Determinants of efficacy of immunotherapy with tumor-derived heat shock protein gp96.

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway

2000 • 1,299 citations

A Mechanism for the Specific Immunogenicity of Heat Shock Protein-Chaperoned Peptides

1995 • 838 citations

Immunotherapy of Tumors with Autologous Tumor-Derived Heat Shock Protein Preparations

1997 • 699 citations

Heat shock protein 70-associated peptides elicit specific cancer immunity.

1993 • 631 citations

Heat Shock Protein–Peptide Complexes, Reconstituted In Vitro, Elicit Peptide-specific Cytotoxic T Lymphocyte Response and Tumor Immunity

1997 • 567 citations

Heat Shock Proteins Come of Age: Primitive Functions Acquire New Roles in an Adaptive World

1998 • 560 citations

Tumor rejection antigens of chemically induced sarcomas of inbred mice.

1986 • 463 citations

Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways

1999 • 413 citations

Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70.

1994 • 411 citations

Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: A pilot study

2000 • 250 citations

Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

1984 • 249 citations

Cutting Edge: Heat Shock Protein gp96 Induces Maturation and Migration of CD11c+ Cells In Vivo

2000 • 223 citations

Immunization with a Lymphocytic Choriomeningitis Virus Peptide Mixed with Heat Shock Protein 70 Results in Protective Antiviral Immunity and Specific Cytotoxic T Lymphocytes

1998 • 193 citations

Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells.

2001 • 173 citations

Heat Shock Protein Vaccines Against Cancer

1993 • 156 citations

Immunotherapy of human cancer: lessons from mice

2000 • 143 citations

The Dual Nature of Specific Immunological Activity of Tumor-derived gp96 Preparations

1999 • 137 citations

Purification of Heat Shock Protein–Peptide Complexes for Use in Vaccination against Cancers and Intracellular Pathogens

1997 • 107 citations

The serologically unique cell surface antigen of zajdela ascitic hepatoma is also its tumor‐associated transplantation antigen

1984 • 102 citations

Heat-shock protein-based anticancer immunotherapy: an idea whose time has come.

1998 • 70 citations

Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70

2001 • 65 citations

Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.

1999 • 64 citations

The immunoprotective MHC II epitope of a chemically induced tumor harbors a unique mutation in a ribosomal protein

2001 • 40 citations