Thyroid Hormone–Carbohydrate Interaction

Tissue Differences in the Concentration of Triiodothyronine Nuclear Binding Sites in the Rat: Liver, Kidney, Pituitary, Heart, Brain, Spleen and Testis

1974 • 469 citations

Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.

1977 • 342 citations

Mechanisms and regulation of biosynthesis of saturated fatty acids.

1976 • 340 citations

Futile Cycles in the Metabolism of Glucose

1976 • 322 citations

Iodothyronine Metabolism in Rat Liver Homogenates

1978 • 315 citations

Extent and Patterns of Adaptation of Enzyme Activities in Livers of Normal Rats Fed Diets High in Glucose and Fructose

1960 • 312 citations

Dietary-induced alterations in thyroid hormone metabolism during overnutrition.

1979 • 306 citations

A preliminary investigation of the hormonal control of the hexose monophosphate oxidative pathway

1955 • 281 citations

EFFECT OF CALORIC RESTRICTION AND DIETARY COMPOSITION ON SERUM T₃AND REVERSE T₃IN MAN

1976 • 273 citations

The Effect of Starvation on the Concentration and Binding of Thyroxine and Triiodothyronine in Serum and on the Response to TRH

1974 • 256 citations

Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes.

1979 • 251 citations

Effect of Tri-Iodothyronine Replacement on the Metabolic and Pituitary Responses to Starvation

1979 • 235 citations

Patterns of dietary and hormonal induction of certain NADP-linked liver enzymes

1964 • 206 citations

Effect of thyroid hormones on the level of the hepatic mRNA for α_2u globulin

1976 • 201 citations

Pathways of glucose catabolism in rat liver in alloxan diabetes and hyperthyroidism

1956 • 186 citations

Synthesis and degradation of the lipogenic enzymes of rat liver

1972 • 186 citations

The Concentration of Malonyl-Coenzyme A and the Control of Fatty Acid Synthesis in Vivo

1972 • 182 citations

Rapid Effects of Single Small Doses of L-Thyroxine and Triiodo-L-thyronine on Growth Hormone, as Studied in the Rat by Radioimmunoassay¹

1975 • 177 citations

Enzyme Activities Related to Fatty‐Acid Synthesis in Liver and Adipose Tissue of Rats Treated with Triiodothyronine

1972 • 169 citations

Thyroid and glucocorticoid hormones synergistically control growth hormone mRNA in cultured GH1 cells.

1978 • 169 citations

Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level.

1981 • 164 citations

Changes in the hepatic levels of messenger ribonucleic acid for malic enzyme during induction by thyroid hormone or diet

1980 • 160 citations

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.

1977 • 151 citations

Synergism of thyroid hormone and high carbohydrate diet in the induction of lipogenic enzymes in the rat. Mechanisms and implications.

1980 • 149 citations

Regulation of hepatic acetyl coenzyme A carboxylase by insulin and glucagon.

1979 • 147 citations

Effects of thyroid hormones on enzymes involved in fatty acid and glycerolipid synthesis

1975 • 139 citations

Effect of age on glucose-stimulated insulin release by the beta-cell of the rat.

1979 • 135 citations

Regulation of Fatty Acid Synthesis in Isolated Hepatocytes Prepared from the Livers of Neonatal Chicks

1973 • 124 citations

Opposite Effects of Insulin and Glucagon in Acute Hormonal Control of Hepatic Lipogenesis

1979 • 121 citations

Fatty acid synthetase activity in the liver and adipose tissue of rats fed with various carbohydrates

1972 • 121 citations

Fasting Decreases Triiodothyronine Receptor Capacity

1978 • 120 citations

Metabolism of glucose in hyper- and hypo-thyroid rats in vivo. Glucose-turnover values and futile-cycle activities obtained with 14C- and 3H-labelled glucose

1979 • 117 citations

¹³ C NMR studies of gluconeogenesis in rat liver cells: Utilization of labeled glycerol by cells from euthyroid and hyperthyroid rats

1979 • 115 citations

Influence of Thyroid Status on Lipid Metabolism in the Perfused Rat Liver

1979 • 110 citations

Effect of starvation on hypothalamic-pituitary-thyroid function in the rat

1978 • 110 citations

Reduction in Hepatic Triiodothyronine Binding Capacity Induced by Fasting

1977 • 104 citations

Effects of Oral and Intravenous Glucose Loading in Thyrotoxicosis: Studies of Plasma Glucose, Free Fatty Acid, Plasma Insulin and Blood Pyruvate Levels

