Carbohydrate and Oxidative Metabolism in Neural Systems

Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain

1964 • 2,227 citations

Brain Metabolism during Fasting*

1967 • 1,590 citations

Adenyl Cyclase

1962 • 853 citations

Regulation of Glucose Uptake in Muscle

1961 • 595 citations

The Relationships between Substrates and Enzymes of Glycolysis in Brain

1964 • 551 citations

The Measurement of Pyridine Nucleotides by Enzymatic Cycling

1961 • 490 citations

Multiple Hexokinases of Rat Tissues

1966 • 483 citations

THE ASSOCIATION OF HEXOKINASE WITH PARTICULATE FRACTIONS OF BRAIN AND OTHER TISSUE HOMOGENATES

1953 • 460 citations

THE REGIONAL AND SUBCELLULAR DISTRIBUTION OF 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE IN THE CENTRAL NERVOUS SYSTEM

1967 • 458 citations

Facilitated transfer of glucose from blood into brain tissue.

1965 • 441 citations

Adenyl Cyclase

1962 • 415 citations

Levels of enzymes of the direct oxidative pathway of carbohydrate metabolism in mammalian tissues and tumours

1954 • 415 citations

Control of Energy Metabolism

1965 • 413 citations

A STUDY OF EXTRACELLULAR SPACE IN CENTRAL NERVOUS TISSUE BY FREEZE-SUBSTITUTION

1965 • 404 citations

Effects of Changes in Brain Metabolism on the Levels of Citric Acid Cycle Intermediates

1966 • 396 citations

Mitochondrial Hexokinase

1967 • 391 citations

The intracellular distribution of glycolytic and other enzymes in rat-brain homogenates and mitochondrial preparations

1960 • 370 citations

ARTERIAL AND CEREBRAL VENOUS BLOOD

1942 • 356 citations

Kinetic Evidence for Multiple Binding Sites on Phosphofructokinase

1966 • 336 citations

Regulatory Mechanisms in Carbohydrate Metabolism

1965 • 315 citations

Levels of oxidized and reduced diphosphopyridine nucleotide and triphosphopyridine nucleotide in animal tissues

1955 • 291 citations

THE NON-COMPETITIVE INHIBITION OF BRAIN HEXOKINASE BY GLUCOSE-6-PHOSPHATE AND RELATED COMPOUNDS

1954 • 277 citations

Practical Neurochemistry

1963 • 272 citations

P-Fructokinase and the control of the citric acid cycle

1963 • 272 citations

PYRIDINE NUCLEOTIDE TRANSHYDROGENASE

1953 • 240 citations

The sodium-stimulated adenosine-triphosphatase activity and other properties of cerebral microsomal fractions and subfractions

1962 • 237 citations

Studies on sodium-potassium-activated adenosinetriphosphatase. V. Correlation of enzyme activity with cation flux in six tissues

1963 • 235 citations

Distribution of Blood (Fe ⁵⁹ ) and Plasma (I ¹³¹ ) Volumes of Rats Determined by Liquid Nitrogen Freezing

1956 • 233 citations

THE EFFECT OF ADRENAL CORTEX AND ANTERIOR PITUITARY EXTRACTS AND INSULIN ON THE HEXOKINASE REACTION

1947 • 195 citations

Glycogen Metabolism

1960 • 187 citations

A comparative study of the aqueous humour and cerebrospinal fluid in the rabbit

1955 • 181 citations

THE QUANTITATIVE HISTOCHEMISTRY OF THE BRAIN

1958 • 179 citations

THE KINETICS OF THE ENZYMATIC SYNTHESIS OF GLYCOGEN FROM GLUCOSE-1-PHOSPHATE

1940 • 173 citations

THE ROLE OF CO₂ FIXATION IN CARBOHYDRATE UTILIZATION AND SYNTHESIS

1959 • 171 citations

Levels of activity of the enzymes of the glycogen cycle in rat tissues

1960 • 164 citations

Carbon Dioxide Fixation in the Brain

1962 • 161 citations

FRUCTOSE 1, 6-DIPHOSPHATASE IN STRIATED MUSCLE

1965 • 156 citations

Regulation of Glucose Uptake in Muscle

1961 • 151 citations

Kinetic Studies of the Brain Hexokinase Reaction

1962 • 150 citations

Active Cation Transport as a Pace-maker of Respiration

1961 • 140 citations

QUANTITATIVE ASPECTS OF CO₂ FIXATION IN MAMMALIAN BRAIN IN VIVO*

1964 • 139 citations

Changes in d(-)-β-Hydroxybutyric Dehydrogenase Activity during Brain Maturation in the Rat

