V. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system

Physiology of the Gastrointestinal Tract.

1987 • 1,948 citations

Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

Origins of Cell Polarity

1996 • 1,024 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

Sequential Uptake of Horseradish Peroxidase by Lymphoid Follicle Epithelium of Peyer's Patches in the Normal Unobstructed Mouse Intestine: An Ultrastructural Study

1977 • 673 citations

Conversion by Peyer's Patch Lymphocytes of Human Enterocytes into M Cells that Transport Bacteria

1997 • 625 citations

Epithelial cells as sensors for microbial infection.

1997 • 623 citations

ANTIGEN SAMPLING ACROSS EPITHELIAL BARRIERS AND INDUCTION OF MUCOSAL IMMUNE RESPONSES

1996 • 462 citations

Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting.

1996 • 392 citations

Paneth cell defensins: Endogenous peptide components of intestinal host defense

1996 • 284 citations

Structure, Distribution, and Origin of M Cells in Peyer’s Patches of Mouse Ileum

1984 • 275 citations

Differentiation and self-renewal in the mouse gastrointestinal epithelium

1994 • 256 citations

Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch

1987 • 253 citations

Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

1993 • 242 citations

Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins.

1989 • 235 citations

Uptake and translocation of fluorescent latex particles by rabbit Peyer's patch follicle epithelium: a quantitative model for M cell uptake.

1989 • 222 citations

Differential expression of lectin-binding sites defines mouse intestinal M-cells.

1993 • 219 citations

Transepithelial transport of HIV-1 by intestinal M cells: a mechanism for transmission of AIDS.

1991 • 204 citations

Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin‐binding and anionic sites in rat and mouse Peyer's patch M cells

1983 • 174 citations

M cells and the pathogenesis of mucosal and systemic infections

1996 • 168 citations

Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines

1994 • 153 citations

Lectins are sensitive tools for defining the differentiation programs of mouse gut epithelial cell lineages

1994 • 153 citations

Salmonella-induced M-cell formation in germ-free mouse Peyer's patch tissue.

1991 • 151 citations

Heterogeneity of M-cell-associated B and T cells in human Peyer's patches.

1994 • 121 citations

Rat intestinal M cells contain acidic endosomal-lysosomal compartments and express class II major histocompatibility complex determinants

1993 • 115 citations

Cathepsin E in follicle associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing

1993 • 112 citations

Absence of secretory component expression by epithelial cells overlying rabbit gut-associated lymphoid tissue

1988 • 111 citations

Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells

1995 • 110 citations

Proteolytic processing of reovirus is required for adherence to intestinal M cells

1994 • 110 citations

Mechanisms of viral pathogenesis. Distinct forms of reoviruses and their roles during replication in cells and host.

1991 • 98 citations

Differential distribution of lymphocytes and accessory cells in mouse Peyer's patches

1986 • 94 citations

M cell numbers increase after transfer of SPF mice to a normal animal house environment.

1987 • 94 citations

Mucosal IgA response to rectally administered antigen formulated in IgA-coated liposomes

1995 • 87 citations

Development of dome epithelium in gut-associated lymphoid tissues: Association of IgA with M cells

1987 • 79 citations

Differential binding of lectins to M cells and enterocytes in the rabbit cecum

1993 • 79 citations

Co-localization of vimentin and cytokeratins in M-cells of rabbit gut-associated lymphoid tissue (GALT)

1992 • 77 citations

The Filamentous Brush Border Glycocalyx, a Mucin-like Marker of Enterocyte Hyper-Polarization

1995 • 76 citations

Structure and function of the intestinal epithelial barrier in health and disease.

1990 • 70 citations

Ultrastructural study of liposome uptake by M cells of rat Peyer's patch: an oral vaccine system for delivery of purified antigen.

1990 • 63 citations

MODIFICATIONS OF THE FOLLICLE-ASSOCIATED EPITHELIUM BY SHORT-TERM EXPOSURE TO A NON-INTESTINAL BACTERIUM

1996 • 60 citations

Cytosolic distribution of villin in M cells from mouse Peyer's patches correlates with the absence of a brush border

1996 • 59 citations

A Pathogen-specific Epitope Inserted into Recombinant Secretory Immunoglobulin A Is Immunogenic by the Oral Route

1996 • 55 citations

The Filamentous Brush Border Glycocalyx, a Mucin-like Marker of Enterocyte Hyper-Polarization

1995 • 55 citations

Phenotypically distinct subpopulations of T cells in domes and M-cell pockets of rabbit gut-associated lymphoid tissues.

1990 • 53 citations

Peyer's Patches as Inductive Sites for IgA Commitment

1994 • 46 citations

Dendritic Cells of the Murine Peyer’s Patches Colocalize with Salmonella Typhimurium Avirulent Mutants in the Subepithelial Dome

1997 • 41 citations

Mechanisms of Viral Pathogenesis

1984 • 36 citations

Evidence that Membranous (M) Cell Genesis is Immuno-Regulated

1995 • 34 citations

Regulation of IgA B Cell Development

1994 • 33 citations

Linear arrays of intramembrane particles on microvilli in primate large intestine

1979 • 32 citations

Lymphocyte compartments in antigen-sampling regions of rabbit mucosal lymphoid organs.

1994 • 31 citations

M cells are damaged and increased in number in inflamed human ileal mucosa.

1993 • 29 citations

Structure and Permeability Differ in Subepithelial Villus and Peyer’s Patch Follicle Capillaries

1991 • 28 citations

Unique Features of Antigen Presentation in the Intestinea

1992 • 27 citations

Phenotype and distribution of T lymphocytes in Peyer's patches of athymic mice

1987 • 15 citations

Antigen Uptake by M Cells for Effective Mucosal Vaccines

1996 • 14 citations

Structure and permeability differ in subepithelial villus and peyer's patch follicle capillaries

1991 • 9 citations