1969 • 103 citations

Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism

1977 • 99 citations

Regulation of the d-glucose transport system in isolated fat cells

1976 • 99 citations

The Role of Sulfhydryl Groups on the Impaired Hepatic 3′,3,5-Triiodothyronine Generation from Thyroxine in the Hypothyroid, Starved, Fetal, and Neonatal Rodent

1979 • 98 citations

Glucose and triiodothyronine both induce malic enzyme in the rat hepatocyte culture: evidence that triiodothyronine multiplies a primary glucose-generated signal.

1981 • 90 citations

Nonlinear (amplified) relationship between nuclear occupancy by triiodothyronine and the appearance rate of hepatic alpha-glycerophosphate dehydrogenase and malic enzyme in the rat.

1978 • 89 citations

Starvation-Induced Decreased Sensitivity of Resting Metabolic Rate to Triiodothyronine

1979 • 88 citations

Abnormalities of Thyroid Hormone Turnover in Patients with Diabetes Mellitus before and after Insulin Therapy*

1979 • 84 citations

Glucose modulation of alterations in serum iodothyronine concentrations induced by fasting

1979 • 83 citations

Effects of Thyroid Function upon Insulin Secretion

1967 • 82 citations

Effect of Carbohydrate and Noncarbohydrate Sources of Calories on Plasma 3,5,3′-Triiodothyronine Concentrations in Man*

1979 • 82 citations

Hormonal Control of Hepatic Gluconeogenesis

1979 • 80 citations

The Role of Thyroid Function in the Metabolism of Perfused Rat Liver with Particular Reference to Gluconeogenesis

2005 • 79 citations

Regulation of Mammalian Fatty-Acid Synthetase. The Roles of Carbohydrate and Insulin

1974 • 78 citations

Effects of Thyroid Hormone Deficiency on the Distribution of Hepatic Metabolites and Control of Pathways of Carbohydrate Metabolism in Liver and Adipose Tissue of the Rat

1976 • 78 citations

Effect of Thyroid Status on Insulin Action in Rat Adipocytes and Skeletal Muscle

1980 • 78 citations

Rat liver glucose-6-p dehydrogenase. Dietary regulation of the rate of synthesis.

1977 • 76 citations

The concurrent induction of hepatic alpha-glycerophosphate dehydrogenase and malate dehydrogenase by thyroid hormone.

1966 • 74 citations

Quantitation of rat liver messenger ribonucleic acid for malic enzyme during induction by thyroid hormone

1981 • 73 citations

Carbohydrate metabolism in its relation to the thyroid gland.—The effect of thyroid feeding on the glycogen-content of the liver and on the nitrogen distribution in the urine

1913 • 70 citations

Fluctuation of Hepatic Enzymes Important in Glucose Metabolism in Relation to Thyroid Function

1970 • 69 citations

Effect of Age and Weight on Plasma Glucose and Insulin Responses in the Rat†

1977 • 67 citations

Selective alterations in hepatic enzyme response after reduction of nuclear triiodothyronine receptor sites by partial hepatectomy and starvation

1978 • 66 citations

Role of growth hormone in the multihormonal regulation of messenger RNA for α_2u globulin in the liver of hypophysectomized rats

1977 • 65 citations

The concurrent induction of hepatic α-glycerophosphate dehydrogenase and malate dehydrogenase by thyroid hormone

1966 • 58 citations

GLUCOSE AND FREE FATTY ACID TURNOVER IN THYROTOXICOSIS AND HYPOTHYROIDISM, BEFORE AND AFTER TREATMENT

1980 • 58 citations

THE GLUCOSE MOBILIZATION RATE IN HYPERTHYROIDISM

1922 • 58 citations

Comparison of the Response Characteristics of Four Lipogenic Enzymes to 3,5,3′-Triiodothyronine Administration: Evidence for Variable Degrees of Amplification of the Nuclear 3,5,3′-Triiodothyronine Signal*

