Ectopic Expression of Guanylyl Cyclase C in CD34⁺ Progenitor Cells in Peripheral Blood

Screening for Colorectal Cancer

1990 • 1,233 citations

Cancer statistics, 1990

1990 • 818 citations

Illegitimate transcription: transcription of any gene in any cell type.

1989 • 647 citations

An Evaluation of the Carcinoembryonic Antigen (CEA) Test for Monitoring Patients With Resected Colon Cancer

1993 • 432 citations

Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients.

1998 • 363 citations

Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction

1995 • 343 citations

Access to a Messenger RNA Sequence or Its Protein Product Is Not Limited by Tissue or Species Specificity

1989 • 306 citations

Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.

1997 • 290 citations

The National Cancer Data Base report on colon cancer

1996 • 252 citations

Activation of Intestinal Guanylate Cyclase by Heat-Stable Enterotoxin of Escherichia coli: Studies of Tissue Specificity, Potential Receptors, and Intermediates

1980 • 216 citations

Keratin gene expression in non-epithelial tissues. Detection with polymerase chain reaction.

1993 • 208 citations

Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues

1996 • 204 citations

Low specificity of cytokeratin 19 reverse transcriptase-polymerase chain reaction analyses for detection of hematogenous lung cancer dissemination.

1995 • 197 citations

Screening for Colorectal Cancer

1995 • 177 citations

The detection of breast carcinoma micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction

1995 • 166 citations

Molecular and immunological detection of circulating tumor cells and micrometastases from solid tumors

1996 • 163 citations

Local recurrence of colorectal cancer: Effect of early detection and aggressive surgery

1986 • 161 citations

Detection of micrometastasis by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes

1999 • 156 citations

Detection of cytokeratins 19/20 and guanylyl cyclase C in peripheral blood of colorectal cancer patients

1999 • 148 citations

Cost of Patient Follow-up After Potentially Curative Colorectal Cancer Treatment

1995 • 140 citations

Escherichia coli cytotoxins and enterotoxins

1992 • 138 citations

Use of CEA as an Indicator of Early Recurrence and as a Guide to a Selected Second-look Procedure in Patients with Colorectal Cancer

1978 • 130 citations

Does methodic long-term follow-up affect survival after curative resection of colorectal carcinoma?

1993 • 119 citations

Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line.

1988 • 115 citations

Guanylyl Cyclase C Messenger RNA Is a Biomarker for Recurrent Stage II Colorectal Cancer

1999 • 113 citations

Age-related differences in receptors for Escherichia coli heat-stable enterotoxin in the small and large intestine of children

1988 • 105 citations

Assessment of serial carcinoembryonic antigen (CEA) assays in postoperative detection of recurrent colorectal cancer

1976 • 100 citations

Hemopoiesis in healthy old people and centenarians: well-maintainedresponsiveness of CD34+ cells to hemopoietic growth factors and remodelingof cytokine network

2000 • 96 citations

Combined nested RT-PCR assay for prostate-specific antigen and prostate-specific membrane antigen in prostate cancer patients: correlation with pathological stage.

1998 • 91 citations

Colon cancer overview

1992 • 91 citations

Use of guanylyl cyclase c for detecting micrometastases in lymph nodes of patients with colon cancer

1998 • 86 citations

The localization of guanylate cyclase in rat small intestinal epithelium

1975 • 81 citations

Escherichia coli heat-stable toxin receptors in human colonic tumors

1994 • 79 citations

Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: implications for the detection of hematogenous prostate cells and standardization

1998 • 76 citations

Pluripotent and lineage-committed CD34+ subsets in leukapheresis products mobilized by G-CSF, GM-CSF vs. a combination of both.

1996 • 71 citations

Outcomes after detection of metastatic carcinoma of the colon and rectum in a national hospital system.

1996 • 68 citations

A prospective evaluation of serum carcinoembryonic antigen (CEA) levels in the management of colorectal carcinoma

1984 • 65 citations

CK20 gene expression: technical limits for the detection of circulating tumor cells.

1999 • 64 citations

Escherichia coli heat-stable enterotoxin receptors

1996 • 63 citations

T84 cell receptor binding and guanyl cyclase activation by Escherichia coli heat-stable toxin

1987 • 62 citations

Disease‐free survival and recurrence after resection of colorectal carcinoma

1981 • 58 citations

Binding ofE. coli heat-stable enterotoxin to rat intestinal brush borders and to basolateral membranes

1987 • 52 citations

Small and Large Intestinal Guanylate Cyclase Activity in Children: Effect of Age and Stimulation by Escherichia coli Heat-Stable Enterotoxin

1987 • 48 citations

Receptors forEscherichia coli heat stable enterotoxin in human intestine and in a human intestinal cell line (Caco-2)

1993 • 47 citations

Comparison of receptors for Escherichia coli heat-stable enterotoxin: novel receptor present in IEC-6 cells

1993 • 45 citations

Epithelial tumour cell detection and the unsolved problems of nested RT-PCR: a new sensitive one step method without false positive results

1998 • 43 citations

Heterogeneity of guanylyl cyclase C expressed by human colorectal cancer cell lines in vitro.

1998 • 43 citations

Ligand‐based histochemical localization and capture of cells expressing heat‐stable enterotoxin receptors

1993 • 40 citations

EPIDEMIOLOGY OF CANCER IN THE UNITED STATES

1992 • 38 citations

Ectopic (Illegitimate) Transcription: New Possibilities for the Analysis and Diagnosis of Human Genetic Disease

1994 • 37 citations

Minimal illegitimate levels of cytokeratin K19 expression in mononucleated blood cells detected by a reverse transcription PCR method (RT-PCR)

1997 • 36 citations

Colonoscopy After Curative Resection of Colorectal Cancer

1986 • 23 citations

Goals of screening

1992 • 21 citations

Postoperative evaluation of patients with colorectal cancer.

1995 • 16 citations

Distribution of membrane bound guanylyl cyclases in human intestine.

1994 • 15 citations

Illegitimate transcription: its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia

1998 • 13 citations