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Modulation of ATP Sensitive K+ Channels: A Novel Strategy to Reduce the Deleterious Effects of Anoxia

Data up to Jan 2025

Published1990
Citations17
References30

Total Citations Per Year

Abstract

References (30)

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Delayed neuronal death in the gerbil hippocampus following ischemia

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ATP-regulated K+ channels in cardiac muscle

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Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

The density and distribution of ischemic brain injury in the rat following 2?10 min of forebrain ischemia

1984 • 968 citations

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Distribution of galaninlike immunoreactivity in the rat central nervous system

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THE SULPHONYLUREA RECEPTOR MAY BE AN ATP-SENSITIVE POTASSIUM CHANNEL

1985 • 507 citations

The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells.

1987 • 452 citations

Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependence and comparison with cell-attached patches

1984 • 333 citations

Effects of hypoxia on rat hippocampal neurones in vitro.

1987 • 312 citations

Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones

1988 • 270 citations

Anoxia increases potassium conductance in hippocampal nerve cells

1982 • 262 citations

Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal slice

1982 • 261 citations

Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices

1989 • 237 citations

ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone.

1988 • 193 citations

Regulation of ATP-sensitive K+ channels in insulinoma cells: activation by somatostatin and protein kinase C and the role of cAMP.

1989 • 163 citations

Long‐lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid.

1988 • 162 citations

Anoxia produces smaller changes in synaptic transmission, membrane potential, and input resistance in immature rat hippocampus

1989 • 138 citations

Galanin and Glibenclamide Modulate the Anoxic Release of Glutamate in Rat CA3 Hippocampal Neurons

1990 • 115 citations

Activators of ATP-sensitive K+ channels reduce anoxic depolarization in CA3 hippocampal neurons

1990 • 108 citations

Nucleotides such as ATP may control the activity of ion channels

1987 • 75 citations

Galanin protects hippocampal neurons from the functional effects of anoxia

1989 • 51 citations

Mechanism of action of galanin on myenteric neurons

1988 • 50 citations

Galanin‐induced hyperpolarization and decreased membrane excitability of neurones in mudpuppy cardiac ganglia.

1989 • 46 citations

Anoxia on slow inward currents of immature hippocampal neurons

1989 • 36 citations

Anoxia reversibly suppresses neuronal calcium currents in rat hippocampal slices

1987 • 30 citations

Brief anoxic episodes induce long-lasting changes in synaptic properties of rat CA3 hippocampal neurons

1988 • 26 citations

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