Neuroprotective and memory-related actions of novel alpha-7 nicotinic agents with different mixed agonist/antagonist properties.

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Introduction to Statistical Analysis.

1957 • 5,236 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

1989 • 405 citations

Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors

1991 • 315 citations

An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the α7 subtype

1996 • 278 citations

Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin.

1986 • 262 citations

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

1994 • 246 citations

Nicotine-induced protection of cultured cortical neurons againstN-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

1994 • 240 citations

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

1995 • 203 citations

Synaptic Currents Generated by Neuronal Acetylcholine Receptors Sensitive to α-Bungarotoxin

1996 • 189 citations

Nicotine inhibition of apoptosis suggests a role in tumor promotion

1993 • 177 citations

Acute and chronic nicotine effects on working memory in aged rats

1996 • 153 citations

Nicotinic α7 receptors protect against glutamate neurotoxicity and neuronal ischemic damage

1998 • 142 citations

The kinetic properties of neuronal nicotinic receptors: Genetic basis of functional diversity

1993 • 130 citations

A nicotinic agonist (GTS-21), eyeblink classical conditioning and nicotinic receptor binding in rabbit brain

1994 • 121 citations

Chronic nicotine treatment counteracts the disappearance of tyrosine-hydroxylase-immunoreactive nerve cell bodies, dendrites and terminals in the mesostriatal dopamine system of the male rat after partial hemitransection

1988 • 115 citations

Chapter 1 Raising Xenopus in the Laboratory

1991 • 107 citations

Behavioral impairments after lesions of the nucleus basalis by ibotenic acid and quisqualic acid

1991 • 106 citations

Effects of anabaseine‐related analogs on rat brain nicotinic receptor binding and on avoidance behaviors

1994 • 101 citations

Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: Evaluation of the involvement of different neurotransmitter systems

1992 • 80 citations

Cytoprotective actions of 2,4‐dimethoxybenzylidene anabaseine in differentiated PC12 cells and septal cholinergic neurons

1994 • 78 citations

Activation and inhibition of rat neuronal nicotinic receptors by ABT‐418

1997 • 56 citations

Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats

1998 • 45 citations