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The comparative pharmacology of some psychotropic drugs.

Data up to Jan 2025

Published1959
Citations27
References176

Total Citations Per Year

Abstract

References (176)

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

1957 • 1,523 citations

3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists

1957 • 1,233 citations

The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs

1954 • 1,014 citations

Physiology and pharmacology of vomiting.

1953 • 684 citations

On the Presence of 3-Hydroxytyramine in Brain

1958 • 632 citations

A 24-HOUR PERIODICITY IN THE “LH-RELEASE APPARATUS” OF FEMALE RATS, DISCLOSED BY BARBITURATE SEDATION1

1950 • 537 citations

Injections of drugs into the lateral ventricle of the cat

1954 • 514 citations

DEPRESSION BY RESERPINE OF THE NORADRENALINE CONCENTRATION IN THE HYPOTHALAMUS OF THE CAT

1956 • 424 citations

Amine oxidase and amine metabolism.

1952 • 355 citations

Serotonin Release as a Possible Mechanism of Reserpine Action

1955 • 336 citations

In vivo Inhibition of Liver and Brain Monoamine Oxidase by 1-Isonicotinyl-2-Isopropyl Hydrazine.

1952 • 252 citations

[Treatment of depressive states with an iminodibenzyl derivative (G 22355)].

1957 • 236 citations

Serotonin as a mediator of reserpine action in brain.

1956 • 230 citations

Evidence That Serotonin Has a Role in Brain Function

1955 • 210 citations

PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY

1955 • 202 citations

PHARMACOLOGY OF RAUWOLFIA ALKALOIDS, INCLUDING RESERPINE

1954 • 198 citations

A Facilitation Action of Reserpine on the Central Nervous System

1954 • 192 citations

AMINE OXIDASES

1955 • 183 citations

Noradrenaline in Artery Walls and its Dispersal by Reserpine

1958 • 171 citations

Effect of drugs and metabolic alterations on brain stem arousal mechanism.

1954 • 166 citations

The pharmacological properties of 2-methyl-2-n-propyl-1,3-propanediol dicarbamate (miltown), a new interneuronal blocking agent.

1954 • 149 citations

The pharmacology of Rauwolfia.

1956 • 144 citations

Assessment of Drug Effects on Emotional Behavior

1956 • 142 citations

Factor I and γ-Aminobutyric Acid

1956 • 132 citations

Relationship of Hallucinogens to Adrenergic Cerebral Neurohumors

1955 • 126 citations

[Pharmacodynamic properties of 3-chloro-10-(3-dimethylaminopropyl)-phenothiazine hydrochloride (R.P. 4560); experimental study of a new substance used in potentialized anesthesia and in artificial hibernation].

1953 • 114 citations

CHOLINERGIC AND ADRENERGIC COMPONENTS IN THE NEUROHUMORAL CONTROL OF THE RELEASE OF LH IN THE RABBIT

1949 • 111 citations

Modifications of the pharmacology of reserpine and serotonin by iproniazid.

1957 • 104 citations

Comparison of maximal seizures evoked by pentylenetetrazol (metrazol) and electroshock in mice, and their modification by anticonvulsants.

1953 • 104 citations

Alterations in somatic afferent transmission through the thalamus by central mechanisms and barbiturates.

1957 • 100 citations

BLOCKADE OF THE RELEASE OF PITUITARY OVULATING HORMONE IN THE RAT BY CHLORPROMAZINE AND RESERPINE: POSSIBLE MECHANISMS OF ACTION1

1957 • 98 citations

Hydrazine derivatives of isonicotinic acid (rimifon marsilid) in the treatment of active progressive caseous-pneumonic tuberculosis; a preliminary report.

1952 • 97 citations

Reserpine Antagonism of Morphine Analgesia in Mice

1954 • 96 citations

THE METABOLISM OF EPINEPHRINE CONTAINING ISOTOPIC CARBON. III

1953 • 92 citations

A COMPARISON OF EFFECTS OF RESERPINE AND SOME BARBITURATES ON THE ELECTRICAL ACTIVITY OF CORTICAL AND SUBCORTICAL STRUCTURES OF THE BRAIN OF RABBITS

1955 • 89 citations

Self-Stimulation of the Brain Used as a Screening Method for Tranquilizing Drugs

1956 • 88 citations

Differential action of anesthetics and interneuron depressants upon EEG arousal and recruitment responses.

