Physical and Chemical Changes Induced in Nucleic Acids by Ultraviolet Light

GENETICS OF HUMAN CELL LINES

1960 • 649 citations

A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS

1963 • 564 citations

Heterogeneity in Deoxyribonucleic Acids: I. Dependence on Composition of the Configurational Stability of Deoxyribonucleic Acids

1959 • 490 citations

Isolation and identification of the irradiation product of thymine

1960 • 474 citations

Photochemistry of Proteins and Nucleic Acids

1964 • 361 citations

Thymine Dimers and Inhibition of DNA Synthesis by Ultraviolet Irradiation of Cells

1963 • 344 citations

EVIDENCE THAT ULTRAVIOLET-INDUCED THYMINE DIMERS IN DNA CAUSE BIOLOGICAL DAMAGE

1962 • 318 citations

Thymine Photoproducts but not Thymine Dimers Found in Ultraviolet-Irradiated Bacterial Spores

1965 • 253 citations

The occurrence of a new pyrimidine base replacing thymine in a bacteriophage DNA: 5-hydroxymethyl uracil

1962 • 199 citations

Dose dependent decrease in extractability of DNA from bacteria following irradiation with ultraviolet light or with visible light plus dye

1962 • 197 citations

The ultraviolet photochemistry of thymidylyl-(3′→5′)-thymidine

1964 • 192 citations

Nature of the Photoreactivable Ultra-Violet Lesion in Deoxyribonucleic Acid

1963 • 179 citations

Studies on Ultraviolet Irradiation of Escherichia coli Containing 5-Bromouracil in its DNA

1960 • 163 citations

Effect of Halogenated Pyrimidines on Radiosensitivity of E. coli

1962 • 159 citations

Photochemical Reactions in Frozen Solutions

1961 • 155 citations

On the nature of thymine photoproduct

1961 • 146 citations

PHOTOCHEMICAL REACTIONS OF THYMINE, URACIL, URIDINE, CYTOSINE AND BROMOURACIL IN FROZEN SOLUTION AND IN DRIED FILMS*

1963 • 144 citations

Pyrimidine dimers in UV-irradiated poly dI:dC.

1965 • 136 citations

Photochemistry of thymine dimers

1962 • 128 citations

Genetic transformation II. The significance of damage to the DNA molecule

1959 • 127 citations

ULTRAVIOLET LIGHT INDUCED LINKING OF DEOXYRIBONUCLEIC ACID STRANDS AND ITS REVERSAL BY PHOTOREACTIVATING ENZYME

1961 • 126 citations

The effects of ultraviolet light on the biological and physical chemical properties of deoxyribonucleic acids

1961 • 124 citations

A Reversible Photochemical Alteration of Uracil and Uridine

1949 • 118 citations

A Mixed Photoproduct of Uracil and Cysteine (5-S-Cysteine-6-hydrouracil). A Possible Model for the in Vivo Cross-Linking of Deoxyribonucleic Acid and Protein by Ultraviolet Light^*

1966 • 116 citations

Chemistry of the Dihydropyrimidines. Ultraviolet Spectra and Alkaline Decomposition^1a

1954 • 113 citations

Radiosensitization Of E. Coli by Purine and Pyrimidine Analogues Incorporated in Deoxyribonucleic Acid

1961 • 112 citations

Isolation and properties of isomeric thymine dimers

1966 • 108 citations

Cross-linking of Deoxyribonucleic Acid to Protein following Ultra-Violet Irradiation of Different Cells

1962 • 105 citations

Effects of ultraviolet light on thymidine dinucleotide and polynucleotide

1963 • 102 citations

The Photochemistry of Uridylic Acid

1954 • 96 citations

Photochemistry of the Nucleic Acids

1969 • 91 citations

IDENTIFICATION OF ULTRAVIOLET‐INDUCED THYMINE DIMERS IN DNA BY ABSORBANCE MEASUREMENTS

1963 • 90 citations

The influence of 5-bromodeoxyuridine substitution on UV sensitivity, host-cell reactivation, and photoreactivation in T1 and P22H5

1961 • 86 citations

The action spectrum for the reversal of the dimerization of thymine induced by ultraviolet light

1961 • 81 citations

Effects of ultraviolet light on the template properties of polycytidylic acid

1965 • 79 citations

Thymin-dimerisierung und Überlebensrate bei bakterien

1962 • 75 citations

Photoreactivation of Nucleic Acid from Tobacco Mosaic Virus

1959 • 75 citations

The ultraviolet photochemistry of cytidylyl-(3′-5′)-cytidine

1965 • 74 citations

Kinetics of Thymine Photodimerization in DNA

1963 • 74 citations

Reversal and deamination rates of the main ultraviolet photoproduct of cytidylic acid

