Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

The Synaptic Organization of the Brain

2004 • 3,543 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Distinguishing theoretical synaptic potentials computed for different soma-dendritic distributions of synaptic input.

1967 • 1,003 citations

Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

1987 • 934 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

Regulation of brain Type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: A Ca2+-triggered molecular switch

1986 • 856 citations

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

1988 • 747 citations

Time Constants and Electrotonic Length of Membrane Cylinders and Neurons

1969 • 746 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

1985 • 609 citations

Synapses as associative memory elements in the hippocampal formation

1979 • 573 citations

Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus

1975 • 501 citations

Patterns of activation in a monosynaptic cortical pathway: The perforant path input to the dentate area of the hippocampal formation

1971 • 473 citations

A mechanism for memory storage insensitive to molecular turnover: a bistable autophosphorylating kinase.

1985 • 470 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

1987 • 420 citations

The action of N‐methyl‐D‐aspartic acid on mouse spinal neurones in culture.

1985 • 417 citations

Frequency-dependent involvement of NMDA receptors in the hippocampus: a novel synaptic mechanism

1986 • 416 citations

Slow excitatory postsynaptic currents mediated by N‐methyl‐D‐aspartate receptors on cultured mouse central neurones.

1988 • 364 citations

Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics

1988 • 316 citations

Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction.

1985 • 305 citations

Associative long-term potentiation in hippocampal slices.

1983 • 280 citations

Synaptic activation of N‐methyl‐D‐aspartate receptors in the Schaffer collateral‐commissural pathway of rat hippocampus.

1988 • 277 citations

The process of reinnervation in the dentate gyrus of the adult rat: A quantitative electron microscopic analysis of terminal proliferation and reactive synaptogenesis

1983 • 252 citations

Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities.

1984 • 238 citations

Quisqualate Activates a Rapidly Inactivating High Conductance Ionic Channel in Hippocampal Neurons

1989 • 237 citations

N‐methyl‐D‐aspartate‐activated channels of mouse central neurones in magnesium‐free solutions.

1988 • 230 citations

Glutamate as transmitter of hippocampal perforant path

1977 • 227 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

Presence of calmodulin in postsynaptic densities isolated from canine cerebral cortex.

1979 • 208 citations

The Dynamics of Free Calcium in Dendritic Spines in Response to Repetitive Synaptic Input

1987 • 205 citations

Passive electrical constants in three classes of hippocampal neurons

1981 • 196 citations

The time course of minimal excitatory post‐synaptic potentials evoked in spinal motoneurones by group la afferent fibres

1971 • 194 citations

Synaptic efficacy and EPSP summation in granule cells of rat fascia dentata studied in vitro.

1981 • 180 citations

Hippocampal long-lasting potentiation produced by pairing single volleys and brief conditioning tetani evoked in separate afferents

1986 • 174 citations

l-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis

1985 • 170 citations

Calcium-induced long-term potentiation in the hippocampus

1982 • 170 citations

Electrophysiology of dentate gyrus granule cells

1984 • 164 citations

The Calcium Pump and Sodium-Calcium Exchange in Squid Axons

1983 • 160 citations

Calcium binding to complexes of calmodulin and calmodulin binding proteins

1985 • 152 citations

On long‐lasting potentiation in the hippocampus. a proposed mechanism for its dependence on coincident pre‐ and postsynaptic activity

1985 • 136 citations

Quantitative autoradiography of binding sites for [3H]AMPA, a structural analogue of glutamic acid

1984 • 135 citations

The function of dendritic spines: A review of theoretical issues

1985 • 133 citations

A possible correlate of the postsynaptic condition for long-lasting potentiation in the guinea pig hippocampus in vitro

1984 • 129 citations

A quantitative anatomical study of the granule cell dendritic fields of the rat dentate gyrus using a novel probabilistic method

1982 • 107 citations

CHARACTERIZATION OF PUTATIVE AMINO ACID TRANSMITTER RELEASE FROM SLICES OF RAT DENTATE GYRUS

1977 • 107 citations

Quantitative methods for predicting neuronal behavior

1981 • 100 citations

The role of dendritic diameters in maximizing the effectiveness of synaptic inputs

1989 • 75 citations

Activity-dependent accumulation of calcium in Purkinje cell dendritic spines.

1988 • 71 citations

THE PRESENCE AND FUNCTIONS OF CALMODULIN IN THE POSTSYNAPTIC DENSITY

1980 • 64 citations

Changes in translation of synaptic excitation to dentate granule cell discharge accompanying long-term potentiation. I. Differences between normal and reinnervated dentate gyrus.

1981 • 54 citations

Cooperativity among afferents for the induction of long-term potentiation in the CA1 region of the hippocampus

1983 • 53 citations

Activation of receptors contributes to the EPSP at perforant path synapses in the rat dentate gyrus in vitro

1989 • 46 citations

The ins and outs of calcium transport in squid axons: internal and external ion activation of calcium efflux.

1976 • 44 citations

A synaptic potential following single volleys in the hippocampal CA1 region possibly involved in the induction of long‐lasting potentiation

1985 • 42 citations

Dendritic caliber and the 3/2 power relationship of dentate granule cells

1984 • 29 citations

A continuous cable method for determining the transient potential in passive dendritic trees of known geometry

1986 • 28 citations

Habituation-like decrements in transmission along the normal and lesion-induced temporodentate pathways in the rat

1978 • 22 citations

Rate‐limiting step for transmission at excitatory synapses in hippocampus

1989 • 14 citations

Solution of large compartmental models using numerical transform inversion

1987 • 2 citations