Structure and Replication of the Alphavirus Genome

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

Methods of Enzymology.

1956 • 1,750 citations

[31] Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acids

1971 • 1,605 citations

Rapid Evolution of RNA Genomes

1982 • 1,475 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

Codon catalog usage is a genome strategy modulated for gene expressivity

1981 • 951 citations

Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses

1984 • 830 citations

Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells

1981 • 686 citations

Nucleotide sequence of tobacco mosaic virus RNA.

1982 • 685 citations

Nucleotide sequence heterogeneity of an RNA phage population

1978 • 557 citations

Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus

1983 • 464 citations

Nucleotide sequence of cDNA coding for Semliki Forest virus membrane glycoproteins

1980 • 428 citations

Complete nucleotide sequence of the genomic RNA of Sindbis virus

1984 • 393 citations

Leaky UAG termination codon in tobacco mosaic virus RNA

1978 • 316 citations

Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins.

1981 • 304 citations

Multicomponent RNA plant virus infection derived from cloned viral cDNA

1984 • 300 citations

Striking similarities in amino acid sequence among nonstructural proteins encoded by RNA viruses that have dissimilar genomic organization.

1984 • 235 citations

Virus Structure and Assembly

1985 • 232 citations

Non-neutralizing monoclonal antibodies can prevent lethal alphavirus encephalitis

1982 • 227 citations

Cytoplasmic Structures Associated with an Arbovirus Infection: Loci of Viral Ribonucleic Acid Synthesis

1968 • 218 citations

Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses

1985 • 205 citations

The nucleotide sequence at the origin for assembly on tobacco mosaic virus RNA

1977 • 191 citations

Nucleotide sequence of the brome mosaic virus genome and its implications for viral replication

1984 • 183 citations

Assembly of the semliki forest virus membrane glycoproteins in the membrane of the endoplasmic reticulum in vitro

1978 • 178 citations

Rubella virus contains one capsid protein and three envelope glycoproteins, E1, E2a, and E2b

1983 • 176 citations

Translocation of proteins across membranes: the signal hypothesis and beyond.

1979 • 176 citations

Doublet frequency analysis of fractionated vertebrate nuclear DNA

1976 • 172 citations

Natural Read-through at the UGA Termination Signal of Qβ Coat Protein Cistron

1971 • 171 citations

Replication of Sindbis virus

1972 • 167 citations

Cleavage of Rous sarcoma viral polypeptide precursor into internal structural proteins in vitro involves viral protein p15.

1977 • 167 citations

Sindbis virus infection of chick and hamster cells: Synthesis of virus-specific proteins

1969 • 166 citations

Complementation between temperature-sensitive mutants of Sindbis virus

1966 • 164 citations

Isolation and characterization of the membrane proteins of Semliki Forest virus

1974 • 164 citations

Translation of the UGA triplet in vitro by tryptophan transfer RNA's

1971 • 162 citations

Homologous sequences in non-structural proteins from cowpea mosaic virus and picornaviruses

1984 • 156 citations

A UGA termination suppression tRNATrp active in rabbit reticulocytes

1980 • 150 citations

Immediate glycosylation of Sindbis virus membrane proteins

1977 • 150 citations

Defective Interfering RNA Viruses and the Host-Cell Response

1980 • 148 citations

Complete sequences of the intergenic and mRNA start signals in the Sendai virus genome: homologies with the genome of vesicular stomatitis virus

1984 • 146 citations

Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon

1981 • 146 citations

Sequence coding for the alphavirus nonstructural proteins is interrupted by an opal termination codon.

1983 • 145 citations

The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region.

1980 • 144 citations

Translation of Sindbis virus 26 S RNA and 49 S RNA in lysates of rabbit reticulocytes

1974 • 144 citations

Identification of a second glycoprotein in Sindbis virus

1972 • 143 citations

Protease required for processing picornaviral coat protein resides in the viral replicase gene

1979 • 142 citations

Antigenic characterization of two Sindbis envelope glycoproteins separated by isoelectric focusing

1976 • 136 citations

Identification of the membrane protein and "core" protein of Sindbis virus.

