Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 • 1,588 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

1991 • 520 citations

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

1987 • 514 citations

Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.

1986 • 433 citations

Light-chain phosphorylation controls the conformation of vertebrate non-muscle and smooth muscle myosin molecules

1983 • 393 citations

Experimental modulation of occluding junctions in a cultured transporting epithelium.

1980 • 375 citations

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.

1991 • 310 citations

Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells

1992 • 280 citations

Capping of surface receptors and concomitant cortical tension are generated by conventional myosin

1989 • 274 citations

Involvement of myosin light-chain kinase in endothelial cell retraction.

1990 • 249 citations

Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance.

1988 • 238 citations

Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters

1987 • 216 citations

Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro.

1982 • 157 citations

Occluding Junctions in MDCK Cells: Modulation of Transepithelial Permeability by the Cytoskeleton

1982 • 114 citations

Na and Cl transport across the isolated turtle colon: Parallel pathways for transmural ion movement

1977 • 107 citations

Myosin phosphorylation/dephosphorylation and regulation of airway smooth muscle contractility

1991 • 104 citations

Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells.

1981 • 89 citations

An increase or a decrease in myosin II phosphorylation inhibits macrophage motility.

1991 • 76 citations

Extracellular ATP, intracellular calcium and canalicular contraction in rat hepatocyte doublets

1991 • 73 citations

Definition of the inhibitory domain of smooth muscle myosin light chain kinase by site-directed mutagenesis

1991 • 50 citations

Purification and characterization of platelet myosin

1992 • 40 citations

Vasopressin and A23187 stimulate phosphorylation of myosin light chain-1 in isolated rat hepatocytes

1991 • 34 citations

Regulation of embryonic smooth muscle myosin by protein kinase C.

1988 • 33 citations

Fibroblast Contractility without an Increase in Basal Myosin Light Chain Phosphorylation in Wild Type Cells and Cells Expressing the Catalytic Domain of Myosin Light Chain Kinase

1995 • 31 citations

Myosin light chain phosphorylation does not increase during yeast phagocytosis by macrophages

1993 • 27 citations

Ionic permeability of epithelial tissues

1976 • 19 citations