1967 • 138 citations

Carrier transport of glucose between blood and cerebrospinal fluid

1964 • 137 citations

STOFFWECHSELVORGÄNGE IM GEHIRN BEI NORMALER UND HERABGESETZTER KÖRPERTEMPERATUR UNTER ISCHAMISCHER UND ANOXISCHER BELASTUNG*†

1958 • 128 citations

THE METABOLISM OF GLUTAMATE IN HOMOGENATES AND SLICES OF BRAIN CORTEX

1963 • 127 citations

Membrane potentials in mammalian cerebral tissues in vitro: dependence on ionic environment

1961 • 122 citations

STUDIES ON THE ENZYME ENOLASE

1957 • 119 citations

The Kinetics of Glycogen Phosphorylases from Brain and Muscle

1967 • 112 citations

Continuous recording of changes in membrane potential in mammalian cerebral tissues in vitro; recovery after depolarization by added substances

1965 • 110 citations

The physiological role of the ketone bodies

1961 • 110 citations

Electrolyte distribution in mammalian central nervous system: Are glia high sodium cells?

1961 • 109 citations

Phosphorolysis and synthesis of glycogen in animal tissues

1943 • 109 citations

THE FORMATION OF GLUCOSE-1-PHOSPHORIC ACID IN EXTRACTS OF MAMMALIAN TISSUES AND OF YEAST

1938 • 105 citations

THE SODIUM, POTASSIUM AND CHLORIDE OF CEREBRAL TISSUES: MAINTENANCE, CHANGE ON STIMULATION AND SUBSEQUENT RECOVERY

1965 • 96 citations

Excitatory acidic amino acids and the cation content and sodium ion flux of isolated tissues from the brain

1968 • 96 citations

A Comparison of Products Obtained by Various Procedures Used for the Extraction of Glycogen

1964 • 96 citations

THE CARBOHYDRATE METABOLISM OF BRAIN

1936 • 95 citations

Metabolism of the Nervous System

1958 • 93 citations

A Mild Procedure for the Isolation of Polydisperse Glycogen from Animal Tissues

1964 • 93 citations

Variation of cerebral cortex fluid spaces in vivo as a function of species brain size

1965 • 93 citations

THE CARBOHYDRATE METABOLISM OF BRAIN

1936 • 91 citations

EFFECT OF CONVULSIVE ACTIVITY UPON THE CONCENTRATION OF BRAIN GLUCOSE, GLYCOGEN, LACTATE, AND PHOSPHATES

1947 • 89 citations

GLYCOGEN PHOSPHORYLASE IN BRAIN*

1962 • 89 citations

IONIC BASIS FOR THE DEPOLARIZATION OF CEREBRAL TISSUES BY EXCITATORY ACIDIC AMINO ACIDS

1966 • 89 citations

The resynthesis of glycogen by guinea pig cerebral-cortex slices

1955 • 87 citations

SUBSTRATE CHANGES IN PERIPHERAL NERVE DURING ISCHAEMIA and WALLERIAN DEGENERATION*

1965 • 86 citations

GLUCOSE METABOLISM IN BRAIN TISSUE: THE HEXOSEMONOPHOSPHATE SHUNT AND ITS ROLE IN GLUTATHIONE REDUCTION

1962 • 81 citations

Ultrastructural appearance of glycogen in the B-neurons of the lumbar spinal ganglia of the frog

1966 • 81 citations

Cerebral Metabolism of Isotopic Glucose in Normal Human Subjects

1957 • 80 citations

THE INHIBITION OF BRAIN HEXOKINASE BY ADENOSINEDIPHOSPHATE AND SULFHYDRYL REAGENTS

1954 • 80 citations

Pyruvate oxidation in brain

1939 • 78 citations

The concentration of glucose in rat tissues

1956 • 77 citations

STUDIES OF RADIOACTIVE INJECTED LABELED INSULIN

1954 • 73 citations

MECHANISM OF INHIBITION OF ANAEROBIC GLYCOLYSIS OF BRAIN BY SODIUM IONS

1950 • 71 citations

MEMBRANE POTENTIALS IN ISOLATED AND ELECTRICALLY STIMULATED MAMMALIAN CEREBRAL CORTEX. EFFECTS OF CHLORPROMAZINE, COCAINE, PHENOBARBITONE AND PROTAMINE ON THE TISSUE'S ELECTRICAL AND CHEMICAL RESPONSES TO STIMULATION

1963 • 71 citations

The subcellular distribution and properties of hexokinases in the guinea-pig cerebral cortex

