Microtubules and Beta Cell Secretion

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1967 • 2,783 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

Electron microscope studies on the structure of natural and synthetic protein filaments from striated muscle

1963 • 1,452 citations

THE MECHANISM OF ACTION OF COLCHICINE

1967 • 1,049 citations

FORMATION OF ARROWHEAD COMPLEXES WITH HEAVY MEROMYOSIN IN A VARIETY OF CELL TYPES

1969 • 963 citations

Effects of Cytochalasins on Mammalian Cells

1967 • 947 citations

ULTRASTRUCTURE AND FUNCTION OF GROWTH CONES AND AXONS OF CULTURED NERVE CELLS

1971 • 769 citations

Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro

1964 • 540 citations

New Hypothesis of Insulin Secretion

1968 • 539 citations

PROMOTION OF INSULIN SECRETION BY GLUCAGON

1965 • 501 citations

MICROFILAMENTS AND CELL LOCOMOTION

1971 • 437 citations

Cation Requirements for Insulin Secretion in the Isolated Perfused Pancreas

1966 • 386 citations

Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion

1972 • 360 citations

Isolation and culture of the islets of Langerhans of the guinea pig

1965 • 348 citations

Perifusion of Isolated Rat Islets in Vitro: Participation of the Microtubular System in the Biphasic Release of Insulin

1972 • 311 citations

The role of calcium and magnesium in insulin secretion from rabbit pancreas studied in vitro

1967 • 308 citations

Electrical Activity in Pancreatic Islet Cells

1968 • 301 citations

Stimulus-Secretion Coupling of Glucose-Induced Insulin Release. III. Uptake of⁴⁵Calcium by Isolated Islets of Langerhans1

1971 • 287 citations

An adrenergic receptor mechanism for the control of cyclic 3′5′ adenosine monophosphate synthesis in tissues

1967 • 285 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL STUDIES ON HELA CELL CULTURES EXPOSED TO SPINDLE INHIBITORS WITH SPECIAL REFERENCE TO THE INTERPHASE CELL

1964 • 256 citations

Cytokinesis: Filaments in the cleavage furrow

1968 • 242 citations

Principles of Biomolecular Organization.

1967 • 238 citations

Cytochalasin A and B

1972 • 211 citations

The Stimulus-Secretion Coupling of Glucose-Induced Insulin Release. VII. A PROPOSED SITE OF ACTION FOR ADENOSINE-3′,5′-CYCLIC MONOPHOSPHATE

1972 • 209 citations

Inhibition of the Transport of Several Hexoses in Mammalian Cells by Cytochalasin B

1972 • 209 citations

Cytoplasmic microtubules in mammalian cells

1964 • 209 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Vinblastine-Induced Precipitation of Microtubule Protein

1969 • 205 citations

DERMATITIS CAUSED BY PENICILLIN IN MILK

1958 • 202 citations

Beta Adrenergic Stimulation of Insulin Release in Man

1967 • 195 citations

Microtubule Crystals: A New Biophysical Phenomenon induced by Vinca Alkaloids

1968 • 183 citations

Electron microscopy of the beta cell of the pancreas

1961 • 182 citations

Cytochalasin B: Effects on Cell Morphology, Cell Adhesion, and Mucopolysaccharide Synthesis

1972 • 180 citations

Observations on the substructure of flagellar fibres

1966 • 178 citations

An analysis of salivary gland morphogenesis: Role of cytoplasmic microfilaments and microtubules

1972 • 174 citations

Ultrastructural Changes in Islets of the Rat Produced by Tolbutamide

1961 • 174 citations

Cytochalasin B: Inhibition of D-2-Deoxyglucose Transport into Leukocytes and Fibroblasts

1972 • 166 citations

ENDOCYTOSIS IN CHANG LIVER CELLS

1971 • 165 citations

The Stimulus-secretion Coupling of Glucose-induced Insulin Release: V. The Participation of a Microtubular-microfilamentous System

1971 • 164 citations

Possible Role of Microtubules in Thyroid Secretion

1970 • 162 citations

A possible role of microtubules in catecholamine release from the adrenal medulla: effect of colchicine, vinca alkaloids and deuterium oxide.

1971 • 161 citations

Cytochalasin B, Its Interaction with Actin and Actomyosin from Muscle

1972 • 159 citations

Stimulation of Insulin Secretion by Theophylline

1967 • 157 citations

A New Method for the Measurementin Vitroof Pancreatic Insulin Secretion

1967 • 155 citations

Insulin Release After ACTH, Glucagon and Adenosine-3′-5′-Phosphate (Cyclic AMP) in the Perfused Isolated Rat Pancreas

1967 • 147 citations

ON THE ROLE OF MICROTUBULES IN MOVEMENT AND ALIGNMENT OF NUCLEI IN VIRUS-INDUCED SYNCYTIA

1968 • 146 citations

Histamine release from rat peritoneal mast cells: inhibition by colchicine and potentiation by deuterium oxide.

