Control of proteoglycan synthesis. Studies on the activation of synthesis observed during culture of articular cartilages

A modified uronic acid carbazole reaction

1962 • 6,191 citations

Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips

1970 • 826 citations

Sulphate (35SO4) Uptake by Chondrocytes in Relation to Histological Changes in Osteo-Arthritic Human Articular Cartilage

1960 • 245 citations

The effect of D-xylose, β-D-xylosides and β-D-galactosides on chondroitin sulphate biosynthesis in embryonic chicken cartilage

1975 • 160 citations

The inhibition of sulphate incorporation in isolated adult chondrocytes by hyaluronic acid

1973 • 116 citations

Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture

1976 • 116 citations

Extracellular matrix metabolism by chondrocytes III. Modulation of proteoglycan synthesis by extracellular levels of proteoglycan in cartilage cells in culture

1977 • 116 citations

Changes in the protein–polysaccharides of pig articular cartilage during prenatal life, development and old age

1972 • 112 citations

Anaerobic and aerobic metabolism in articular cartilage.

1977 • 110 citations

Biosynthesis of the Chondroitin Sulfate Proteoglycan

1972 • 101 citations

Biosynthesis of Chondroitin Sulfate Proteoglycan

1972 • 100 citations

Degradation of proteoglycan in articular cartilage

1978 • 92 citations

The Sulfation of Chondroitin Sulfate in Embryonic Chick Cartilage Epiphyses

1969 • 89 citations

Proteoglycans from bovine proximal humeral articular cartilage. Structural basis for the polydispersity of proteoglycan subunit.

1976 • 81 citations

The stability of bovine nasal cartilage proteoglycans during isolation and storage

1977 • 76 citations

Isolation of proteoglycans from human articular cartilage

1978 • 72 citations

The stability of the collagen phenotype during stimulated collagen, glycosaminoglycan, and DNA synthesis by articular cartilage organ cultures

1979 • 71 citations

Glycosaminoglycan Metabolism in Experimental Osteoarthrosis Caused by Immobilization

1978 • 68 citations

The molecular-weight distribution of glycosaminoglycans

1973 • 66 citations

Replacement of proteoglycans in embryonic chick cartilage in organ culture after treatment with testicular hyaluronidase

1972 • 64 citations

Environmental control of macromolecular synthesis in cartilage and bone: morphogenetic response to hyaluronidase

1970 • 61 citations

Biosynthesis of chondroitin sulfate. Purification of UDP-d-xylose:core protein β-d-xylosyltransferase by affinity chromatography

1974 • 61 citations

The alkaline cleavage and borohydride reduction of cartilage proteoglycan

1973 • 55 citations

Antigen‐induced arthritis. decreased proteoglycan content and inhibition of proteoglycan synthesis in articular cartilage

1978 • 51 citations

Biochemical and metabolic abnormalities in osteoarthritic human cartilage.

1973 • 51 citations

The effect of β-<scp>d</scp>-xylosides on chondroitin sulphate biosynthesis in embryonic chicken cartilage in the absence of protein synthesis inhibitors

1977 • 43 citations

Characterization of the collagen synthesized by cultured cartilage cells

1975 • 42 citations

Cellular control of macromolecular synthesis: rates of synthesis of extracellular macromolecules during and after depletion by papain

1968 • 41 citations

Fluorimetric Determination of DNA in Papain Digests of Cartilage, Using Ethidium Bromide

1979 • 35 citations

Biosynthesis of chondroitin sulfate: Immunoprecipitation of interacting xylosyltransferase and galactosyltransferase

1975 • 34 citations

Chondroitin sulfate glycosyltransferases in cultured chondrocytes. Turnover, oscillatory change during growth, and suppression by 5-bromodeoxyuridine.

1976 • 30 citations

Pig articular cartilage in organ culture. Effect of enzymatic depletion of the matrix on response of chondrocytes to complement-sufficient antiserum against pig erythrocytes.

1974 • 29 citations

In vitro rabbit articular cartilage organ model I. Morphology and glycosaminoglycan metabolism

1974 • 28 citations

The effect of temperature on the biosynthesis of chondroitin 4‐sulphate in cartilage slices in vitro

1970 • 19 citations

The assay of xylosyltransferase in cartilage extracts. A modified procedure for preparation of Smith-degraded proteoglycan

1979 • 19 citations

Effects of medium composition and metabolic inhibitors on glycosaminoglycan synthesis in chick embryo cartilage and its stimulation by serum and triiodothyronine

1976 • 15 citations

Studies on the in vitro incubation procedure for [35]sulphate labelling of articular cartilage glycosaminoglycans

1977 • 5 citations

Increased metabolic activity of rabbit articular cartilage in vitro

1978 • 2 citations