Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.

Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA

1985 • 762 citations

Identification and characterization of a ouabain-like compound from human plasma.

1991 • 759 citations

Molecular cloning of three distinct forms of the Na+,K+-ATPase .alpha.-subunit from rat brain

1986 • 688 citations

Structure-function relationships in the sodium-potassium ATPase .alpha. subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme

1988 • 403 citations

Primary structure of the α-subunit of Torpedo californica (Na+ + K+)ATPase deduced from cDNA sequence

1985 • 375 citations

Digitalis

1988 • 336 citations

A general method of site-specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction

1989 • 321 citations

Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump.

1988 • 320 citations

Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster.

1989 • 246 citations

Pig kidney Na⁺,K⁺‐ATPase

1986 • 207 citations

Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin

1991 • 193 citations

Structure-function studies of Na,K-ATPase. Site-directed mutagenesis of the border residues from the H1-H2 extracellular domain of the alpha subunit.

1990 • 159 citations

Primary Structure of the α-Subunit of Human Na, K-ATPase Deduced from cDNA Sequence1

1986 • 136 citations

The search for a hypothalamic Na+,K+-ATPase inhibitor.

1987 • 91 citations

Site-directed Mutagenesis of a Conserved, Extracellular Aspartic Acid Residue Affects the Ouabain Sensitivity of Sheep Na,K-ATPase

1989 • 86 citations

Primary sequence of Xenopus laevis Na+-K+-ATPase and its localization in A6 kidney cells

1989 • 63 citations

Coexpression of alpha 1 with putative beta 3 subunits results in functional Na+/K+ pumps in Xenopus oocytes.

1991 • 55 citations

Structure-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. 3. Dissociation rate constants of various enzyme-cardiac glycoside complexes formed in the presence of sodium, magnesium, and adenosine triphosphate.

1974 • 44 citations

Characterization of ouabain-resistant mutants of a canine kidney cell line, MDCK.

1983 • 42 citations

Role of a key cysteine residue in the gating of the acetylcholine receptor

1991 • 41 citations

Association and dissociation rate constants of the complexes between various cardiac aglycones and sodium- and potassium-dependent adenosine triphosphatase formed in the presence of magnesium and phosphate.

1977 • 31 citations

Expression of an ouabain resistance gene in transfected cells. Ouabain treatment induces a K+-transport system.

1985 • 27 citations