Intravascular oxygen distribution in subcutaneous 9L tumors and radiation sensitivity

Radiobiology for the Radiologist.

1974 • 3,582 citations

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1989 • 3,308 citations

On Respiratory Impairment in Cancer Cells

1956 • 2,963 citations

The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in Radiotherapy

1953 • 2,102 citations

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

1988 • 811 citations

Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data

1984 • 610 citations

An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence.

1987 • 592 citations

Imaging of Phosphorescence: A Novel Method for Measuring Oxygen Distribution in Perfused Tissue

1988 • 526 citations

Regulation of cellular energy metabolism

1982 • 433 citations

Definitive evidence for hypoxic cells influencing cure in cancer therapy.

1978 • 422 citations

The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration.

1988 • 374 citations

The oxygen dependence of cellular energy metabolism

1979 • 360 citations

RADIOTHERAPY AND HYPERBARIC OXYGEN IN HEAD AND NECK CANCER

1977 • 321 citations

Tumor tissue oxygenation as evaluated by computerized-po2-histography

1990 • 255 citations

Calibration of Oxygen-Dependent Quenching of the Phosphorescence of Pd-meso-tetra (4-Carboxyphenyl) Porphine: A Phosphor with General Application for Measuring Oxygen Concentration in Biological Systems

1996 • 244 citations

Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cells.

1983 • 187 citations

Measurement of regional cerebral blood flow and oxygen utilisation in patients with cerebral tumours using 15O and positron emission tomography: Analytical techniques and preliminary results

1982 • 185 citations

Blood flow, oxygen consumption, and tissue oxygenation of human breast cancer xenografts in nude rats.

1987 • 183 citations

Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide]: analysis of drug adducts by fluorescent antibodies vs bound radioactivity

1995 • 181 citations

Noninvasive imaging of the distribution in oxygen in tissue in vivo using near-infrared phosphors

1996 • 179 citations

Quantitative dependence of mitochondrial oxidative phosphorylation on oxygen concentration: A mathematical model

1979 • 168 citations

Effect of hyperventilation on oxygenation of the brain cortex of newborn piglets

1991 • 134 citations

Localization of tumors and evaluation of their state of oxygenation by phosphorescence imaging.

1992 • 92 citations

The effect on the Km for radiosensitization at 0 degree C of thiol depletion by diethylmaleate pretreatment: quantitative differences found using the radiation sensitizing agent misonidazole or oxygen.

1984 • 83 citations

Cellular radiosensitivity of a rat brain tumor

1975 • 74 citations

Utilization of oxygen by transplanted tumors in vivo.

1967 • 69 citations

Oxygen dependence of binding of misonidazole to rodent and human tumors in vitro.

1987 • 66 citations

Evidence for an Unconventional Radiosensitivity of Rat 9L Subcutaneous Tumors

1980 • 63 citations

Metabolism induced binding of 4C-misonidazole to hypoxic cells: Kinetic dependence on oxygen concentration and misonidazole concentration

1984 • 62 citations

The Effect on the K m for Radiosensitization at 0 degrees C of Thiol Depletion by Diethylmaleate Pretreatment: Quantitative Differences Found Using the Radiation Sensitizing Agent Misonidazole or Oxygen

1984 • 58 citations

Effect of Oxygen Concentration on Cellular Metabolism

1985 • 54 citations

Hyperbaric oxygen in radiation therapy. An investigation of dose-effect relationships in tumor response and tissue damage.

1968 • 50 citations

Intracapillary HbO2 saturation in malignant tumors during normoxia and hyperoxia

1979 • 48 citations

HYPERBARIC OXYGEN IN RADIATION THERAPY

1968 • 47 citations

The Effect of Alterations in Haematocrit on Tumour Sensitivity to X-rays

1984 • 40 citations

Is cell survival a determinant of the in situ response of 9L tumours?

1980 • 35 citations

Distribution of misonidazole adducts in 9L gliosarcoma tumors and spheroids: implications for oxygen distribution.

1992 • 16 citations

O2 Supply Conditions in Tumor Tissue in Vivo

1976 • 14 citations

Comparative measurement of Regional blood flow, oxygen and glucose utilisation in soft tissue tumour of rabbit with positron imaging

1985 • 13 citations