1956 • 86 citations

Effects of scopolamine and atropine electroencephalographic and behavioral reactions due to hypothalamic stimulation.

1956 • 84 citations

THE PHARMACOLOGICAL PROPERTIES OF α: β DIHYDROXY‐γ‐(2‐METHYLPHENOXY)‐PROPANE (MYANESIN)

1946 • 83 citations

Release of 5-Hydroxytryptamine by Benzoquinolizine Derivatives with Sedative Action

1957 • 83 citations

Potentiating Action of Chlorpromazine and Reserpine

1955 • 80 citations

Patterns of Tolerance to Lysergic Acid Diethylamide and Mescaline in Rats

1958 • 76 citations

SOME CENTRAL ACTIONS OF 5‐HYDROXYTRYPTAMINE AND VARIOUS ANTAGONISTS

1956 • 75 citations

Persistence of reserpine action after the disappearance of drug from brain: effect on serotonin.

1956 • 74 citations

On the mechanism of drug potentiation by iproniazid (2-isopropyl-1-isonicotinyl hydrazine).

1956 • 73 citations

COMPARISON OF SOME PHARMACOLOGICAL PROPERTIES OF CHLORPROMAZINE, PROMETHAZINE, AND PETHIDINE

1954 • 73 citations

Pharmacodynamic basis for the use of chlorpromazine in psychiatry.

1956 • 72 citations

SIGNIFICANCE OF SELECTED CENTRAL MECHANISMS FOR THE ANALYSIS OF THE ACTION OF RESERPINE

1955 • 71 citations

Effects of chlorpromazine on the central nervous system of the cat: a possible neural basis for action.

1956 • 67 citations

Effect of iproniazid on serotonin metabolism in vivo.

1957 • 65 citations

The effect of beta-diethylaminoethyl-diphenylpropylacetate hydrochloride (SKF No. 525-A) on hexobarbital.

1954 • 64 citations

Pharmacology of Lysergic Acid Diethylamide and Some of Its Related CompoundS

1957 • 64 citations

Some Indications of Cerebral Humoral Mechanisms

1953 • 63 citations

The Effect of Benzilic Acid Diethylaminoethylester, HCl (Benactyzine*) on Stress‐Induced Behaviour in the Rat.

1955 • 62 citations

The action of anticonvulsant drugs tested by electrical stimulation of the cortex, diencephalon and rhinencephalon in the unanesthetized rabbit

1957 • 58 citations

CHLORPROMAZINE AND NARCOTICS IN THE MANAGEMENT OF PAIN OF MALIGNANT LESIONS

1954 • 58 citations

Action of nicotine and of the "ganglioplegiques centraux" on the electrical activity of the brain.

1954 • 58 citations

A pharmacological analysis of the functional relationship between the brain stem arousal and diffuse thalamic projection systems.

1955 • 57 citations

A COMPARATIVE STUDY OF THE EFFECTS OF DRUGS ON THE AROUSAL SYSTEM OF THE BRAIN

1959 • 56 citations

Positive Reinforcement Produced by Stimulating Hypothalamus with Iproniazid and Other Compounds

1958 • 56 citations

A New Hallucinogen: 3,4,5-Trimethoxyphenyl-β-Aminopropane

1955 • 54 citations

EFFECTS OF MEPROBAMATE ON IMPRINTING IN WATERFOWL

1957 • 53 citations

New Blocking Agent against the Development of LSD-25 Psychosis

1955 • 52 citations

NEUROPHARMACOLOGICAL ASPECTS OF RESERPINE

1955 • 51 citations

MECHANISM OF BLOCKADE OF PITUITARY ACTIVATION IN THE RAT BY MORPHINE, ATROPINE AND BARBITURATES1

1955 • 50 citations

Effect of 2-methyl, 2-n-propyl-1,3-propanediol dicarbamate (Miltown) on Central Nervous System

1954 • 49 citations

Pharmacologic and toxicologic observations on hydrazine derivatives of isonicotinic acid (rimifon, marsilid).

1952 • 48 citations

Effect of Tranquilizing Drugs on Fighting Response of Siamese Fighting Fish

1956 • 46 citations

BIOLOGICAL ASSESSMENT OF TRANQUILLISERS. PART I

1958 • 45 citations

Experimental Induction of Conflict‐Behaviour in Cats: The Effect of some Anticholinergic Compounds.

