Cloning, expression, pharmacology and regulation of a delayed rectifier K+ channel in mouse heart.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

1990 • 1,467 citations

Diversity and ubiquity of K channels

1988 • 1,342 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

1989 • 765 citations

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

1990 • 641 citations

Substrate specificity of protein kinase C

1986 • 521 citations

Cloning of a Membrane Protein That Induces a Slow Voltage-Gated Potassium Current

1988 • 511 citations

Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres

1969 • 462 citations

The surprising heart: a review of recent progress in cardiac electrophysiology.

1984 • 429 citations

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current

1982 • 421 citations

Intracellular Na+ activates a K+ channel in mammalian cardiac cells

1984 • 358 citations

Potassium Channels in Cardiac Cells Activated by Arachidonic Acid and Phospholipids

1989 • 329 citations

Regulation of a Heart Potassium Channel by Protein Kinase A and C

1988 • 317 citations

Molecular cloning and characterization of two voltage‐gated K ⁺ channel cDNAs from human ventricle

1991 • 245 citations

Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart.

1991 • 244 citations

Calcium‐activated transient outward current in calf cardiac Purkinje fibres.

1980 • 237 citations

How might the diversity of potassium channels be generated?

1990 • 191 citations

Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus.

1990 • 189 citations

Expression and Modulation of Voltage-Gated Calcium Channels After RNA Injection in Xenopus Oocytes

1986 • 174 citations

Current—voltage relations of Purkinje fibres in sodium‐deficient solutions

1963 • 173 citations

Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteins

1990 • 159 citations

Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library

1990 • 149 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

Purification and characterization of calcium/calmodulin-dependent protein kinase from rat brain

1984 • 147 citations

Molecular cloning and sequence analysis of human genomic DNA encoding A novel membrane protein which exhibits a slowly activating potassium channel activity

1989 • 142 citations

THE POTASSIUM CURRENT UNDERLYING DELAYED RECTIFICATION IN CAT VENTRICULAR MUSCLE

1978 • 132 citations

Estrogen induction of a small, putative K+ channel mRNA in rat uterus

1990 • 118 citations

Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked.

1988 • 117 citations

A three-step purification procedure for protein kinase C: Characterization of the purified enzyme

1987 • 107 citations

Regulation of heartbeat by G protein-coupled ion channels

1990 • 46 citations

Differences in myocardial alpha- and beta-adrenergic receptor numbers in different species

1983 • 37 citations

Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling

1988 • 29 citations

Regional expression of a MCD‐peptide and dendrotoxin I‐sensitive voltage‐dependent potassium channel in rat brain

1990 • 20 citations

Characterization of Gene Organization and Generation of Heterogeneous mRNA Species of Rat ISK Protein1

1990 • 16 citations

Molecular properties of potassium channels.

1989 • 15 citations

Potassium channels: Structure, classification, function and therapeutic potential

1990 • 10 citations