1968 • 135 citations

Evidence for an autoprotease activity of sindbis virus capsid protein

1978 • 134 citations

Association of Sindbis virion glycoproteins and their precursors

1982 • 133 citations

Monoclonal Antibodies to Sindbis Virus Glycoprotein E1 can Neutralize, Enhance Infectivity, and Independently Inhibit Haemagglutination or Haemolysis

1982 • 128 citations

Sequence relationships between the genome and the intracellular RNA species of standard and defective-interfering semliki forest virus

1976 • 126 citations

Structural proteins of Chikungunya virus

1984 • 126 citations

How a single sindbis virus mRNA directs the synthesis of one soluble protein and two integral membrane glycoproteins

1977 • 124 citations

Ross river virus 26 S RNA: Complete nucleotide sequence and deduced sequence of the encoded structural proteins

1983 • 123 citations

Requirement of 3′-Terminal Poly(adenylic acid) for the Infectivity of Poliovirus RNA

1974 • 122 citations

Rubella virus 40S genome RNA specifies a 24S subgenomic mRNA that codes for a precursor to structural proteins

1984 • 121 citations

Formation of the Semliki Forest Virus Membrane Glycoprotein Complexes in the Infected Cell

1980 • 117 citations

Replication of Sindbis virus

1972 • 116 citations

Complete nucleotide sequence of alfalfa mosaic virus RNA 4

1980 • 116 citations

Specific Sindbis virus-coded function for minus-strand RNA synthesis

1981 • 116 citations

RNAs from two independently isolated defective interfering particles of Sindbis virus contain a cellular tRNA sequence at their 5' ends.

1983 • 114 citations

Replication Strategies of the Single Stranded RNA Viruses of Eukaryotes

1983 • 110 citations

Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA.

1982 • 109 citations

Short-lived minus-strand polymerase for Semliki Forest virus

1980 • 109 citations

Proposed Antigenic Classification of Registered Arboviruses I. Togaviridae, <i>Alphavirus</i>

1980 • 109 citations

Membrane-Associated Replication Complex in Arbovirus Infection

1972 • 107 citations

Large-Molecular-Weight Precursors of Sindbis Virus Proteins

1973 • 104 citations

Specific Membranous Structures Associated with the Replication of Group A Arboviruses

1972 • 103 citations

The Evolution of RNA Viruses

1982 • 102 citations

The extraction of infectious virus nucleic acid with hot phenol

1959 • 100 citations

The 5′-terminal sequences of the genomic RNAs of several alphaviruses

1983 • 99 citations

The 3′-non-coding regions of alpharivus RNAs contain repeating sequences

1982 • 98 citations

Studies in subviral components of Semliki Forest virus.

1969 • 98 citations

Comparative studies of the 3′-terminal sequences of several alphavirus RNAs

1981 • 98 citations

Reconstitution of tobacco mosaic virus rods occurs bidirectionally from an internal initiation region: demonstration by electron microscopic serology.

1977 • 94 citations

Mutants of Sindbis virus

1976 • 93 citations

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions

1985 • 89 citations

Complete nucleotide sequence of alfalfa mosaic virus RNA 1

1983 • 87 citations

Morphogenesis of Sindbis virus in cultured Aedes albopictus cells

1975 • 87 citations

Absence of a cleavable signal sequence in Sindbis virus glycoprotein PE2.

1979 • 85 citations

Functional defects of RNA-negative temperature-sensitive mutants of Sindbis and Semliki Forest viruses

1979 • 85 citations

Membrane biogenesis. In vitro cleavage, core glycosylation, and integration into microsomal membranes of sindbis virus glycoproteins.

1979 • 85 citations

Complete nucleotide sequence of alfalfa mosaic virus RNA 2

1983 • 81 citations

Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease.

1985 • 81 citations

The gene order for rubella virus structural proteins is NH2-C-E2-E1-COOH

1984 • 81 citations

An Electron Microscope Study of Sindbis Virus RNA

1974 • 81 citations

Isolation and characterization of the hydrophobic COOH-terminal domains of the Sindbis virion glycoproteins

1982 • 79 citations

Replication of semliki forest virus: polyadenylate in plus-strand RNA and polyuridylate in minus-strand RNA

1976 • 79 citations

Sindbis virus messenger RNA: the 5′-termini and methylated residues of 26 and 42 S RNA

1977 • 78 citations

Replicative form of Semliki Forest virus RNA contains an unpaired guanosine

1979 • 77 citations

Sequential translation of nonstructural proteins in cells infected with a Semliki Forest virus mutant.