1955 • 45 citations

[On the pharmacology of tofranil (N-(3-dimethylaminopropyl)-iminodibenzyl hydrochloride].

1959 • 45 citations

A neuropharmacological study on the effect of myanesin (tolserol) on motor systems.

1949 • 45 citations

The anti-emetic activity of 10-(gamma-dimethylaminopropyl)-2-chlorophenothiazine (chlorpromazine) in dog and cat.

1954 • 44 citations

Characterization of central effects of serpasil (reserpin, a new alkaloid of Rauwolfia serpentina B.) and of their antagonistic reactions.

1954 • 41 citations

Further Characterization of Central Effects of Reserpine (Serpasil)

1955 • 40 citations

Frenquel Corrects Certain Cerebral Electrographic Changes

1955 • 39 citations

Action of a Series of Benactyzine‐Derivatives*) and Other Compounds on Stress‐Induced Behaviour in the Rat.

1955 • 37 citations

The action of mephenesin and other interneuron depressants on the brain stem.

1954 • 37 citations

A New Group of Psychotomimetic Agents.

1958 • 36 citations

THE DEPRESSION OF PHOSPHOLIPID TURNOVER IN BRAIN TISSUE BY CHLORPROMAZTNE

1956 • 36 citations

Experimental Induction of Conflict‐Behaviour in Cats: Its Use in Pharmacological Investigations.

1955 • 34 citations

Tranquillizing Drugs and Morphine-mania in Cats

1957 • 32 citations

THE MODE OF ACTION OF MYANESIN

1947 • 31 citations

ESTIMATED DURATION OF THE SPONTANEOUS ACTIVATION WHICH CAUSES RELEASE OF OVULATING HORMONE FROM THE RAT HYPOPHYSIS1

1953 • 30 citations

Potentiating Effect of Iproniazid on Action of Some Sympathicomimetic Amines.

1954 • 30 citations

Effect of Drugs on Emotional Behaviour in Rats

1958 • 29 citations

Effects of various phenothiazines on minimal electroshock seizure threshold and spontaneous motor activity of mice.

1958 • 29 citations

INHIBITION OF HYPOTHALAMIC, MEDULLARY AND REFLEX VASOMOTOR RESPONSES BY CHLORPROMAZINE

1954 • 29 citations

An Interpretation of the Action of Psychotropic Drugs

1958 • 28 citations

The effect of reserpine and chlorpromazine on the response of the rat to acute stress.

1958 • 27 citations

THE ACTION OF CHLORPROMAZINE ON DIENCEPHALIC SYMPATHETIC ACTIVITY AND ON THE RELEASE OF ADRENOCORTICOTROPHIC HORMONE

1954 • 27 citations

Pharmacologic studies on a new central stimulant, alpha-(2-piperidyl) benzhydrol hydrochloride (MRD-108).

1954 • 26 citations

Cerebral Synaptic Inhibition by Serotonin and Iproniazid

1957 • 26 citations

INJECTIONS OF BULBOCAPNINE INTO THE CEREBRAL VENTRICLES OF CATS

1955 • 25 citations

Antagonism Studies on Reserpine and Certain GNS Depressants

1954 • 25 citations

A test for tranquillizing drugs.

1958 • 24 citations

Modification of the Menstrual Cycle in Rhesus Monkeys by Reserpine

1956 • 24 citations

The Effect of Benaetyzine on the Conditioned Responses in the Rat.

1956 • 23 citations

Effects of reserpine on conditioned avoidance behavior in normal and brain-operated monkeys.

1956 • 23 citations

Toxicity and effects of increasing doses of mescaline.

1957 • 23 citations

Studies on behavior. III. Effects of scopolamine on reversal of a discriminatory performance in pigeons.

1957 • 22 citations

The anticonvulsant activity of carbamate esters of certain 2,2-disubstituted-1,3-propanediols.

1952 • 22 citations

Central depressant effects of methyprylon.

1956 • 21 citations

The Effects of Reserpine and Chlorpromazine on Orienting Behavior and Retention of Conditioned Reflexes

1956 • 21 citations

The Potentiating Effect of Benactyzine Derivatives*) and some Other Compounds on Evipal Anaesthesia in Mice.

