Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier.

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

FRACTURE FACES OF ZONULAE OCCLUDENTES FROM "TIGHT" AND "LEAKY" EPITHELIA

1973 • 1,086 citations

Studies of Intestinal Digestion and Absorption in the Human1

1957 • 1,034 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Biological Membranes: The Physical Basis of Ion and Nonelectrolyte Selectivity

1969 • 686 citations

Barrier function of epithelia

1981 • 616 citations

Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula Occludens

1978 • 569 citations

Structure, biochemistry, and assembly of epithelial tight junctions

1987 • 532 citations

Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat

1987 • 525 citations

Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush Border

1985 • 525 citations

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

1987 • 514 citations

Cingulin, a new peripheral component of tight junctions

1988 • 505 citations

Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.

1986 • 433 citations

Ionic Conductances of Extracellular Shunt Pathway in Rabbit Ileum

1972 • 416 citations

Occluding junction structure-function relationships in a cultured epithelial monolayer.

1985 • 412 citations

A human colonic tumor cell line that maintains vectorial electrolyte transport

1984 • 398 citations

Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.

1988 • 398 citations

Intestinal absorptive cell tight junctions are linked to cytoskeleton

1987 • 343 citations

Loosening tight junctions. Lessons from the intestine.

1989 • 329 citations

Occluding junctions and cytoskeletal components in a cultured transporting epithelium

1980 • 327 citations

Regulation of epithelial tight junction permeability by cyclic AMP

1981 • 296 citations

Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers.

1987 • 289 citations

Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study.

1988 • 246 citations

Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction

1987 • 243 citations

Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters

1987 • 216 citations

Differential effects of Clostridium difficile toxins A and B on rabbit ileum

1987 • 204 citations

The histopathologic spectrum of acute self-limited colitis (acute infectious -type colitis)

1982 • 201 citations

Partitioning of paracellular conductance along the ileal crypt-villus axis: A hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships

1984 • 187 citations

Tumor promoter-induced changes in the permeability of epithelial cell tight junctions

1981 • 185 citations

Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins

1980 • 182 citations

Contraction of isolated brush borders from the intestinal epithelium.

1976 • 178 citations

Increases in guinea pig small intestinal transepithelial resistance induced by osmotic loads are accompanied by rapid alterations in absorptive-cell tight-junction structure.

1983 • 163 citations

Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes

1986 • 163 citations

Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro.

1982 • 157 citations

Functional coupling of tight junctions and microfilaments in T84 monolayers

1988 • 154 citations

Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia

1990 • 140 citations

Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization.

1984 • 139 citations

Streaming potentials in the rat small intestine

1966 • 128 citations

Ca2+ regulation of tight-junction permeability and structure in Necturus gallbladder

1983 • 118 citations

Reactivation of intestinal epithelial cell brush border motility: ATP-dependent contraction via a terminal web contractile ring.

1982 • 109 citations

A freeze-etch study of the tight junctions of the rat kidney tubules.

1974 • 103 citations

The selective and superoxide-independent disruption of intestinal epithelial tight junctions during leukocyte transmigration.

1988 • 91 citations

Structure and permeability of goblet cell tight junctions in rat small intestine

1982 • 78 citations

Countercurrent mechanisms in the mammalian gastrointestinal tract

1986 • 76 citations

Mechanical tension induces lateral movement of intramembrane components of the tight junction: studies on mouse mammary cells in culture.

1983 • 75 citations

Transepithelial migration of human neutrophils: an in vitro model system.

1980 • 64 citations

Macromolecules can pass through occluding junctions of rat ileal epithelium during cholinergic stimulation

1987 • 61 citations

Heterogeneity of tight junction morphology in extrapulmonary and intrapulmonary airways of the rat

1980 • 54 citations

cAMP-mediated effects of ouabain and theophylline on paracellular ion selectivity

1984 • 45 citations

Selective absorption of carbohydrates

1930 • 37 citations

ABSORPTION OF GLUCOSE AND METHIONINE FROM THE HUMAN INTESTINE; THE INFLUENCE OF THE GLUCOSE CONCENTRATION IN THE BLOOD AND IN THE INTESTINAL LUMEN

1952 • 32 citations

Transepithelial chemotaxis of rat peritoneal exudate cells.

1983 • 29 citations