCULATING IMMUNE COMPLEXES AND SYMPTOMS IN HODGKIN'S DISEASE

1976 • 71 citations

The cytochemical demonstration of intracellular immunoglobulin. In neoplasms of lymphoreticular tissue.

1976 • 71 citations

Quantitation of immunocompetence in Hodgkin's disease.

1975 • 70 citations

Nuclear DNA Sequences Present in Human Leukemic Cells and Absent in Normal Leukocytes

1972 • 68 citations

Lacunar cells of nodular sclerosing Hodgkin's disease:An ultrastructural and immunohistologic study

1977 • 67 citations

Ultrastructural study of Reed-Sternberg cells. Comparison with transformed lymphocytes and histiocytes.

1976 • 67 citations

Hodgkin's disease and other human malignant lymphomas: advances and prospects--G.H.A. Clowes Memorial Lecture.

1976 • 66 citations

INCREASE OF T LYMPHOCYTES IN THE SPLEEN IN HODGKIN'S DISEASE

1974 • 66 citations

Immunoglobulin complexes in sera of patients with malignancy

1977 • 66 citations

Isolation of circulating immune complexes using Raji cells. Separation of antigens from immune complexes and production of antiserum.

1978 • 66 citations

Circulating immune complexes in patients with malignant lymphomas and solid tumors

1977 • 64 citations

Hodgkin's disease: An immunohistochemical and histological study

1978 • 64 citations

Isolation of variants in phagocytosis of a macrophage-like continuous cell line.

1977 • 62 citations

Observations on cell lines derived from a patient with Hodgkin's disease.

1978 • 61 citations

Increased ferritin synthesis and release by hodgkin's disease peripheral blood lymphocytes¹

1977 • 61 citations

Ultrastructural studies of Hodgkin's disease.

1973 • 60 citations

Lymphocyte Reactivity in Hodgkin's Disease: A Lymphocyte Civil War

1973 • 60 citations

Ultrastructural aspects of in vitro development of monocytes into macrophages, epithelioid cells, and multinucleated giant cells.

1967 • 59 citations

Characterization of immunoglobulins in Hodgkin cells

1977 • 59 citations

Correlation between immune complexes and prognostic factors in Hodgkin's disease.

1978 • 55 citations

Enzyme Histochemistry of the Cells in Hodgkin's Disease and Allied Disorders

1961 • 54 citations

The Staging and Treatment of Hodgkin's Disease

1978 • 54 citations

Cellular Associations in Normal and Abnormal Lymphocytes (Illustrated by a Film)

1959 • 53 citations

Sternberg-Reed Cells in the Peripheral Blood of Patients with Hodgkin’s Disease

1966 • 51 citations

SURFACE CHARACTERISTICS OF HODGKIN'S LYMPHOMA CELLS

1974 • 50 citations

Circulating immune complexes in Hodgkin's disease

1978 • 49 citations

Restoration of cellular immune response by levamisole in patients with Hodgkin's disease.

1975 • 49 citations

Malignant potential of a cell line isolated from the peripheral blood in infectious mononucleosis

1971 • 48 citations

A case control study on immunity to two epstein-barr virus-associated antigens, and to herpes simplex virus and adenovirus in a population-based group of patients with hodgkin's disease in denmark, 1971–73

1977 • 47 citations

Virus-like Agents from Patients with Hodgkin's Disease

1971 • 46 citations

The ultrastructure of the abnormal reticulum cells in Hodgkin's disease

1975 • 45 citations

Pathogenesis of hodgkin's disease: Separation and culture of different kinds of cells from hodgkin's disease in a sterile isokinetic gradient of ficoll in tissue culture medium

1973 • 45 citations

Isolation of a type C RNA virus from an established human histiocytic lymphoma cell line.

1977 • 45 citations

Detection of ferritin as a circulating tumor-associated antigen in Hodgkin's disease.

1973 • 42 citations

Long term cultures of Hodgkin's tissue. A morphologic and radioautographic study.

1973 • 39 citations

Studies of Antigens Associated With Hodgkin’s Disease

1972 • 39 citations

Decreased monocyte function in patients with Hodgkin's disease

1978 • 38 citations

Subclinical immune complex nephritis in patients with Hodgkin's disease.

1974 • 38 citations

Persisting lymphocyte deficiences during remission in Hodgkin's disease.

1977 • 38 citations

Immunologic Profile of Patients with Cured Hodgkin's Disease

1977 • 38 citations

Binding of Soluble Immune Complexes in Serum of Patients with Hodgkin's Disease to Tissue Cultures Derived from the Tumor

1977 • 38 citations

Concanavalin A receptors on the surface membrane of lymphocytes from patient's with Hodgkin's disease and other malignant lymphomas.

1975 • 38 citations

Changes in the surface membrane of lymphocytes from patients with chronic lymphocytic leukemia and hodgkin's disease

1975 • 36 citations

Immune deposits in Hodgkin's disease with nephrotic syndrome.