1956 • 21 citations

Chlorpromazine. I. The action of chlorpromazine and related phenothiazines on the EEG and its activation.

1958 • 21 citations

[Modifications of the electrocardiogram of rabbits by di-ethylamide of d-lysergic acid].

1952 • 20 citations

Pharmacology of the Psychotherapeutic Drug Benactyzine ( -Diethyl-aminoethyl Benzilate Hydrochloride)

1956 • 19 citations

Topische Bestimmung des zerebralen Angriffs von Reserpin (Serpasil)

1955 • 19 citations

Mode of Action of Phenaglycodol, A New Neurosedative Agent

1956 • 19 citations

Inhibitory actions of chlorpormazine on motor activity.

1955 • 18 citations

EFFECT OF RESERPINE ON VASOCONSTRICTION CAUSED BY SYMPATHOMIMETIC AMINES

1958 • 17 citations

Drugs preventing motion sickness at sea.

1954 • 17 citations

Reserpine (Serpasil) Effects on Epileptic Monkeys.

1955 • 16 citations

A new group of potent sedatives.

1953 • 16 citations

Effects of some tranquilizing and depressant drugs on conditioned avoidance behavior in monkeys.

1957 • 16 citations

A Note on an Indwelling Cannula for Intraventricular Injection of Drugs in the Unanesthetized Dog

1956 • 15 citations

The activity of some central depressant drugs in acute decorticate and diencephalic preparations.

1954 • 15 citations

Convulsions and Bizarre Behavior in Monkeys Receiving Chlorpromazine

1957 • 15 citations

Effect of Reserpine on Prolactin Content of Rabbit Pituitary.

1958 • 15 citations

Effects of Mescaline in Laboratory Animals and Influence of Ataraxics on Mescaline-Response

1956 • 15 citations

Differentiation between the Sedative Actions of 5‐Hydroxytryptamine and Reserpine in Mice by Means of two Stimulating Substances.

1958 • 15 citations

The effect of LSD-25 upon the cerebral blood flow and EEG in cats

1956 • 15 citations

BIOLOGICAL ASSESSMENT OF TRANQUILLISERS. PART II

1958 • 14 citations

The pharmacology of beta-dimethylaminoethyl-2-methylbenzhydrylether hydrochloride (BS 5930).

1956 • 14 citations

Occurrence of the “Waltzing Syndrome” in Mice after Administration of Aminodipropionitrile.

1957 • 14 citations

THE EFFECT OF MESCALINE ON DIFFERENTIATED CONDITIONAL REFLEXES

1956 • 14 citations

Pharmacological Properties of Recanescine, A New Sedative Alkaloid from Rauwolfia canescens Linn

1955 • 14 citations

PROPHYLACTIC AND THERAPEUTIC CONTROL OF VESTIBULAR DISTURBANCES WITH DIMENHYDRINATE

1951 • 14 citations

THERAPEUTIC PROCESS IN ELECTROSHOCK AND THE NEWER DRUG THERAPIES

1956 • 14 citations

Disturbed Chronic Psychotic Patients: Pilot Trial of "Stelazine"

1958 • 13 citations

Influence of chlorpromazine, reserpine, dibenzyline and desoxycorticosterone upon morphine-induced feline mania.

1956 • 13 citations

The pharmacologic activity of alpha-(4-piperidyl)-benzhydrol hydrochloride (azacyclonol hydrochloride); an ataractive agent.

1956 • 12 citations

A study of the neuropharmacologic properties of certain convulsants, anticonvulsants and reserpine.

1956 • 12 citations

The difference in action on normal and convulsive cortical activity between a local anaesthetic (lidocaine) and barbiturates.

1956 • 12 citations

The antiparkinson activity of benactyzine.

1957 • 11 citations

The central depressant profile of some substituted methathiazanones.

1958 • 11 citations

Pharmacological properties of benzazoles. II. Sites of action in the central nervous system.

1953 • 11 citations

[Activity of a new phenothiazine in psychiatry and neurology; therapeutic properties of 10-(3-dimethylamino-2-methyl-propyl)-3-methoxyphenothiazine].

1956 • 11 citations

[Chemical structure & pharmacological effects of the thiaxanthene analogs of chlorpromazine, promazine & mepazine].

