High Affinity Glutamate Transport in Rat Cortical Neurons in Culture

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

1997 • 1,715 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

Primary structure and functional characterization of a high-affinity glutamate transporter

1992 • 1,319 citations

Cloning and expression of a rat brain L-glutamate transporter

1992 • 1,230 citations

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

1992 • 1,185 citations

Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis

1992 • 1,170 citations

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

1995 • 1,124 citations

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1994 • 988 citations

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1997 • 909 citations

Nonvesicular release of neurotransmitter

1993 • 837 citations

Flux coupling in a neuronal glutamate transporter

1996 • 835 citations

Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1995 • 821 citations

[16] Protein determination in membrane and lipoprotein samples: Manual and automated procedures

1981 • 765 citations

Neuronal Regulation of Glutamate Transporter Subtype Expression in Astrocytes

1997 • 497 citations

Brain Glutamate Transporter Proteins Form Homomultimers

1996 • 471 citations

An [Na+ + K+]coupledl-glutamate transporter purified from rat brain is located in glial cell processes

1992 • 429 citations

Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex

1989 • 390 citations

Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase

1988 • 309 citations

Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer

1991 • 303 citations

Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture

1992 • 251 citations

Metabolic Trafficking between Neurons and Astrocytes: The Glutamate/Glutamine Cycle Revisited

1995 • 214 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

Differential Expression of Two Glial Glutamate Transporters in the Rat Brain: an In Situ Hybridization Study

1994 • 182 citations

Accumulation of Extracellular Glutamate by Inhibition of Its Uptake Is Not Sufficient for Inducing Neuronal Damage: An In Vivo Microdialysis Study

1995 • 154 citations

Pharmacologically distinct sodium-dependentl-[3H]glutamate transport processes in rat brain

1991 • 152 citations

Expression of the glutamate transporter GLT1 in neural cells of the rat central nervous system: Non-radioactive in situ hybridization and comparative immunocytochemistry

1996 • 150 citations

α‐Ketoglutarate and Malate Uptake and Metabolism by Synaptosomes: Further Evidence for an Astrocyte‐to‐Neuron Metabolic Shuttle

1984 • 143 citations

Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous d-aspartate

1993 • 138 citations

Subtypes of Sodium-Dependent High-Affinity L-[³H]Glutamate Transport Activity: Pharmacologic Specificity and Regulation by Sodium and Potassium

1993 • 136 citations

Heterogeneity of sodium‐dependent excitatory amino uptake mechanisms in rat brain

1986 • 133 citations

Comparison of Na+-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1).

1996 • 119 citations

Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus

1983 • 110 citations

Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: A semiquantitative electron microscopic study in rats

1990 • 107 citations

Inhibition of Glutamate Uptake with <scp>l</scp>‐trans‐Pyrrolidine‐2,4‐Dicarboxylate Potentiates Glutamate Toxicity in Primary Hippocampal Cultures

1993 • 100 citations

Accumulation of extracellular glutamate and neuronal death in astrocyte‐poor cortical cultures exposed to glutamine

1991 • 96 citations

Chapter 19: Ultrastructural immunocytochemical observations on the localization, metabolism and transport of glutamate in normal and ischemic brain tissue

1992 • 83 citations

Pharmacology of Sodium‐Dependent High‐Affinity <scp>l</scp>‐[³H]Glutamate Transport in Glial Cultures

1995 • 82 citations