1972 • 36 citations

Idiopathic thrombocytopenic purpura in Hodgkin's disease.A rare occurrence of no prognostic significance

1978 • 36 citations

Development of immunocytes and immunoglobulin production in long‐term cultures from normal and malignant human lymph nodes

1968 • 35 citations

Membrane difference in peripheral blood lymphocytes from patients with chronic lymphocytic leukemia and Hodgkin's disease.

1975 • 34 citations

Lymphocyte subpopulations of lymph nodes and spleens in Hodgkin's disease

1978 • 34 citations

B and T lymphocytes in Hodgkin's disease. Analysis at diagnosis and following therapy.

1976 • 33 citations

Clustering and aggregation of exposures in Hodgkin's disease

1977 • 33 citations

Evidence for RNA tumor viruses in human lymphomas including Burkitt's disease.

1973 • 33 citations

Cell proliferation in Hodgkin's disease.

1973 • 33 citations

Malignant Lymphoma

1973 • 33 citations

Purification of Hodgkin's Disease Tumor-Associated Antigens

1973 • 33 citations

Rauscher-leukemia-virus-related sequences in human DNA: presence in some tissues of some patients with hemotopoietic neoplasias and absence in DNA from other tissues.

1977 • 32 citations

SURFACE CHARACTERISTICS OF HODGKIN'S CELLS

1975 • 31 citations

Immunological Defects in Healthy Twin Siblings to Patients with Hodgkin's Disease

1977 • 30 citations

Cultural, morphological, cell membrane, enzymatic, and neoplastic properties of cell lines derived from a Hodgkin's disease lymph node.

1978 • 29 citations

The Cytogenetics and Cell Metabolism of Circulating Reed‐Sternberg Cells

1966 • 29 citations

Deficiency of lymphocyte antigen recognition in Hodgkin's disease.

1973 • 29 citations

MIXED-LYMPHOCYTE REACTION AS ASSAY FOR IMMUNOLOGICAL COMPETENCE OF LYMPHOCYTES FROM PATIENTS WITH HODGKIN'S DISEASE

1972 • 29 citations

Established Cell Lines as Tools in the Study of Human Lymphoma and Myeloma Cell Characteristics

1977 • 28 citations

Abnormalities of complement and its components in patients with acute leukemia, Hodgkin's disease, and sarcoma.

1976 • 28 citations

Chromosome changes in Hodgkin's disease.

1973 • 28 citations

In vitro evidence of normal lymphocyte function in some patients with Hodgkin's disease and negative delayed cutaneous hypersensitivity.

1973 • 28 citations

Spontaneous pyrogen production by mouse histiocytic and myelomonocytic tumor cell lines in vitro.

1978 • 27 citations

Functional characterization of cells separated from suspensions of Hodgkin diseases tumor cells in an isokinetic gradient.

1977 • 27 citations

Follow-up studies on the immune status of patients with Hodgkin's disease after splenectomy and treatment, in relapse and remission

1977 • 27 citations

Quantitative ultrastructural analysis of in vivo lymphocyte-Reed-Sternberg cell interactions in Hodgkin's disease.

1973 • 27 citations

Growth of cultured cells from patients with Hodgkin's disease and transplantation into nude mice.

1977 • 27 citations

Cytochemical, Ultrastructural and Immunological Studies of Circulating Reed–Sternberg Cells

1978 • 27 citations

The search for a viral agent in Hodgkin's disease

1974 • 27 citations

B lymphocyte antigens in the differential diagnosis of human neoplasia

1978 • 26 citations

The ability of tumor cells of the lymphoreticular system to grow in vitro.

1972 • 26 citations

Lymphocyte Subpopulations in Hodgkin’s Disease

1976 • 25 citations

Hodgkin's disease complicated by the nephrotic syndrome

1976 • 25 citations

Immune complex mediated diseases

1978 • 25 citations

Production of leukocyte inhibitory factor (LIF) in Hodgkin's disease

1977 • 24 citations

In Vitro Lymphocyte Dysfunction in Hodgkin's Disease

1976 • 23 citations

CYTOLOGY OF THE STERNBERG‐REED CELL AS REVEALED BY THE ELECTRON MICROSCOPE

1958 • 23 citations

Histogenesis of Splenic Lesions in Hodgkin’s Disease

1976 • 22 citations

Complement receptor B lymphocytes in nodular sclerosing Hodgkin's disease

1977 • 22 citations

Increased T lymphocytes and IgMEA-receptor lymphocytes in Hodgkin's disease spleens

1977 • 22 citations

Cytoplasmic inclusions and the characteristics of Hodgkin's diseased lymph nodes in tissue culture.

1949 • 22 citations

Viruses in Human Tumors. I. Hodgkin's Disease

1969 • 22 citations

Hodgkin's cells and attached lymphocytes. A possible prognostic indicator in splenic tumor

1979 • 21 citations

Correlation of serum IgD level with clinical and histologic parameters in Hodgkin disease

1978 • 19 citations

E-rosette inhibiting substance in Hodgkin's disease spleen extracts.

1977 • 19 citations

Immunoglobulin in Reed‐Sternberg and Hodgkin cells

1978 • 19 citations

A cluster of Hodgkin's disease in a small community: evidence for environmental factors.

