Carbonic Anhydrase (CA IX) Expression, a Potential New Intrinsic Marker of Hypoxia: Correlations with Tumor Oxygen Measurements and Prognosis in Locally Advanced Carcinoma of the Cervix 1

Hypoxia-inducible expression of tumor-associated carbonic anhydrases.

2000 • 1,246 citations

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

2000 • 1,087 citations

HUMAN CARBONIC ANHYDRASES AND CARBONIC ANHYDRASE DEFICIENCIES

1995 • 809 citations

Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment.

1994 • 507 citations

Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix.

2001 • 320 citations

p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription

1998 • 284 citations

A novel quasi-viral agent, MaTu, is a two-component system

1992 • 283 citations

Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro

2000 • 276 citations

Immunohistochemical Study of Colorectal Tumors for Expression of a Novel Transmembrane Carbonic Anhydrase, MN/CA IX, with Potential Value as a Marker of Cell Proliferation

1998 • 268 citations

Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney.

1997 • 252 citations

Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.

1998 • 244 citations

Expression of MaTu‐MN protein in human tumor cultures and in clinical specimens

1993 • 209 citations

Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas.

1994 • 187 citations

Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix

1993 • 186 citations

MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas

1999 • 161 citations

Targeting of renal cell carcinoma with iodine-131-labeled chimeric monoclonal antibody G250.

1997 • 157 citations

Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions.

1997 • 147 citations

A carbonic anhydrase inhibitor as a potential modulator of cancer therapies.

1993 • 122 citations

Carbonic anhydrase IX antigen differentiates between preneoplastic malignant lesions in non-small cell lung carcinoma

1999 • 107 citations

Measurement of tumor oxygenation

1998 • 91 citations

Changes in oxygenation during radiotherapy in carcinoma of the cervix

1999 • 59 citations

The Radiotherapy of Malignant Disease

1991 • 54 citations

Expression of the MN antigen in cervical papanicolaou smears is an early diagnostic biomarker of cervical dysplasia.

1996 • 47 citations

Study of in vitro conditions modulating expression of MN/CA IX protein in human cell lines derived from cervical carcinoma.

1999 • 18 citations