1976 • 76 citations

A sindbis virus mutant temperature-sensitive in the regulation of minus-strand RNA synthesis

1981 • 76 citations

Functional defects of temperature-sensitive mutants of Sindbis virus

1968 • 75 citations

Semliki Forest virus capsid protein associates with the 60S ribosomal subunit in infected cells

1976 • 74 citations

The amphiphilic membrane glycoproteins of Semliki forest virus are attached to the lipid bilayer by their COOH-terminal ends

1978 • 74 citations

Purification and Polypeptide Composition of Semliki Forest Virus RNA Polymerase

1976 • 74 citations

Two small virus-specific polypeptides are produced during infection with Sindbis virus

1979 • 72 citations

Defects in RNA+ temperature-sensitive mutants of Sindbis virus and evidence for a complex of PE2-E1 viral glycoproteins

1976 • 69 citations

The generation and propagation of defective-interfering particles of semliki forest virus in different cell types

1978 • 68 citations

18S defective interfering RNA of Semliki Forest virus contains a triplicated linear repeat.

1981 • 68 citations

Tryptic peptide analysis on nonstructural and structural precursor proteins from Semliki Forest virus mutant-infected cells

1975 • 66 citations

Solubilization of the semliki forest virus membrane with sodium deoxycholate

1976 • 65 citations

5′ Nucleotide Sequence of Sindbis Viral RNA

1976 • 65 citations

Translation and Processing of Alphavirus Proteins

1980 • 63 citations

Di- and trimethylated congeners of 7-methylguanine in Sindbis virus mRNA

1976 • 62 citations

Functional analysis of the a complementation group mutants of sindbis HR virus

1985 • 61 citations

Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus

1981 • 61 citations

Ross River Virus Replication in Cultured Mosquito and Mammalian Cells: Virus Growth and Correlated Ultrastructural Changes

1973 • 59 citations

Translation of Semliki-Forest-Virus Intracellular 26-S RNA. Characterisation of the Products Synthesized in vitro

1975 • 59 citations

Semliki forest virus mutants with temperature-sensitive transport defect of envelope proteins

1980 • 58 citations

Homology between the glycoproteins of vesicular stomatitis virus and rabies virus

1982 • 58 citations

Ribonucleic Acid Polymerase Catalyzing Synthesis of Double-stranded Arbovirus Ribonucleic Acid

1967 • 57 citations

The core protein of the alphavirus sindbis virus assembles into core-like nucleoproteins with the viral genome RNA and with other single-stranded nucleic acids in vitro

1982 • 57 citations

Evidence for a separate signal sequence for the carboxy-terminal envelope glycoprotein E1 of Semliki forest virus

1981 • 57 citations

Solubilized RNA replication complex from Semliki Forest virus-infected cells

1979 • 55 citations

Extreme ends of the genome are conserved and rearranged in the defective interfering RNAs of semliki forest virus

1982 • 55 citations

Infection of neuroblastoma cells by Semliki Forest virus. The interference of viral capsid protein with the binding of host messenger RNAs into initiation complexes is the cause of the shut-off of host protein synthesis

1984 • 54 citations

Mechanism for Control of Synthesis of Semliki Forest Virus 26S and 42S RNA

1978 • 52 citations

Kinetics of Formation of the Semliki Forest Virus Nucleocapsid

1973 • 52 citations

Sequence analysis of cDNA's derived from the RNA of Sindbis virions and of defective interfering particles

1982 • 52 citations

Nonstructural proteins of Semliki Forest virus: synthesis, processing, and stability in infected cells

1983 • 51 citations

Identification of a unique guanine-7-methyltransferase in Semliki forest virus (SFV) infected cell extracts

1983 • 50 citations

Biochemical studies of the maturation of the small sindbis virus glycoprotein E3

1984 • 49 citations

Expression of the structural proteins of Semliki Forest virus from cloned cDNA microinjected into the nucleus of baby hamster kidney cells.

1982 • 48 citations

Primary structures of the core proteins of the alphaviruses semliki forest virus and sindbis virus

1981 • 48 citations

Interaction of Sindbis virus glycoproteins during morphogenesis

1977 • 47 citations

Togaviruses in Cultured Arthropod Cells

1980 • 47 citations

Biochemical and Antigenic Comparisons of the Envelope Glycoproteins of Venezuelan Equine Encephalomyelitis Virus Strains

1979 • 46 citations

Mutants of Alphaviruses: Genetics and Physiology

1980 • 45 citations

Replication of Sindbis virus

1973 • 45 citations

Protease of adenovirus type 2: Partial characterization

1979 • 45 citations

RNA Polymerase Components in Semliki Forest Virus-Infected Cells: Synthesis from Large Precursors

1976 • 44 citations

Effects of Different RNAs and Components of the Cell-Free System on In Vitro Synthesis of Sindbis Viral Proteins

1974 • 43 citations

Kinetics of biphasic reconstitution of tobacco mosaic virus in vitro.