1980 • 58 citations

GLUCOSE TOLERANCE AND INSULIN SECRETION IN HYPERTHYROIDISM

1977 • 56 citations

INFLUENCE OF THYROID FUNCTION ON CARBOHYDRATE METABOLISM AND A NEW METHOD FOR ASSESSING RESPONSE TO INSULIN

1961 • 56 citations

SERUM TRIIODOTHYRONINE IN UNDERNOURISHED RATS: DEPENDENCE ON DIETARY COMPOSITION RATHER THAN TOTAL CALORIE OR PROTEIN INTAKE

1978 • 56 citations

Specificity of the α-Glycerophosphate Dehydrogenase and Malic Enzyme Response to Thyroxine

1965 • 55 citations

On the Relationship between Fatty Acid Synthesis and the Total Activities of Acetyl Coenzyme A Carboxylase and Fatty Acid Synthetase in the Liver of Prenatal and Early Postnatal Chicks

1973 • 54 citations

Carbohydrate metabolism in hypothyroid myopathy

1977 • 54 citations

Effects of thyroid states on the Cori cycle, glucose-alanine cycle, and futile cycling of glucose metabolism in rats

1981 • 52 citations

Influence of hyperthyroidism on splanchnic exchange of glucose and gluconeogenic precursors.

1981 • 52 citations

Rapid and direct stimulation of hepatic gluconeogenesis by L-triiodothyronine (T3) in the isolated-perfused rat liver

1980 • 50 citations

Factors Determining the Level of Activity of 3,5,3- Triiodothyronine-Responsive Hepatic Enzymes in the Starved Rat*

1980 • 49 citations

The Effect of Epinephrine, Insulin, and Hyperthyroidism on the Rapid Intravenous Glucose Tolerance Test1

1954 • 47 citations

Stimulation of the synthesis of hepatic fatty acid synthesizing enzymes of hypophysectomized rats by 3,5,3′-l-triiodothyronine

1977 • 46 citations

Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis

1979 • 45 citations

Effects of Insulin on Glucose Metabolism and Glucose Transport in Fat Cells of Hormone-Treated Hypophysectomized Rats: Evidence That Growth Hormone Restricts Glucose Transport*

1979 • 43 citations

Effects of epinephrine on glucose transport and metabolism in adipose tissue of normal and hypothyroid rats

1968 • 43 citations

Levels of rat glucose-6-phosphate dehydrogenase messenger RNA.

1978 • 43 citations

Dose-response studies on the inhibitory effect of thyroid hormones on insulin secretion in the rat

1978 • 41 citations

Thyroxine treatment and insulin secretion in the rat

1975 • 41 citations

Influence of thyroid state on the effects of glycerol on gluconeogenesis and energy metabolism in perfused rat liver

1977 • 39 citations

Changes in hepatic fatty acid synthesis following glucagon injections in vivo

1973 • 39 citations

Dietary regulation of 6-phosphogluconate dehydrogenase synthesis.

1976 • 37 citations

Carbohydrate Metabolism in Thyrotoxicosis: Studies on Insulin Secretion before and after Remission from the Hyperthyroid State

1978 • 36 citations

Adaptive synthesis of fatty acid synthetase and acetyl-CoA carboxylase by isolated rat liver cells

1975 • 35 citations

Diet-Dependence of Rat Liver Glucose 6-Phosphate Dehydrogenase Levels

1968 • 34 citations

Age-Related Reduction in Response of Hepatic Enzymes to 3,5,3'-Triiodothyronine Administration*

1979 • 34 citations

Thyroid Hormone-Carbohydrate Interaction in the Rat

1981 • 34 citations

Effects of hypo- and hyper-thyroidism on liver composition, blood glucose, ketone bodies and insulin in the male rat

1972 • 33 citations

EflFect of Hyperthyroidism on Insulin and Glucose Dynamics in Rabbits

1973 • 33 citations

THE DISTURBANCE OF CARBOHYDRATE METABOLISM IN HYPERTHYROIDISM

1940 • 33 citations

Effects of Hypothyroidism, Hyperthyroidism, and Thyroxine on Net Synthesis of Plasma Proteins by the Isolated Perfused Rat Liver

1973 • 33 citations

Regulation of malic enzyme synthesis by thyroid hormone and glucagon: Inhibitor and kinetic experiments

1978 • 30 citations

Translation of rat liver fatty acid synthetase mRNA in a cell-free system derived from wheat germ

1978 • 29 citations

The Thyroid and Diabetes

1946 • 28 citations

Studies on the Effect of Hyperthyroidism on the Insulin Response to Hyperglycemia in the Dog

1971 • 27 citations

Quantitation of messenger RNA levels for rat liver 6-phosphogluconate dehydrogenase.