1978 • 18 citations

T Lymphocytes and Reed–Sternberg Cells in Spleen of Hodgkin's Disease

1974 • 18 citations

The influence of splenectomy on the in vitro lymphocyte response to phytohemagglutinin and pokeweed mitogen in Hodgkin's disease

1975 • 17 citations

Lymphocyte receptors for concanavalin A in Hodgkin disease

1978 • 16 citations

Immunoglobulin synthesis in long term cultures of lymph nodes from Hodgkin's disease

1967 • 16 citations

Neoplastic macrophages grown from human leukaemic monocytes

1977 • 16 citations

Evidence for infectious component of Hodgkin's disease and related considerations.

1976 • 16 citations

Antibody-Dependent Lymphocytotoxicity Induced by Immunoglobulin G from Hodgkin's Disease Splenic Lymphocytes

1978 • 15 citations

Current epidemiological evidence for transmission of Hodgkin's disease.

1976 • 15 citations

A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production.

1978 • 15 citations

Some Characteristics of a Human Cell Line (AICHI-4) Established From Tumorous Lymphatic Tissue of Hodgkin's Disease<xref ref-type="fn" rid="FN2">2</xref>

1968 • 15 citations

An Antigen in Hodgkin's Disease Tissue Cultures: Fluorescent Antibody Studies

1974 • 14 citations

Cytological basis of histological typing of diffuse Hodgkin's disease. Demonstration of an implied misnomer in the terminology of the Rye classification.

1978 • 14 citations

Hodgkin’s Disease: A War Between T-Lymphocytes and Transformed Macrophages?

1976 • 14 citations

Cancer Chemotherapy II. The Twenty-Second Hahnemann Symposium.

1972 • 14 citations

Hodgkin's disease—A report from Buenos Aires, Argentina

1973 • 14 citations

A Tumor Antigen in Tissue Cultures Derived from Patients with Hodgkin's Disease

1973 • 12 citations

Correlation between Immune Complexes and Prognostic Factors in Hodgkin's Disease

1978 • 12 citations

Comparative studies on distribution of DMBA‐³H and 7‐hydroxy‐DMBA‐³H and their carcinogenic activity

1970 • 12 citations

Differences in membrane structure between suspended and attached mouse neuroblastoma cells

1977 • 12 citations

Quantitative Cytology and Cytochemistry of Hodgkin's Tissue Labelled in vivo with Tritiated Thymidine

1973 • 11 citations

On the Fate of DNA Synthesizing Lymphoid Blood Cells in Hodgkin's Disease

1975 • 11 citations

Primary cultures of human spleen macrophages in vitro

1976 • 11 citations

Human Malignant Lymphomas in Vitro

1978 • 10 citations

An Antigen in Hodgkin's Disease Tissue Cultures: Radioiodine-Labeled Antibody Studies

1974 • 10 citations

IgM RECEPTORS ON CELLS IN HODGKIN'S DISEASE

1976 • 9 citations

Nuclear DNA sequences present in human leukemic cells and absent in normal leukocytes

1973 • 9 citations

Aetiologic leads in the malignant lymphomas

1974 • 8 citations

Cellular immunity to Hodgkin's splenic tissue measured by leucocyte migration inhibition.

1976 • 8 citations

T and B lymphocytes and monocytes in the spleen in Hodgkin's disease: the increase in T lymphocytes in involved spleens

1977 • 7 citations

A combined clinical and histological assessment of survival of patients with Hodgkin's disease

1971 • 7 citations

Electron microscopy of hodgkin's disease tissue cultures

1979 • 7 citations

Chromatographic and Electrophoretic Analysis of an Antigen in Hodgkin's Disease Tissue Cultures23

1977 • 7 citations

Symptom relief with levamisole in stage IV Hodgkin's disease.

1977 • 6 citations

Absence of IgG lymphocytotoxins in untreated Hodgkin's disease (HD) patients.

1978 • 6 citations

Sensitisation to Hodgkin's disease spleen tissue in patients with malignant lymphoma: follow-up study.

1976 • 5 citations

Case 24-1978

1978 • 5 citations

Complexing Rauscher leukemia virus reverse transcriptase with human plasma ribonuclease from Hodgkin's disease patients.

1977 • 5 citations

The oncogenicity of cell cultures isolated from normal subjects and from patients with infectious mononucleosis, Letterer-Siwe disease or Hodgkin disease.

1973 • 4 citations

Hodgkin's disease. Historical notes.

1977 • 4 citations

[Morphological, ultrastructural and cytochemical study of in vitro cultured cells from 2 Hodgkin's lymphomas].

1973 • 3 citations

Reaction of Immune Complexes With Hodgkin's Disease Tissue Cultures: Radioimmune Assay and Immunoferritin Electron Microscopy<xref ref-type="fn" rid="FN2">2</xref>

1979 • 3 citations

Lymphocyte function in Hodgkin's Disease.

1976 • 2 citations

A Surface Antigen Associated With Hodgkin's Disease: Brief Communication 2

1977 • 2 citations

All in the Mind

1969 • 1 citations

Occurrence in Human Bone Marrows of an Antigen Released from Continuous Cell Cultures Derived from Human Leukemia

1976 • 1 citations