Increased thermal stability of proteins in the presence of amino acids

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Living with Water Stress: Evolution of Osmolyte Systems

1982 • 3,735 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Protein Denaturation

1968 • 2,108 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

Affinities of amino acid side chains for solvent water

1981 • 846 citations

Appendix—Spectrum of horse-heart cytochrome c

1959 • 802 citations

Preferential interactions of proteins with salts in concentrated solutions

1982 • 686 citations

Surface tension of amino acid solutions: A hydrophobicity scale of the amino acid residues

1974 • 456 citations

Increased thermal stability of proteins in the presence of naturally occurring osmolytes

1992 • 437 citations

The Solubility of Amino Acids, Diglycine, and Triglycine in Aqueous Guanidine Hydrochloride Solutions

1970 • 352 citations

Partial specific volumes and interactions with solvent components of proteins in guanidine hydrochloride

1974 • 334 citations

Cotranslational processing and protein turnover in eukaryotic cells

1988 • 201 citations

Hydration and heat stability effects on protein unfolding

1993 • 194 citations

Thermostability of enzymes

1993 • 179 citations

Thermodynamic characterization of cytochrome c at low pH

1992 • 153 citations

Glycerol as an Enzyme-Stabilizing Agent: Effects on Aldehyde Dehydrogenase

1972 • 128 citations

THE MITOTIC APPARATUS

1965 • 114 citations

The stabilization of calf-brain microtubule protein by sucrose

1972 • 114 citations

Microcalorimetric studies of conformational transitions of ferricytochrome c in acidic solution

1989 • 73 citations

Octopine as an End Product of Anaerobic Glycolysis in the Chambered Nautilus

1977 • 70 citations

The unfolding of the cytochromes c in methanol and acid.

1978 • 54 citations

Multifrequency calorimetry of the folding/unfolding transition of cytochrome c

1991 • 21 citations

A New Method for Testing the Functional Dependence of Unfolding Free Energy Changes on Denaturant Concentration1

1994 • 20 citations