Differential sensitivity to isoprenaline of troponin I and phospholamban phosphorylation in isolated rat hearts

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Molecular weight analysis of oligopeptides by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate

1971 • 1,736 citations

Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1971 • 810 citations

Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine.

1980 • 568 citations

Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium-calmodulin-dependent phosphorylations

1979 • 454 citations

[A simple technic for extremely rapid freezing of large pieces of tissue].

1960 • 453 citations

The Stimulation of Calcium Transport in Cardiac Sarcoplasmic Reticulum by Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

1974 • 398 citations

beta-Adrenergic stimulation of phospholamban phosphorylation and Ca2+-ATPase activity in guinea pig ventricles.

1983 • 348 citations

Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake.

1984 • 255 citations

Adenosine 3':5'-monophosphate dependent protein kinase from bovine heart. Characterization of the catalytic subunit

1977 • 218 citations

Hormonal control of protein phosphorylation.

1977 • 213 citations

Complete complementary DNA-derived amino acid sequence of canine cardiac phospholamban.

1987 • 201 citations

Simultaneous isolation of adenosine 3′,5′-cyclic monophosphate (cAMP) and guanosine 3′,5′-cyclic monophosphate (cGMP) in small tissue samples

1974 • 198 citations

Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts

1988 • 196 citations

Studies on the phosphorylation of the inhibitory subunit of troponin during modification of contraction in perfused rat heart

1976 • 192 citations

Phosphorylation of the inhibitory subunit of troponin and its effect on the calcium dependence of cardiac myofibril adenosine triphosphatase

1976 • 188 citations

Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slices.

1978 • 178 citations

The role of glutathione status in the protection against ischaemic and reperfusion damage: Effects of N-acetyl cysteine

1988 • 178 citations

Isoproterenol-induced phosphorylation of a 15-kilodalton sarcolemmal protein in intact myocardium.

1985 • 159 citations

Correlation between contraction and phosphorylation of the inhibitory subunit of troponin in perfused rat heart

1975 • 151 citations

The phosphorylation of troponin I from cardiac muscle

1975 • 148 citations

Phospholamban forms Ca2+-selective channels in lipid bilayers.

1988 • 140 citations

A General Strategy for Parameter Estimation from Isosteric and Allosteric‐Kinetic Data and Binding Measurements

1972 • 128 citations

Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins.

1989 • 126 citations

Phosphorylation of phospholamban in intact myocardium. Role of Ca2+-calmodulin-dependent mechanisms.

1985 • 120 citations

Functional compartmentation of cyclic AMP and protein kinase in heart.

1981 • 118 citations

Calcium sensitivity of the contractile system and phosphorylation of troponin in hyperpermeable cardiac cells.

1980 • 112 citations

Transient state kinetic studies of Ca2+-dependent ATPase and calcium transport by cardiac sarcoplasmic reticulum. Effect of cyclic AMP-dependent protein kinase-catalyzed phosphorylation of phospholamban.

1980 • 110 citations

Control of calcium transport in the myocardium by the cyclic AMP-Protein kinase system.

1975 • 102 citations

Identification of an endogenous protein kinase C activity and its intrinsic 15-kilodalton substrate in purified canine cardiac sarcolemmal vesicles.

1985 • 95 citations

Mechanism of the stimulation of calcium ion dependent ATPase of cardiac sarcoplasmic reticulum by adenosine 3',5'-monophosphate dependent protein kinase

1980 • 86 citations

Characterization of the intrinsic cAMP-dependent protein kinase activity and endogenous substrates in highly purified cardiac sarcolemmal vesicles.

1982 • 83 citations

Effects of forskolin on contractile responses and protein phosphorylation in the isolated perfused rat heart

1987 • 62 citations

The site of phosphorylation of troponin I in the perfused rabbit heart. The effect of adrenaline

1980 • 57 citations

Dissociation between contraction and relaxation: The possible role of phospholamban phosphorylation

1987 • 33 citations

Protein phosphorylation: Quantitative analysis in vivo and in intact cell systems

1980 • 30 citations

Concerted phosphorylation of the 26-kilodalton phospholamban oligomer and of the low molecular weight phospholamban subunits

1986 • 25 citations

Heterogeneous distribution of calmodulin‐and cAMP‐dependent regulation of Ca²⁺ uptake in cardiac sarcoplasmic reticulum subfracitons

1988 • 16 citations

Dephosphorylation of myofibrillar proteins in actomyosin preparations and in isolated perfused rat hearts after β-agonist withdrawal

1982 • 8 citations