Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Genomic sequencing.

1984 • 8,343 citations

Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

1982 • 2,259 citations

Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture

1977 • 1,054 citations

Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture

1978 • 596 citations

Purification and Partial Amino Acid Sequence of Osteogenin, a Protein Initiating Bone Differentiation

1989 • 405 citations

L‐ascorbic acid 2‐phosphate stimulates collagen accumulation, cell proliferation, and formation of a three‐dimensional tissuelike substance by skin fibroblasts

1989 • 374 citations

Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth.

1987 • 347 citations

Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography.

1987 • 334 citations

Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors.

1988 • 261 citations

TGF-β1 Prevents Hypertrophy of Epiphyseal Chondrocytes: Regulation of Gene Expression for Cartilage Matrix Proteins and Metalloproteases

1993 • 240 citations

ISOLATION AND PROPERTIES OF THE ANTERIOR HYPOPHYSEAL GROWTH HORMONE

1945 • 205 citations

Induction of proliferation or hypertrophy of chondrocytes in serum-free culture: the role of insulin-like growth factor-I, insulin, or thyroxine.

1992 • 166 citations

Matrix-Induced Endochondral Bone Differentiation: Influence of Hypophysectomy, Growth Hormone, and Thyroid-Stimulating Hormone

1980 • 138 citations

β1 Integrins Mediate Chondrocyte Interaction with Type I Collagen, Type II Collagen, and Fibronectin

1993 • 124 citations

Review of Slipped Capital Femoral Epiphysis Associated with Endocrine Disease

1993 • 113 citations

Thyroid hormone, insulin, and glucocorticoids are sufficient to support chondrocyte differentiation to hypertrophy: a serum-free analysis.

1992 • 108 citations

Isolation and characterization of a cDNA clone for the amino-terminal portion of the pro-alpha 1(II) chain of cartilage collagen.

1984 • 104 citations

Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10

1992 • 93 citations

Modulation of the rabbit chondrocyte phenotype by retinoic acid terminates type II collagen synthesis without inducing type I collagen: The modulated phenotype differs from that produced by subculture

1986 • 90 citations

GROWTH AND DIFFERENTIATION OF THE SKELETON IN THYROIDECTOMIZED-HYPOPHYSECTOMIZED RATS TREATED WITH THYROXIN, GROWTH HORMONE, AND THE COMBINATION

1954 • 62 citations

Development of a serum-free system to study the effect of growth hormone and insulinlike growth factor-I on cultured postembryonic growth plate chondrocytes

1992 • 51 citations

Modulation and Reexpression of the Chondrocyte Phenotype; Mediation by Cell Shape and Microfilament Modification

1988 • 49 citations

Quantitative analysis of type X-collagen biosynthesis by embryonic-chick sternal cartilage

1986 • 30 citations