Interaction of distinct nuclear proteins with sequences controlling the expression of polyomavirus early genes.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

1984 • 443 citations

Specific interaction between enhancer-containing molecules and cellular components

1984 • 374 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

Negative regulation of viral enhancers in undifferentiated embryonic stem cells

1985 • 347 citations

Cell-type-specific contacts to immunoglobulin enhancers in nuclei

1985 • 341 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication

1981 • 304 citations

Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene

1985 • 291 citations

Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro

1985 • 289 citations

An exonuclease protection assay reveals heat-shock element and TATA box DNA-binding proteins in crude nuclear extracts

1985 • 280 citations

Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: Nature of the binding domain

1985 • 255 citations

Polyoma virus DNA replication requires an enhancer

1984 • 253 citations

Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression.

1985 • 206 citations

Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells

1981 • 199 citations

Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor.

1984 • 199 citations

A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

1985 • 196 citations

Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit.

1983 • 176 citations

Polyoma DNA sequences involved in control of viral gene expression in murine embryonal carcinoma cells

1981 • 146 citations

Expression of polyoma early functions in mouse embryonal carcinoma cells depends on sequence rearrangements in the beginning of the late region

1980 • 145 citations

Isolation and characterization of polyoma host range mutants that replicate in nullipotential embryonal carcinoma cells.

1981 • 144 citations

Duplications of a mutated simian virus 40 enhancer restore its activity

1985 • 141 citations

DNA fragments from F9 PyEC mutants increase expression of heterologous genes in transfected F9 cells

1983 • 134 citations

Polyomavirus origin for DNA replication comprises multiple genetic elements

1983 • 132 citations

Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors.

1985 • 127 citations

Specific interaction of cellular factors with the B enhancer of polyoma virus.

1985 • 124 citations

A viral enhancer element specifically active in human haematopoietic cells

1985 • 84 citations

Sequence specificity of exonuclease III fromE. coli

1982 • 80 citations

Specific protein-DNA interaction at four sites flanking the chicken lysozyme gene

1982 • 70 citations

Common features of polyomavirus mutants selected on PCC4 embryonal carcinoma cells.

1985 • 49 citations

Location of sequences in polyomavirus DNA that are required for early gene expression in vivo and in vitro.

1984 • 49 citations

Physical and biological features of polyoma virus mutants able to infect embryonal carcinoma cell lines

1982 • 48 citations

Functional analysis of the regulatory region of polyoma mutant F9-1 DNA

1985 • 34 citations

Enhancers as Transcriptional Control Elements

1984 • 1 citations