Chemotherapy of small-cell lung cancer.

Dose: A critical factor in cancer chemotherapy

1980 • 851 citations

Rationale for the use of alternating non-cross-resistant chemotherapy.

1982 • 545 citations

Tumor size, sensitivity to therapy, and design of treatment schedules.

1977 • 442 citations

cis-Dichlorodiammineplatinum(II): combination chemotherapy and cross-resistance studies with tumors of mice.

1979 • 405 citations

Intensive chemotherapy of small cell bronchogenic carcinoma.

1977 • 253 citations

A randomized combined modality trial in small cell carcinoma of the lung comparison of combination chemotherapy-radiation therapy versus cyclophosphamide-radiation therapy effects of maintenance chemotherapy and prophylactic whole brain irradiation

1980 • 210 citations

Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.

1985 • 188 citations

cis-Dichlorodiammineplatinum(II) and VP-16-213: an active induction regimen for small cell carcinoma of the lung.

1979 • 153 citations

Small-Cell Lung Cancer

1979 • 133 citations

Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.

1982 • 131 citations

Small cell lung cancer

1979 • 119 citations

Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.

1984 • 114 citations

Long-term results in combined-modality treatment of small cell carcinoma of the lung.

1978 • 112 citations

The superiority of combination chemotherapy over single agent chemotherapy in small cell lung carcinoma

1979 • 111 citations

Chemotherapy of Advanced Small-Cell Anaplastic Carcinoma

1978 • 110 citations

Combination Chemotherapy and Radiation Therapy for Small Cell Carcinoma

1977 • 78 citations

“Total” Therapy for Small Cell Carcinoma of the Lung

1978 • 74 citations

Small Cell Bronchogenic Carcinoma: A Review of Therapeutic Results

1981 • 74 citations

VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer

1984 • 68 citations

Cisplatin, adriamycin, and etoposide (cav) for remission induction of small-cell bronchogenic carcinoma. Evaluation of efficacy and toxicity and pilot study of a “late intensification” with autologous bone-marrow rescue

1982 • 67 citations

Continuous versus alternating combination chemotherapy for advanced small cell carcinoma of the lung.

1983 • 66 citations

Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.

1973 • 64 citations

Combined Modality Treatment of Small Cell Carcinoma of the Lung

1981 • 61 citations

Intensive chemoradiotherapy with autologous marrow transplantation for small cell carcinoma of the lung.

1983 • 57 citations

Randomized study of high-dose versus low-dose methotrexate in the treatment of extensive small cell lung cancer

1982 • 57 citations

Concepts for controlling drug-resistant tumor cells.

1980 • 50 citations

Late intensification in small-cell lung cancer: a phase I study of high doses of cyclophosphamide and etoposide with autologous bone marrow transplantation.

1985 • 49 citations

Treatment of extensive stage small cell bronchogenic carcinoma

1983 • 48 citations

Cyclophosphamide and VP 16-213 with autologous bone marrow transplantation. A dose escalation study

1984 • 44 citations

Intensive induction chemotherapy in 54 patients with small cell carcinoma of the lung.

1981 • 39 citations

Multicenter Phase II trial of etoposide in refractory small cell lung cancer.

1985 • 38 citations

Extensive-stage small-cell bronchogenic carcinoma: intensive induction chemotherapy with high-dose cyclophosphamide plus high-dose etoposide.

1985 • 38 citations

Intermittent high-dose cyclophosphamide chemotherapy for small cell carcinoma of the lung.

1978 • 36 citations

Phase III study of CCNU, cyclophosphamide, adriamycin, vincristine, and VP-16 in small-cell carcinoma of the lung

1982 • 36 citations

High-dose cyclophosphamide (7 g/m2) with or without autologous bone marrow rescue after conventional chemotherapy in the treatment of patients with small cell lung cancer

1983 • 23 citations

Effects of intensive induction chemotherapy for extensive-disease small cell bronchogenic carcinoma in protected environment-prophylactic antibiotic units

1984 • 21 citations

VP-16-213 therapy in patients with small-cell carcinoma of the lung after failure on combination chemotherapy.

1981 • 20 citations

CCNU, vincristine, methotrexate, and procarbazine treatment of relapsed small cell lung carcinoma.

1982 • 20 citations

Chemotherapy of small cell carcinoma of the lung: Comparison of a cyclic alternative combination with simultaneous combinations of four and seven agents

1981 • 20 citations

Evaluation of the survival gain in 22 measurable lung tumors treated with chemotherapy

1969 • 17 citations

Phase II study of procarbazine in small cell carcinoma of the lung.

1982 • 13 citations

Alternating non-cross-resistant drug combinations in the treatment of metastatic small-cell carcinoma of the lung.

1981 • 13 citations

Reinduction prolongs survival in complete responders (CR) with small cell lung cancer

1982 • 7 citations