Association between Early-Onset Parkinson's Disease and Mutations in theParkinGene

Parkinsonism

1967 • 11,463 citations

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

1997 • 7,814 citations

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1998 • 5,063 citations

AGEING AND PARKINSON'S DISEASE: SUBSTANTIA NIGRA REGIONAL SELECTIVITY

1991 • 3,275 citations

Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale

1987 • 2,219 citations

Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.

1997 • 835 citations

A Wide Variety of Mutations in the Parkin Gene Are Responsible for Autosomal Recessive Parkinsonism in Europe

1999 • 526 citations

A susceptibility locus for Parkinson's disease maps to chromosome 2p13

1998 • 461 citations

Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q

1998 • 366 citations

The role of inheritance in sporadic Parkinson's disease: Evidence from a longitudinal study of dopaminergic function in twins

1999 • 302 citations

Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals

1998 • 293 citations

Familial juvenile Parkinsonism.

1979 • 261 citations

A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor

1999 • 255 citations

Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism

1996 • 235 citations

Protein misfolding and degradation in genetic diseases

1999 • 223 citations

Point Mutations (Thr240Arg and Ala311Stop) in theParkinGene

1998 • 177 citations

Deletions in the Parkin gene and genetic heterogeneity in a Greek family with early onset Parkinson's disease

1998 • 153 citations

Cloning of Rat Parkin cDNA and Distribution of Parkin in Rat Brain

2000 • 45 citations