Quantitative relationship between anticapsular antibody measured by enzyme-linked immunosorbent assay or radioimmunoassay and protection of mice against challenge with Streptococcus pneumoniae serotype 4

Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae.

1981 • 477 citations

Some Observations on the Pneumococcus and on the Current Status of Pneumococcal Disease and Its Prevention

1981 • 294 citations

A radioimmunoassay for immunologic phenomena in pneumococcal disease and for the antibody response to pneumococcal vaccines. I. Method for the radioimmunoassay of anticapsular antibodies and comparison with other techniques

1980 • 196 citations

Pneumococcal Polysaccharide Vaccine in Young Adults and Older Bronchitics: Determination of IgG Responses by ELISA and the Effect of Adsorption of Serum with Non-Type-Specific Cell Wall Polysaccharide

1990 • 194 citations

Natural and Vaccine-Related Immunity to Streptococcus pneumoniae

1986 • 194 citations

Serum antibodies to pneumococcal C polysaccharide in children

1987 • 153 citations

Interruption of capsule production in Streptococcus pneumonia serotype 3 by insertion of transposon Tn916

1990 • 134 citations

PNEUMONIA IN OLD AGE

1947 • 121 citations

The Role of Antibody and Complement in the Reticuloendothelial Clearance of Pneumococci from the Bloodstream

1983 • 116 citations

Localization of complement component 3 on Streptococcus pneumoniae: anti-capsular antibody causes complement deposition on the pneumococcal capsule

1983 • 114 citations

Surveillance of invasive Streptococcus pneumoniae infection in Quebec, Canada, from 1984 to 1986: serotype distribution, antimicrobial susceptibility, and clinical characteristics

1989 • 108 citations

Ultrastructural localization of capsules, cell wall polysaccharide, cell wall proteins, and F antigen in pneumococci

1988 • 96 citations

Does Naturally Acquired IgG Antibody to Cell Wall Polysaccharide Protect Human Subjects against Pneumococcal Infection?

1990 • 95 citations

Standardization of antibody assays for measuring the response to pneumococcal infection and immunization

1989 • 87 citations

An Endotoxin from Aspergillus Fumigatus

1939 • 84 citations

Blood clearance by anti-phosphocholine antibodies as a mechanism of protection in experimental pneumococcal bacteremia.

1984 • 71 citations

Epidemiological Studies of Streptococcus pneumoniae in Infants: Antibody to Types 3, 6, 14, and 23 in the First Two Years of Life

1988 • 66 citations

C-POLYSACCHARIDE IN A PNEUMOCOCCAL VACCINE

2009 • 65 citations

Protection against pneumococcal infection in mice conferred by phosphocholine-binding antibodies: specificity of the phosphocholine binding and relation to several types

1983 • 64 citations

Response to Pneumococcal Vaccine among Asymptomatic Heterosexual Partners of Persons with AIDS and Intravenous Drug Users Infected with Human Immunodeficiency Virus

1989 • 63 citations

IMMUNOLOGICAL REACTIONS OF THE ISOLATED CARBOHYDRATE AND PROTEIN OF PNEUMOCOCCUS

1925 • 55 citations

Marker discrimination in deoxyribonucleic acid-mediated transformation of various Pneumococcus strains

1975 • 55 citations

Resistance to Streptococcus pneumoniae is induced by a phosphocholine-protein conjugate.

1983 • 49 citations

Binding of C-reactive protein to the pneumococcal capsule or cell wall results in differential localization of C3 and stimulation of phagocytosis.

1984 • 42 citations

Pneumococcal vaccination. Controversies and opportunities.

1990 • 41 citations

RESULTS OF PROPHYLACTIC INOCULATION AGAINST PNEUMOCOCCUS IN 12,519 MEN

1918 • 38 citations

Pneumococcal Vaccination: Work to Date and Future Prospects

1990 • 37 citations

ACTIVE AND PASSIVE IMMUNITY TO PNEUMOCOCCUS INFECTION INDUCED IN RABBITS BY IMMUNIZATION WITH R PNEUMOCOCCI

1928 • 24 citations

IMMUNIZATION OF EXPERIMENTAL ANIMALS WITH A SOLUBLE ANTIGEN EXTRACTED FROM PNEUMOCOCCI

1938 • 18 citations

Prevention of Pneumococcal Bacteremia by Immunization with Type 6 Pneumococcal Capsular Polysaccharide Vaccine in Splenectomized Rats

1989 • 16 citations

Conference on the Pneumococcus: Summary and Comments

1981 • 4 citations