AIDS AND RELATED SYNDROMES AS A VIRAL-INDUCED AUTOIMMUNE DISEASE OF THE IMMUNE SYSTEM: AN ANTI-MHC II DISORDER. THERAPEUTIC IMPLICATIONS

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome

1983 • 1,625 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

1984 • 976 citations

HTLV-III Infection in Brains of Children and Adults with AIDS Encephalopathy

1985 • 899 citations

Qualitative Analysis of Immune Function in Patients with the Acquired Immunodeficiency Syndrome

1985 • 737 citations

Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency Syndrome

1984 • 639 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts

1985 • 517 citations

Trans -Acting Transcriptional Regulation of Human T-Cell Leukemia Virus Type III Long Terminal Repeat

1985 • 500 citations

Inhibition of Lymphocyte Proliferation by a Synthetic Peptide Homologous to Retroviral Envelope Proteins

1985 • 433 citations

Prolactin receptors on human T and B lymphocytes: antagonism of prolactin binding by cyclosporine.

1985 • 356 citations

A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

1976 • 353 citations

Adaptation of Lymphadenopathy Associated Virus (LAV) to Replication in EBV-Transformed B Lymphoblastoid Cell Lines

1984 • 353 citations

Acid-Labile Human Leukocyte Interferon in Homosexual Men with Kaposi's Sarcoma and Lymphadenopathy

1982 • 327 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

On the Mechanism of Thrombocytopenic Purpura in Sexually Active Homosexual Men

1984 • 311 citations

AIDS — An Immunologic Reevaluation

1984 • 286 citations

Cyclosporin A Binding to Calmodulin: A Possible Site of Action on T Lymphocytes

1985 • 282 citations

Reduced Langerhans’ Cell Ia Antigen and ATPase Activity in Patients with the Acquired Immunodeficiency Syndrome

1984 • 279 citations

Generalized Lymphadenopathy in Homosexual Men

1983 • 273 citations

Three-Year Incidence of AIDS in Five Cohorts of HTLV-III-Infected Risk Group Members

1986 • 272 citations

Influence of the human T-lymphotropic virus/lymphadenopathy-associated virus on functions of human lymphocytes: evidence for immunosuppressive effects and polyclonal B-cell activation by banded viral preparations.

1985 • 213 citations

Patients at Risk for AIDS-Related Opportunistic Infections

1985 • 197 citations

Correlation between immunologic function and clinical subpopulations of patients with the acquired immune deficiency syndrome

1985 • 169 citations

Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy.

1984 • 168 citations

Antibodies to Human T-Lymphotropic Virus Type III and Development of the Acquired Immunodeficiency Syndrome in Homosexual Men Presenting with Immune Thrombocytopenia

1986 • 159 citations

Persistent Noncytopathic Infection of Normal Human T Lymphocytes with AIDS-Associated Retrovirus

1985 • 151 citations

Pathogenesis of visna. II. Effect of immunosuppression upon early central nervous system lesions.

1976 • 114 citations

Reduced ecto-5'-nucleotidase activity and enhanced OKT10 and HLA-DR expression on CD8 (T suppressor/cytotoxic) lymphocytes in the acquired immune deficiency syndrome: evidence of CD8 cell immaturity.

1985 • 108 citations

Decreased expression of human class II antigens on monocytes from patients with acquired immune deficiency syndrome. Increased expression with interferon-gamma.

1984 • 106 citations

Serum suppression of lymphocyte activationin vitro in acquired immunodeficiency disease

1983 • 96 citations

Epidemiology of Human T-Lymphotropic Virus Type III and the Risk of the Acquired Immunodeficiency Syndrome

1985 • 86 citations

HLA-haploidentical bone marrow transplantation for severe combined immunodeficiency using E rosette fractionation and cyclosporine

1986 • 81 citations

Prognostically significant classification of immune changes in AIDS with Kaposi's sarcoma

1986 • 76 citations

Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome.

1985 • 74 citations

Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome

1984 • 72 citations

Lymphocytotoxic antibodies in the acquired immune deficiency syndrome (AIDS)

1984 • 68 citations

Persistent Infection with Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus in Apparently Healthy Homosexual Men

1985 • 63 citations

Retrovirus-mediated immunosuppression. I. FeLV-UV and specific FeLV proteins alter T lymphocyte behavior by inducing hyporesponsiveness to lymphokines.

1985 • 59 citations

Interferon-related Leukocyte Inclusions in Acquired Immune Deficiency Syndrome: Localization in T Cells

1984 • 51 citations

HLA-DR antigens on lymphoid cells differ from those on myeloid cells

1983 • 46 citations

Cellular targets of antilymphocyte antibodies in AIDS and LAS

1985 • 45 citations

Unexplained Persistent Lymphadenopathy in Homosexual Men and the Acquired Immune Deficiency Syndrome

1985 • 36 citations

Lung in acquired immune deficiency syndrome: infectious and immunological status assessed by bronchoalveolar lavage.

1985 • 36 citations

Infection of T4 lymphocytes by HTLV-III does not require expression of the OKT4 epitope.

1986 • 34 citations

THE HISTOPATHOLOGICAL CHANGES IN THE THYMUS GLAND IN THE ACQUIRED IMMUNE DEFICIENCY SYNDROME

1984 • 28 citations

A MULTIFACTORIAL MODEL FOR THE DEVELOPMENT OF AIDS IN HOMOSEXUAL MEN^a

1984 • 23 citations

AUTOANTIBODIES TO T CELLS IN ADULT AND PEDIATRIC AIDS^a

1984 • 21 citations

NONINFECTIOUS COFACTORS IN SUSCEPTIBILITY TO AIDS: POSSIBLE CONTRIBUTIONS OF SEMEN, HLA ALLOANTIGENS, AND LACK OF NATURAL RESISTANCE

1984 • 20 citations

T cell surface antigen expression on lymphocytes of patients with AIDS during in vitro mitogen stimulation

1984 • 10 citations

Side Effects and Safety of Sandimmun� in Long-Term Treatment of Renal Transplant Patients

2015 • 9 citations

HYPOTHESIS: AIDS: A AIDS (AcquiredAutoimmuneImmunodeficiency Syndrome)?

1983 • 4 citations

Deleted Work

1955 • 0 citations