1965 • 74 citations

Nuclease-resistant sequences in ultraviolet-irradiated deoxyribonucleic acid

1964 • 72 citations

KINETICS OF DIMER FORMATION AND PHOTOHYDRATION IN ULTRAVIOLET‐IRRADIATED POLYURIDYLIC ACID

1963 • 72 citations

The Photochemistry of Cytidylic Acid

1957 • 72 citations

THE PHOTOCHEMICAL INTERACTION OF DEOXYRIBONUCLEIC ACID AND PROTEIN IN VIVO AND ITS BIOLOGICAL IMPORTANCE*,†

1964 • 70 citations

Genetic transformation studies. II. Radiation sensitivity of halogen labeled DNA

1961 • 69 citations

The biological importance of ultraviolet light induced DNA-protein crosslinks in Escherichia coli 15 TAU

1966 • 68 citations

STUDIES ON THE BIOSYNTHESIS OF BACTERIAL AND VIRAL PYRIMIDINES

1957 • 67 citations

Mechanism of Sensitization to Ultra-Violet Light of T1 Bacteriophage by the Incorporation of 5-Bromodeoxyuridine or by Pre-Irradiation of the Host Cell

1962 • 65 citations

THE PHOTOCHEMISTRY OF THYMINE AND BROMOURACIL IN VIVO

1964 • 65 citations

VARIATION IN THE PHOTOCHEMICAL REACTIVITY OF THYMINE IN THE DNA OF B. SUBTILIS SPORES, VEGETATIVE CELLS AND SPORES GERMINATED IN CHLORAMPHENICOL*,†

1966 • 64 citations

STUDIES ON MECHANISM OF REPAIR OF ULTRAVIOLET-IRRADIATED VIRAL AND BACTERIAL DNA IN VIVO AND IN VITRO

1965 • 62 citations

ULTRAVIOLET IRRADIATION OF PYRIMIDINE DERIVATIVES: II. NOTE ON THE SYNTHESIS OF THE PRODUCT OF REVERSIBLE PHOTOLYSIS OF URACIL

1958 • 62 citations

Correlation of bacterial radiosensitivity and DNA base composition

1962 • 57 citations

Shape of Ultra-violet Inactivation Curves of Transforming Deoxyribonucleic Acid

1960 • 56 citations

Absorption spectra, structure and behaviour towards some enzymes of dihydropyrimidines and dihydro-oligonucleotides.

1960 • 55 citations

Photochemische reaktionen von uracil und uridin

1961 • 53 citations

A comparison of the ultraviolet-light inactivation of infectious ribonucleic acid preparations from tobacco mosaic virus with those of the native and reconstituted virus

1960 • 51 citations

A chemical basis for the sensitization of bacteria to ultraviolet light by incorporated bromouracil

1961 • 49 citations

The resistance of Micrococcus radiodurans to ultraviolet radiation II. Action spectra for killing, delay in DNA synthesis, and thymine dimerization

1965 • 48 citations

The action of radiation on dry desoxyribonucleic acid

1954 • 47 citations

Strahlenchemische Veränderungen von Thymin und Cytosin in der DNS durch UV-Licht

1962 • 45 citations

STUDIES ON THE INACTIVATION OF TOBACCO MOSAIC VIRUS BY ULTRAVIOLET LIGHT*,‡,§

1966 • 45 citations

PHOTOCHEMISTRY OF MODEL OLIGO‐ AND POLYNUCLEOTIDES—IV. HETERO‐OLIGONUCLEOTIDES AND HIGH MOLECULAR WEIGHT SINGLE AND TWIN‐STRANDED POLYMER CHATNS.*†

1962 • 44 citations

Relative stability to thermal denaturation of deoxyribonucleic acid (DNA) preparations containing bromodeoxyuridine

1961 • 43 citations

PROPERTIES OF AN UNUSUAL PHOTOPRODUCT OF U.V. IRRADIATED THYMIDYLYL‐THYMIDINE

1965 • 43 citations

Ultraviolet Damage to Bacteria and Bacteriophage at Low Temperatures

1965 • 42 citations

The UV-induced triplet state in DNA.