1967 • 70 citations

BIOCHEMICAL AND PHYSIOLOGICAL DIFFERENTIATION DURING MORPHOGENESIS‐XXIII. FURTHER OBSERVATIONS RELATING TO THE SYNTHESIS OF AMINO ACIDS AND PROTEINS BY THE CEREBRAL CORTEX AND LIVER OF THE MOUSE*

1959 • 70 citations

GLYCEROL PHOSPHATE DEHYDROGENASE ACTIVITY OF DEVELOPING RAT CENTRAL NERVOUS SYSTEM*

1962 • 69 citations

Effects of some inorganic salts on the metabolic response of sections of mammalian cerebral cortex to electrical stimulation

1952 • 69 citations

STUDIES ON THE PHOSPHORUS COMPOUNDS OF BRAIN

1935 • 69 citations

Glycerol as a Substrate for Brain Metabolism

1966 • 65 citations

The sodium and other ions of mammalian cerebral tissues, maintained and electrically stimulated in vitro

1962 • 64 citations

Effects of neurotropic drugs on glucose metabolism in rat brain in vivo

1966 • 62 citations

ISOLATION FROM RAT BRAIN OF MITOCHONDRIA DEVOID OF GLYCOLYTIC ACTIVITY*

1963 • 62 citations

Glycogen Synthesis from Uridine Diphosphate Glucose in Brain

1960 • 59 citations

EVIDENCE OF MEDIATED TRANSFER OF MONOSACCHARIDES FROM BLOOD TO BRAIN IN RODENTS

1966 • 58 citations

THE CALCIUM CONTENT OF ISOLATED CEREBRAL TISSUES AND THEIR STEADY‐STATE EXCHANGE OF CALCIUM*

1963 • 58 citations

The glucose, glycogen and aerobic glycolysis of isolated cerebral tissues

1956 • 56 citations

Glucose oxidation by brain mitochondria

1956 • 55 citations

THE EFFECT OF HYPOGLYCEMIA ON THE METABOLISM OF THE BRAIN1

1937 • 54 citations

Catabolism of Glucose by Mammalian Tissues

1955 • 52 citations

EFFECT OF CONVULSANTS ON BRAIN GLYCOGEN IN THE MOUSE*

1961 • 52 citations

CHANGES OF BRAIN GLYCOGEN IN THE SPREADING EEG—DEPRESSION OF LEAO

1958 • 50 citations

Glucose Metabolism in Rat Brain In Vivo

1962 • 49 citations

Glutamic acid, other amino acids and related compounds as substrates for cerebral tissues: their effects on tissue phosphates

1961 • 49 citations

INSULIN SENSITIVITY OF THE HUMAN BRAIN

1966 • 48 citations

Central Nervous Function and Changes in Brain Metabolite Concentration

1950 • 48 citations

THE CARBOHYDRATE METABOLISM OF BRAIN

1937 • 45 citations

Factors affecting the glucose 6-phosphate inhibition of hexokinase from cerebral cortex tissue of the guinea pig

1968 • 44 citations

BRAIN MITOCHONDRIA

1963 • 40 citations

DER EINFLUSS VON PROPRANOLOL AUF DIE DURCH METHAMPHETAMIN VERURSACHTEN ÄNDERUNGEN VON FUNKTION UND STOFFWECHSEL DES GEHIRNS *

1967 • 39 citations

Biochemistry and the Central Nervous System

1967 • 38 citations

Chemical Exploration of the Brain: A Study of Cerebral Excitability and Ion Movement.

1963 • 37 citations

THE CARBOHYDRATE METABOLISM OF BRAIN III. ON THE ORIGIN OF LACTIC ACID

1937 • 37 citations

Method for simultaneous quantitative estimation of intracranial contents

1961 • 37 citations

GLYCOLYTIC ACTIVITY ASSOCIATED WITH RAT BRAIN MITOCHONDRIA

1959 • 36 citations

Activation and Solubilization of Particle-Bound Hexokinase in Rat Brain

1967 • 35 citations

THE QUANTITATIVE HISTOCHEMISTRY OF THE BRAIN ENZYMES OF GLYCOGEN METABOLISM*

1961 • 35 citations

Notizen: Versuche zum Mechanismus der Pasteur-Reaktion. Der Einfluß von Phosphationen auf die Aktivität der strukturgebundenen Hexokinase

1959 • 35 citations

Effect of potassium and ammonium ions upon glycolysis catalyzed by an extract of rat brain

1951 • 35 citations

Glycolytic metabolites and co-factors in human cerebral cortex and white matter during complete ischemia