1978 • 27 citations

In vivo glucose turnover in hypo- and hyperthyroid starved rat

1980 • 26 citations

Hormonal regulation of hepatic fatty acid synthetase in chick embryo. Role of insulin.

1978 • 25 citations

Effect of Thyroxine Administration on Enzymes Associated with Glucose Metabolism in the Liver.

1967 • 22 citations

Inhibition of malic enzyme induction by triiodothyronine in the diabetic rat: Reversal by fructose feeding

1980 • 20 citations

Futile hydrogen cycling in liver cells from triiodothyronine treated rats

1977 • 20 citations

The Action of the Thyroid on Diabetes

1948 • 20 citations

Effects of adrenergic stimulating and blocking agents on glucose-induced insulin responses in human thyrotoxicosis

1978 • 18 citations

Thyroid hormones and lipogenesis from glucose in rat fat cells

1977 • 16 citations

Development of Ketonemia in Fasting Patients with Hyperthyroidism

1979 • 16 citations

Thyroid Hormones Influence Starvation-Induced Hepatic Protein Loss in the Rat: Possible Role of Thyroid Hormones in the Generation of Labile Protein*

1980 • 15 citations

Studies on the Effect of Thyroxine Replacement Therapy on the Increased Insulin Response to Hyperglycemia in the Thyroidectomized Dog

2009 • 15 citations

The inhibition of insulin secretion from the perfused rat pancreas after thyroxine treatment

1976 • 14 citations

Effects of Thyroidectomy and Thyroxine on Plasma Growth Hormone and Insulin Levels in Rats

1977 • 14 citations

Hormonal control of the glycerol-1-phosphate system by thyroid hormones

1966 • 13 citations

The Effects of Growth Hormone Treatment of Thyroid-Deficient Pregnant Rats on Maternal and Fetal Carbohydrate Metabolism

1976 • 13 citations

The influence of diet on the lipogenic response to thyroxine in rat liver

1975 • 12 citations

Regulation of Glucose-6-phosphate Dehydrogenase and 6-Phosphogluconate Dehydrogenase in the Meal-fed Rat

1975 • 12 citations

Metabolic interaction of ethanol and sorbitol in relation to redox state of liver cytosol in hypo-, hyper-, and euthyroid rats

1971 • 11 citations

Interaction of T3 and carbohydrate in the induction of lipogenic enzymes

1981 • 10 citations

Influence of Thyroid Hormone on Glycogen Metabolism in Rat Liver

1975 • 10 citations

Effect of acute administration of triiodothyronine in chicken. Liver glycogen depletion and amino acid incorporation to proteins

1978 • 9 citations

Effect of Thyroxine on the Hepatic Glycogen and Glucose-6-Phosphatase Activity of Developing Rats

1980 • 8 citations

Metabolic Response to Short Periods of Starvation in Hypo- and Hyper-Thyroid Male Rats

1978 • 7 citations

Effects of glucose, insulin and adrenalin on glycerol metabolism in adipose tissue from hypothyroid rats

1978 • 7 citations

The Effects of Thyroid State on Rat Liver Hexokinase Isozymes

1972 • 7 citations

Cyclic AMP and lipogenesis in fat cells from thyroidectomized rats

1979 • 7 citations

The Glycosuria of Hyperthyroidism and Its Clinical Significance

1931 • 6 citations

Actions of Aminophylline on the Blood Sugar, Serum Insulin and Serum free Fatty Acid Responses to Glucose in Hyperthyroid Dogs

1979 • 6 citations

Effacts of L-Triiodothyronine on Insulin Secretion in Man

1973 • 3 citations

Effects of Thyroxine, Growth Hormone, and Pituitary Homogenates on Insulin Secretion and Glucose Uptake in Thyroidectomized Rats

1974 • 2 citations

Cited By (0)

Loading...