1965 • 42 citations

PHOTOCHEMISTRY OF THYMINE IN AQUEOUS SOLUTION*

1965 • 42 citations

Über die strahlensensibilisierende wirkung des 5-bromuracils

1961 • 42 citations

THE EFFECTS OF ULTRAVIOLET-IRRADIATED POLYURIDYLIC ACID IN CELL-FREE PROTEIN SYNTHESIS IN ESCHERICHIA COLI, II. THE INFLUENCE OF SPECIFIC PHOTOPRODUCTS

1963 • 41 citations

Suppression by cysteamine of radiosensitization in 5-bromodeoxyuridine substituted phage T1

1963 • 41 citations

THE EFFECTS OF ULTRAVIOLET-IRRADIATED POLYURIDYLIC ACID IN CELL-FREE PROTEIN SYNTHESIS IN E. COLI

1962 • 39 citations

STUDIES ON THE BIOSYNTHESIS OF BACTERIAL AND VIRAL PYRIMIDINES

1957 • 38 citations

Influence of water content on uv-induced s-mutation and killing in

1956 • 37 citations

DIFFERENTIAL STABILITIES OF INDIVIDUAL HEREDITY DETERMINANTS IN TRANSFORMING PRINCIPLE

1957 • 35 citations

THE ULTRAVIOLET PHOTOCHEMISTRY OF DEOXYURIDYLYL (3′→5′) DEOXYURIDINE

1963 • 35 citations

β-Galactosidase: Inactivation of Its Messenger RNA by Ultraviolet Irradiation

1964 • 35 citations

Sur le mécanisme de la photodimérisation de la thymine

1964 • 32 citations

Physical and biological studies on transforming DNA

1964 • 32 citations

Photochemistry of iodouracil. II Effects of sulfur compounds, ethanol and oxygen

1965 • 31 citations

INACTIVATTON OF S‐RNA BY ULTRAVIOLET RADIATIONS

1964 • 29 citations

Ultraviolett-inaktivierung der phenylalanin- und lysinspezifischen Transfer-Ribonucleinsäuren

1965 • 28 citations

Absence of Photoreactivation in T1 Bacteriophage Irradiated with Ultraviolet in the Dry State

1952 • 28 citations

The role of purine and pyrimidine bases and their analogues in radiation sensitivity

1964 • 26 citations

Effects of Ultra-Violet Light on Hydrogen Bonds in Deoxyribonucleic Acid of Phage T1

1960 • 26 citations

Photochemistry of model oligo- and polynucleotides VI. Photodimerization and its reversal in thymine dinucleotide analogues

1962 • 25 citations

Aggregation and Staining Behaviour of Ultra-violet Irradiated Films of Nucleic Acids

1960 • 21 citations

π‐ELECTRON PHOTOCHEMISTRY OF DL‐PHENYLALANINE IN OXYGEN SATURATED AND OXYGEN FREE SOLUTIONS*

1965 • 20 citations

ON THE PHOTOCHEMISTRY OF THE DINUCLEOTIDE TpC*

1964 • 19 citations

Photoreactivation of UV-damage in phage containing 5-Bromouracil-DNA

1964 • 18 citations

Electron paramagnetic resonance and phosphorescence measurements of the triplet state of orotic acid and related pyrimidines

1965 • 13 citations

The effect of temperature on the cross-linking of deoxyribonucleic acid strands by ultraviolet radiation

1962 • 12 citations

Role of cytosine photoproducts in ultraviolet inactivation of bacteriophage T1

1964 • 12 citations

STUDIES ON THE MECHANISM OF RADIATION INACTIVATION OF MICRO-ORGANISMS—IX. MECHANISM OF THE ULTRAVIOLET-INDUCED INACTIVATION OF TRANSFORMING DEOXYRIBONUCLEIC ACID

1962 • 11 citations

THE ENZYMATIC DEGRADATION OF ULTRAVIOLET‐IRRADIATED DEOXYRIBONUCLEIC ACID*

1966 • 10 citations

INFLUENCE OF pH AND OXYGEN ON 315 mμ INACTIVATION AND THYMINE DIMERIZATION IN MUTANTS OF BACTERIOPHAGE T4

1965 • 9 citations

Influence of cysteine on the photochemical decomposition of thymidyl-(5′-3′)-bromodeoxyuridine

1964 • 7 citations

Effect of Ultraviolet Light on the Biosynthesis of Polyphenylalanine

1962 • 6 citations

Increased Sensitivity in the Detection of Adenine and Pyridine Nucleotides by Exposure to Ultraviolet Light at Low Temperature

1965 • 4 citations