1967 • 33 citations

Effect of Chlorpromazine, Ether, and Phenobarbital on the Active-Phosphate Level of Rat Brain: an Improved Extraction Technique for Acid-soluble Phosphates

1962 • 31 citations

Extraction of glycogen with dimethyl sulfoxide

1962 • 31 citations

ALTERNATE GLYCOLYTIC PATHWAYS IN BRAIN

1965 • 31 citations

OXIDATION OF GLUCOSE IN A MAMMALIAN SYMPATHETIC GANGLION AT REST AND IN ACTIVITY*

1962 • 30 citations

IRREVERSIBLE POST-HYPOGLYCEMIC COMA

1951 • 30 citations

Mechanism of Sugar Transport in Brain Slices

1965 • 29 citations

The speed of several cerebral reactions involving the nicotinamide coenzymes

1957 • 28 citations

THE ACTIVITY OF URIDINE DIPHOSPHATE GLUCOSE-GLYCOGEN SYNTHETASE IN SOME EMBRYONIC TISSUES

1964 • 27 citations

Studies on a direct effect of insulin on the central nervous system: a review.

1961 • 25 citations

On the mechanism of the inhibition of glycolysis by glyceraldehyde

1951 • 25 citations

THE EFFECT OF PERIODIC CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE ON THE GLYCOGEN OF RAT BRAIN

1965 • 25 citations

Purification of uridine diphosphoglucose-glycogen transglucosylase from sheep brain

1961 • 24 citations

Effect of inhibitors on the metabolism of specifically labelled glucose by brain

1960 • 24 citations

Lactic dehydrogenase isozymes in the nervous tissue I. The reaction of isozymes with diphosphopyridine nucleotide analogues and their inhibition by sodium metabisulfite

1962 • 24 citations

The incorporation of isotopic carbon (14C) into the cerebral glycogen of rabbits

1965 • 23 citations

PHOSPHORYLASEAKTIVITÄT UND GLYKOGENGEHALT DES GEHIRNS UNTER DEM EINFLUSS VON ÄTHANOL UND ADRENALIN THE EFFECT OF ETHANOL AND ADRENALINE ON THE PHOSPHORYLASE ACTIVITY AND GLYCOGEN CONTENT OF THE BRAIN

1965 • 22 citations

The purification of enolase from cerebral tissue

1964 • 20 citations

Identification of fructose in mammalian nerve

1964 • 20 citations

The point of the aerobic inhibition of glycolytic activity associated with brain mitochondria

1959 • 20 citations

Tetrodotoxin and the cation content, excitability and metabolism of isolated mammalian cerebral tissues

1967 • 19 citations

GLYCOGEN SYNTHESIS IN BRAIN CORTEX SLICES AND SOME FACTORS AFFECTING IT

1957 • 17 citations

Inhibitors and activators of brain hexokinase

1954 • 17 citations

Glucose Metabolism and α-Keto-acids in Rat Brain and Liver in vivo

1965 • 16 citations

Encephalic glycogen differences in young and adult rats

1961 • 16 citations

Activators and Inhibitors of Hexokinase in Human Blood

1951 • 15 citations

PURIFICATION OF URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE FROM HUMAN BRAIN*

1961 • 14 citations

Effect of insulin on the glycogen synthesis in vivo in the brain and liver of rats under different conditions.

1965 • 14 citations

Interrelationship between Glucose Utilization of Brain and Heart

1963 • 12 citations

Recognition and Solubilization of Glucose 6-Phosphate and 6-Phosphogluconate Dehydrogenases in the Particle Fractions of Brain

1962 • 11 citations

A Method for Unravelling Complex Spectra

1962 • 11 citations

BRAIN GLYCOGEN IN THE FED AND FASTING STATE.

1963 • 11 citations

The hexose specificity of hexokinase in brain from various species

1957 • 10 citations

Effect of Stress on Glycogen and Phosphorylase in the Rat Anterior Pituitary

1964 • 10 citations

Brain NADH-tetraazolium reductase activity, lipoamide dehydrogenase and activating lipids

1963 • 10 citations

Higher Glucose Affinity of Hexokinase in Sheep Brain than in Rat Brain

1966 • 9 citations

Blood and cerebrospinal fluid glucose in the fasting state

1960 • 9 citations

Normal and Seizure Levels of Lactate, Pyruvate and Acid-Soluble Phosphates in the Cerebellum and Cerebrum.

1949 • 9 citations

Actions of haloperidol, meperidine, and related compounds on the excitability and ion content of isolated cerebral tissue

1964 • 8 citations