Leptin depolarizes rat hypothalamic paraventricular nucleus neurons

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1995 • 3,730 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

1995 • 1,630 citations

Leptin enters the brain by a saturable system independent of insulin

1996 • 1,210 citations

Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior.

1985 • 731 citations

Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity.

1995 • 573 citations

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting.

1996 • 552 citations

Paraventricular nucleus: A primary site mediating adrenergic stimulation of feeding and drinking

1978 • 441 citations

Leptin Activates Neurons in Ventrobasal Hypothalamus and Brainstem

1997 • 428 citations

Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels.

1997 • 374 citations

Hypothalamic paraventricular nucleus lesions produce overeating and obesity in the rat

1981 • 371 citations

Brain monoamines and peptides: role in the control of eating behavior.

1986 • 253 citations

Electrophysiological properties of neurones in the region of the paraventricular nucleus in slices of rat hypothalamus.

1991 • 232 citations

Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus.

1996 • 176 citations

Microelectrophoresis of cholinergic and aminergic drugs on paraventricular neurons

1972 • 174 citations

Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain

1996 • 173 citations

Expression of leptin receptor mRNA in the hypothalamic arcuate nucleus - relationship with NPY neurones

1996 • 164 citations

Paraventricular area: Critical focus of a longitudinal neurocircuitry mediating food intake

1977 • 163 citations

Localization of leptin receptor mRNA expression in mouse brain

1996 • 159 citations

Nitric oxide regulates NMDA‐driven GABAergic inputs to type I neurones of the rat paraventricular nucleus.

1997 • 159 citations

GABA and hypothalamic feeding systems. I. Topographic analysis of the effects of microinjections of muscimol

1979 • 97 citations

Morphine and opioid peptides reduce paraventricular neuronal activity: studies on the rat hypothalamic slice preparation.

1980 • 94 citations

Paraventricular hypothalamic lesions and medial hypothalamic knife cuts produce similar hyperphagia syndromes.

1983 • 85 citations

Hyperphagia and obesity produced by parasagittal and coronal hypothalamic knife cuts: Further evidence for a longitudinal feeding inhibitory pathway.

1977 • 82 citations

Paraventricular hypothalamic lesions and medial hypothalamic knife cuts produce similar hyperphagia syndromes.

1983 • 80 citations

Hypothalamic sites sensitive to morphine and naloxone: Effects on feeding behavior

1985 • 79 citations

EXPERIMENTAL OBESITY IN THE DOG

1944 • 54 citations

A 35 amino acid fragment of leptin inhibits feeding in the rat.

1996 • 51 citations

GABA and hypothalamic feeding systems

1980 • 42 citations