1968 • 140 citations

Effects of Cytochalasin B upon Microfilaments Involved in Morphogenesis of Salivary Epithelium

1970 • 136 citations

Inhibition of Release of Dopamine-β-Hydroxylase and Norepinephrine from Sympathetic Nerves by Colchicine, Vinblastine, or Cytochalasin-B

1972 • 132 citations

ON THE ACTION OF COLCHICINE

1965 • 131 citations

Cytochalasin B inhibits thyroid secretion

1971 • 130 citations

Role of Contractile Microfilaments in the Release of Histamine from Mast Cells

1972 • 129 citations

Human Polymorphonuclear Leukocytes: Demonstration of Microtubules and Effect of Colchicine

1967 • 129 citations

Antimitotic Substances

1968 • 123 citations

Effects of colchicine on axonal transport and ultrastructure of the hypothalamo-neurohypophyseal system of the rat

1971 • 122 citations

Cytochalasin B: Effects on Microfilaments and Movement of Melanin Granules within Melanocytes

1972 • 114 citations

THE STIMULUS-SECRETION COUPLING OF GLUCOSE-INDUCED INSULIN RELEASE

1971 • 100 citations

STIMULATION BY GLUCAGON OF INSULIN RELEASE FROM RABBIT PANCREAS IN VITRO

1966 • 93 citations

Glucoreceptor Mechanisms in Islets of Langerhans

1972 • 91 citations

Beta Cell Secretion—from the Standpoint of a Pathobiologist

1970 • 90 citations

Cytochalasin B. IV. Inhibition and stimulation of chemotaxis of rabbit and human polymorphonuclear leukocytes.

1972 • 89 citations

The fine structure and innervation of the beta and delta cells in the islet of Langerhans of the cat

1967 • 85 citations

Cytochalasin B: Effects upon Microfilaments Involved in Morphogenesis of Estrogen-Induced Glands of Oviduct

1970 • 84 citations

ENHANCEMENT BY CAFFEINE OF GLUCAGON-INDUCED AND TOLBUTAMIDE-INDUCED INSULIN RELEASE FROM ISOLATED FŒTAL PANCREATIC TISSUE

1967 • 83 citations

PURIFICATION OF INTACT MICROTUBULES FROM BRAIN

1970 • 81 citations

Structures Corresponding to Terminal Bars and Terminal Web in Many Types of Cells

1960 • 77 citations

ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS

1969 • 76 citations

The Stimulus-Secretion Coupling of Glucose-Induced Insulin Release: IX. The Participation of the Beta Cell Web

1972 • 69 citations

Involvement of the microtubule-microfilament system in thyroid secretion

1970 • 69 citations

ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS

1969 • 67 citations

Neural Tube Closure Defects caused by Cytochalasin ?

1972 • 56 citations

Electron Microscopy of the Rat Pancreas: Effects of Glucagon Administration

1959 • 54 citations

The Stimulus‐Secretion Coupling of Glucose‐Induced Insulin Release VIII. Combined Effects of Glucose and Sulfonylureas*

1972 • 54 citations

A Comparative electron microscopic study of cytoplasmic microtubules and axial unit tubules in a spermatozoon and a protozoan

1966 • 53 citations

Cytochalasin B

1972 • 52 citations

Ultramicroscopic Studies of Rabbit Pancreas during Cortisone Treatment

1963 • 50 citations

Studies on Insulin Secretionin Vitrofrom Isolated Islets of the Rat Pancreas

1968 • 50 citations

Actin-like Properties of Colchicine Binding Protein isolated from Brain

1970 • 46 citations

Similar structural bases for the storage and release of secretory material in adreno-medullary and ? pancreatic cells

1966 • 40 citations

Acid Phosphatase Activity in Secretory Granules of Pancreatic Beta Cells of Normal Rats

1971 • 34 citations

The Stimulus-Secretion Coupling of Glucose-Induced Insulin Release - VI. Analogy Between the Insulinotropic Mechanisms of Sugars and Amino Acids

1971 • 34 citations

[A possible role for calcium in the stimulus-secretion coupling for glucose-induced insulin secretion].

1970 • 29 citations

Formation of secretory granules in pancreatic islet B cells of cortisone-treated rabbits.

1968 • 29 citations

Cell division: Combined anti-mitotic effects of colchicine and heavy water on first cleavage in the eggs of Arbacia punctulata

1968 • 28 citations

Ultrastructure of ?-cells during the dynamic response to glucose and tolbutamide in vitro

1970 • 23 citations

Uptake of 45-calcium by isolated islets of Langerhans

1970 • 18 citations

Effect of glucose and epinephrine on 45calcium efflux from perifused islets

1972 • 4 citations