1958 • 11 citations

The antiemetic activity of alkaloids of Rauwolfia serpentina.

1956 • 11 citations

The effect of alpha,beta-dihydrosy-gamma-(2 methylphenoxy) propane (myanesin, tolserol) on experimental spasticity in cats.

1949 • 11 citations

Electroencephalographic changes in the rat with mescaline intoxication.

1958 • 10 citations

Inhibitory Effect of Benactyzine*) Derivatives and Other Compounds on the Straub‐Herrmann Mouse Tail Reaction Due to Morphine.

1957 • 10 citations

Motion sickness.

1955 • 9 citations

Comparative effects of various Rauwolfia alkaloids on centrally evoked vasopressor responses.

1957 • 8 citations

The Effect of Benactyzine on the Electroencephalogram in Man.

1957 • 8 citations

A STEREOTYPED RESPONSE INDUCED BY MESCALINE IN MICE AS A MEANS OF INVESTIGATING THE PROPERTIES OF DRUGS ACTING ON THE CNS

1958 • 8 citations

Central depressant and anticonvulsant activity of compounds isomeric with 2-methyl-2-n-propyl-1, 3-propanediol dicarbamate (miltown).

1956 • 8 citations

A study of the anticonvulsant properties of phenobarbital and dilantin.

1954 • 8 citations

A method for the biological assay of reserpine and reserpine-like activity.

1957 • 8 citations

[Pharmcological study on hydroxyzine, U.C.B. 492; a disubstituted piperazine derivative].

1957 • 7 citations

On the evaluation of the anticonvulsive effect of different local anaesthetics.

1956 • 7 citations

On the Effect of Iproniazid on the Histamine Sensitivity of the Unanaesthetized Guinea‐pig.

1957 • 7 citations

A PSYCHOSIS CAUSED BY BENACTYZIN INTOXICATION

1958 • 7 citations

Phenaglycodol A New Antiepileptic Agent

1957 • 7 citations

[Hibernation & tranquilizing agents in psychiatric therapy].

1957 • 7 citations

The influence of ritalin (methylphenidate) on the behavioral and circulatory effects of reserpine.

1957 • 7 citations

Effects of Reserpine and Chlorpromazine on Nest Building and Thermal Preference in Rats

1955 • 6 citations

Pharmacologic Characterization of Reserpine Responses in Rats Pre-Treated with Iproniazid.

1958 • 6 citations

Pharmacological studies with deserpidine, a new alkaloid from Rauwolfia canescens.

1955 • 6 citations

The action of mephenesin upon three monosynaptic pathways of the cat.

1956 • 6 citations

[Some pharmacological investigations of mice with congenital rotatory disease].

1952 • 5 citations

Effects of Atropine on “Waltzing Syndrome” in Mice after Iminodipropionitrile

1958 • 4 citations

EEG-Befunde bei Pseudoschmerzreflexen

1956 • 4 citations

A Confirmatory Test for Mephenesin-Like Action of a Compound on Mice

1958 • 4 citations

THE INFLUENCE OF PACATAL ON THE CORTICOTROPHIN-RELEASING ACTIVITY OF THE HYPOPHYSIS

1958 • 4 citations

[Pharmacology of the ascending reticular system].

1957 • 3 citations

[Comparative action of products, numbers 3277 R.P., 4560 R.P., 4909 R.P. and of phenobarbital on convulsions induced by strychnine, picrotoxin, cocaine, cafeine and amphetamine].

1956 • 3 citations

[Motor control with special reference to tonus & spasticity].

1957 • 2 citations

Action of some phenothiazine derivatives on the effects of convulsant agents

1955 • 2 citations

[Therapeutic trials using a new phenothiazine derivative: levomepromazine (RP 7044)].

1957 • 2 citations

Adrenergic Block by Reserpine in Man.

1957 • 2 citations

[Effect of injection into the cerebral ventricles in dog of 3-chloro-10-(3-dimethylaminopropyl)-phenothiazine hydrochloride; central action].

1952 • 2 citations

[Influence of certain ganglioplegics and neuroplegics on the anticonvulsant effect of diphenylhydantion].

1955 • 1 citations

[Effects of serotonin (5-hydroxytryptamine) on a conditioned escape response in rats].

1957 • 1 citations

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