1978 • 42 citations

Studies of defective interfering RNAs of Sindbis virus with and without tRNAAsp sequences at their 5' termini

1985 • 41 citations

The requirement of nonsense suppression for the development of several phages

1979 • 39 citations

Characterization and nucleotide sequence of a chicken gene encoding an opal suppressor tRNA and its flanking DNA segments.

1983 • 39 citations

Heterogeneity in the poly(A) content of the genome of sindbis virus

1972 • 38 citations

Synthesis of Sindbis virus nonstructural polypeptides in chicken embryo fibroblasts

1977 • 37 citations

Temperature-sensitive host-dependent mutants of Sindbis virus

1981 • 37 citations

Synthesis and processing of sindbis virus nonstructural proteins in vitro

1982 • 37 citations

Biophysical studies on circle formation by Sindbis virus 49 S RNA

1979 • 36 citations

A study of nucleotide sequence homology between the nucleic acids of different alphaviruses

1977 • 36 citations

Semliki Forest Virus Replication Complex Capable of Synthesizing 42S and 26S Nascent RNA Chains

1980 • 35 citations

Amino-terminal sequence analysis of the structural proteins of Sindbis virus.

1978 • 35 citations

Replication of sindbis virus VI. Poly(A) and poly(U) in virus-specific RNA species

1978 • 34 citations

Requirement for host transcription in the replication of Sindbis virus

1983 • 34 citations

Mutants of Sindbis virus. III. Host polypeptides present in purified HR and ts103 virus particles

1978 • 34 citations

Semliki Forest Virus-Specific RNAs Synthesized In Vitro by Enzyme from Infected BHK Cells

1973 • 33 citations

An adenylate-rich segment in the virion RNA of sindbis virus

1972 • 33 citations

Mutants of sindbis virus II. Characterization of a maturation-defective mutant, ts103

1977 • 33 citations

Sindbis Virus-induced Viral Ribonucleic Acid Polymerase

1969 • 33 citations

Synthesis of Alphavirus-Specified RNA

1978 • 31 citations

Sequence analysis of two mutants of sindbis virus defective in the intracellular transport of their glycoproteins

1983 • 30 citations

Formation of a Sindbis virus nonstructural protein and its relation of 42S mRNA function

1976 • 29 citations

An evolutionary tree relating eight alphaviruses, based on amino-terminal sequences of their glycoproteins.

1984 • 28 citations

Cleavage Defect in the Non-structural Polyprotein of Semliki Forest Virus has Two Separate Effects on Virus RNA Synthesis

1978 • 27 citations

The Assembly of Alphaviruses

1980 • 27 citations

The nonstructural proteins of sindbis virus as studied with an antibody specific for the C terminus of the nonstructural readthrough polyprotein

1985 • 26 citations

Virus-directed post-translational cleavage in Sindbus virus-infected cells

1977 • 24 citations

Amino-terminal sequence analysis of alphavirus polypeptides

1981 • 22 citations

Studies on the polyribosome-associated RNA in BHK21 cells infected with Semliki Forest virus

1974 • 22 citations

Comparative electrophoretic studies on the structural proteins of selected group a arboviruses

1974 • 21 citations

Concomitant methylation and synthesis in vitro of semliki forest virus (SFV) ss RNAs by a fraction from infected cells

1981 • 18 citations

In vivo NH2-terminal acetylation of Sindbis virus proteins.

1981 • 17 citations

Sindbis virus I. Gene order of translation in Vivo

1980 • 17 citations

Nucleotide sequence at the junction between the nonstructural and the structural genes of the semliki forest virus genome

1982 • 16 citations

The N-terminus of PE2 in Sindbis virus-infected cells

1982 • 15 citations

Envelope proteins of Semliki Forest virus synthesized in Xenopus oocytes are transported to the cell surface.

1984 • 13 citations

Nucleoside triphosphate phosphohydrolase produced in BHK cells infected with western equine encephalitis virus is probably associated with the 82K dalton nonstructural polypeptide

1981 • 7 citations

Inhibition of DNA synthesis in BHK cells infected with western equine encephalitis virus 2. Properties of the inhibitory factor of DNA polymerase induced in infected cells

1979 • 6 citations