Target size analysis by radiation inactivation of carnitine palmitoyltransferase activity and malonyl-CoA binding in outer membranes from rat liver mitochondria

Methods of Enzymatic Analysis

1974 • 6,512 citations

THE SUBMITOCHONDRIAL LOCALIZATION OF MONOAMINE OXIDASE

1967 • 840 citations

CARNITINE

1988 • 610 citations

Spectrophotometric Assay of Cytochrome c Oxidase

1955 • 503 citations

CHARACTERISTICS OF ISOLATED AND PURIFIED PREPARATIONS OF THE OUTER AND INNER MEMBRANES OF MITOCHONDRIA*

1966 • 366 citations

Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.

1987 • 242 citations

Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. I. Use of inhibitors.

1987 • 183 citations

A neutral metallo endoprotease involved in the processing of an F1-ATPase subunit precursor in mitochondria.

1982 • 167 citations

Identification of 2-tetradecylglycidyl coenzyme A as the active form of methyl 2-tetradecylglycidate (methyl palmoxirate) and its characterization as an irreversible, active site-directed inhibitor of carnitine palmitoyltransferase A in isolated rat liver mitochondria.

1984 • 151 citations

Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. II. Use of detergents and antibodies.

1987 • 149 citations

Carnitine palmitoyltransferase and carnitine octanoyltransferase activities in liver, kidney cortex, adipocyte, lactating mammary gland, skeletal muscle and heart

1981 • 143 citations

Changes in freeze-fractured mitochondrial membranes correlated to their energetic state

1983 • 132 citations

Enrichment and biochemical characterization of boundary membrane contact sites from rat-liver mitochondria

1986 • 117 citations

[6] Molecular weight determinations from radiation inactivation

1985 • 107 citations

Sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo

1982 • 97 citations

Very long chain fatty acid β-oxidation by rat liver mitochondria and peroxisomes

1987 • 95 citations

Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes

1987 • 94 citations

Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes

1985 • 91 citations

Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes

1988 • 86 citations

Size of acetylcholine receptors in the membrane. An improved version of the radiation inactivation method

1982 • 86 citations

Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity

1984 • 67 citations

Sulfhydryl/disulfide forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase.

1985 • 62 citations

Functional size of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase as determined by radiation inactivation.

1985 • 53 citations

Improve method for isolation of rat liver plasma membrane

1976 • 49 citations

Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0°C and 37°C with a fixed concentration of malonyl-CoA

1984 • 46 citations

Carnitine palmitoyltransferase: characterization of a labile detergent-extracted malonyl-CoA-sensitive enzyme from rat liver mitochondria

1987 • 35 citations

Radiation inactivation analysis of oligomeric structure of the H,K-ATPase.

1988 • 31 citations

Evidence for distinct functional molecular sizes of carnitine palmitoyltransferases I and II in rat liver mitochondria

1988 • 29 citations

[13] Separation of right-side-out and inside-out submitochondrial particles by affinity chromatography on sepharose-cytochrome c

1979 • 29 citations

The apparent target size of rat brain benzodiazepine receptor, acetylcholinesterase, and pyruvate kinase is highly influenced by experimental conditions.

1988 • 27 citations

Hepatic carnitine palmitoyltransferase turnover and translation rates in fed, starved, streptozotocin-diabetic and diethylhexyl phthalate-treated rats

1987 • 27 citations

Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states

1985 • 25 citations

Molecular-size standards for use in radiation-inactivation studies on proteins

1986 • 17 citations

Separation of the protein-tyrosine kinase and phosphatidylinositol kinase activities of the human placental insulin receptor

1988 • 11 citations