Cetuximab ameliorates suppressive phenotypes of myeloid antigen presenting cells in head and neck cancer patients

Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck

2006 • 4,800 citations

Macrophage Diversity Enhances Tumor Progression and Metastasis

2010 • 4,601 citations

Protective and pathogenic functions of macrophage subsets

2011 • 4,550 citations

Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer

2008 • 3,395 citations

Coordinated regulation of myeloid cells by tumours

2012 • 3,227 citations

Regulation of immune responses by L-arginine metabolism

2005 • 1,636 citations

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

2010 • 1,410 citations

Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Based Therapy

2007 • 937 citations

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

2008 • 865 citations

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species

2004 • 825 citations

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

2006 • 798 citations

Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

2000 • 685 citations

The function of Fcγ receptors in dendritic cells and macrophages

2014 • 547 citations

Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13

2011 • 543 citations

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

2010 • 512 citations

STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

2013 • 475 citations

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

2013 • 455 citations

The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer

2012 • 450 citations

Population alterations of l-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14−/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer

2009 • 297 citations

Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties

2010 • 295 citations

Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen–Specific T-cell Immunity in Head and Neck Cancer Patients

2013 • 291 citations

Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells

2009 • 253 citations

CTLA-4+ Regulatory T Cells Increased in Cetuximab-Treated Head and Neck Cancer Patients Suppress NK Cell Cytotoxicity and Correlate with Poor Prognosis

2015 • 236 citations

Activation of Tumor-Promoting Type 2 Macrophages by EGFR-Targeting Antibody Cetuximab

2011 • 96 citations

Myeloid-derived suppressor cells in transplantation and cancer

2012 • 78 citations

STAT1-Induced HLA Class I Upregulation Enhances Immunogenicity and Clinical Response to Anti-EGFR mAb Cetuximab Therapy in HNC Patients

2015 • 66 citations

Targeted therapy in head and neck cancer

2008 • 62 citations

Immune biomarkers of anti-EGFR monoclonal antibody therapy

2014 • 46 citations

TLR3 agonists improve the immunostimulatory potential of cetuximab against EGFR⁺head and neck cancer cells

2013 • 45 citations

Interaction of Human Immunoglobulin G with CD16 on Natural Killer Cells: Ligand Clearance, FcgammaRIIIA Turnover and Effects of Metalloproteinases on FcgammaRIIIA-Mediated Binding, Signal Transduction and Killing

2004 • 24 citations

Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: A pilot randomized trial in head and neck cancer

2012 • 11 citations