Lipid-Associated Thermal Events in Biomembranes

Structural chemistry and molecular biology

1968 • 1,698 citations

Chilling Injury in Plants

1973 • 1,438 citations

Homeoviscous Adaptation—A Homeostatic Process that Regulates the Viscosity of Membrane Lipids in Escherichia coli

1974 • 1,433 citations

The function of sterols in membranes

1976 • 1,330 citations

Modern Aspects of the Vitreous State

1961 • 1,233 citations

Liquid Crystals and Ordered Fluids

1984 • 1,017 citations

Lateral phase separation in phospholipid membranes

1973 • 989 citations

Phase transitions in phospholipid vesicles Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol

1973 • 986 citations

Transmembrane control of the receptors on normal and tumor cells

1976 • 951 citations

Nature of the thermal pretransition of synthetic phospholipids: dimyristoyl- and dipalmitoyllecithin

1976 • 933 citations

Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry.

1976 • 927 citations

Studies on lecithin-cholesterol-water interactions by differential scanning calorimetry and X-ray diffraction

1968 • 891 citations

STRUCTURAL RELAXATION IN VITREOUS MATERIALS*

1976 • 821 citations

Thermal analysis of lipids, proteins and biological membranes a review and summary of some recent studies

1969 • 813 citations

EFFECT OF TEMPERATURE ON THE COMPOSITION OF FATTY ACIDS IN ESCHERICHIA COLI

1962 • 735 citations

Lateral diffusion of rhodopsin in the photoreceptor membrane

1974 • 658 citations

Melting and crystal structure

1950 • 544 citations

Calorimetric Studies of Dilute Aqueous Suspensions of Bilayers Formed from Synthetic l-α-Lecithins

1972 • 486 citations

Lipid phase transitions and phase diagrams II. Mixtures involving lipids

1977 • 465 citations

Evidence for Boundary Lipid in Membranes

1973 • 461 citations

Effects of proteins on the thermotropic phase transitions of phospholipid membranes

1975 • 444 citations

Rotational and Translational Diffusion in Membranes

1974 • 443 citations

Nuclear Magnetic Resonance in Biochemistry

1975 • 421 citations

Effect of sonication on the structure of lecithin bilayers

1972 • 421 citations

Methods in Membrane Biology

1978 • 417 citations

Lateral Diffusion in Spin-Labeled Phosphatidylcholine Multilayers

1972 • 415 citations

Melting and crystal structure

1966 • 408 citations

High-sensitivity scanning calorimetric study of mixtures of cholesterol with dimyristoyl- and dipalmitoylphosphatidylcholines

1978 • 406 citations

CALORIMETRIC EVIDENCE FOR THE LIQUID-CRYSTALLINE STATE OF LIPIDS IN A BIOMEMBRANE

1969 • 386 citations

Membrane molecular biology

1973 • 384 citations

The preferential interactions of cholesterol with different classes of phospholipids

1977 • 374 citations

Lipid phase transitions and phase diagrams I. Lipid phase transitions

1977 • 374 citations

Calcium-induced phase separations in phosphatidylserine-phosphatidylcholine membranes

1974 • 354 citations

Temperature-induced Phase Changes in Mitochondrial Membranes Detected by Spin Labeling

1971 • 347 citations

The preference of cholesterol for phosphatidylcholine in mixed phosphatidylcholine-phosphatidylethanolamine bilayers

1976 • 338 citations

THERMOTROPIC TRANSITIONS IN BIOMEMBRANES

1976 • 333 citations

Conjugated polyene fatty acids as fluorescent probes: synthetic phospholipid membrane studies

1977 • 328 citations

Crystalline-liquid crystaline phase transition of lipid model membranes. III. Structure of a steroid-lecithin system below and above the lipid-phase transition

1972 • 327 citations

Phase separations in phospholipid membranes

1975 • 324 citations

Phase transitions in cells, membranes, and lipids of Escherichia coli. Detection by fluorescent probes, light scattering, and dilatometry

1973 • 315 citations

Spin labels as enzyme substrates Heterogeneous lipid distribution in liver microsomal membranes

1973 • 303 citations

Lateral Phase Separations in Membrane Lipids and the Mechanism of Sugar Transport in Escherichia coli

1973 • 301 citations

The effect of chain length and lipid phase transitions on the selective permeability properties of liposomes

1975 • 290 citations

Correlation of In Vivo and In Vitro Phase Transitions of Membrane Lipids in Escherichia coli

1970 • 290 citations

The effect of cholesterol and epicholesterol incorporation on the permeability and on the phase transition of intact Acholeplasma laidlawii cell membranes and derived liposomes

1972 • 286 citations

Studies on the anomalous thermotropic behavior of aqueous dispersions of dipalmitoylphosphatidylcholine-cholesterol mixtures

1978 • 282 citations

PROTEIN-LIPID INTERACTIONS

1977 • 281 citations

The structure of Escherichia coli membranes studied by fluorescence measurements of lipid phase transitions

1973 • 281 citations

Lipid bilayer structure in the membrane of Mycoplasma laidlawii

1971 • 262 citations

Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes

1974 • 253 citations

The Planar Organization of Lecithin-Cholesterol Bilayers

1972 • 248 citations

Role of lipid-phase transitions in the regulation of the (sodium + potassium ion)-dependent adenosinetriphosphatase

1973 • 245 citations

Bacterial membranes and walls

1973 • 243 citations

Chemically induced lipid phase separation in model membranes containing charged lipids: A spin label study

1975 • 239 citations

Temperature-induced transitions of function and structure in sarcoplasmic reticulum membranes

1973 • 235 citations

The effect of the polar headgroup on the lipid-cholesterol interaction: A monolayer and differential scanning calorimetry study

1973 • 234 citations

Calorimetric Investigation of the Influence of Cholesterol on the Transition Properties of Bilayers Formed from Synthetic l-α-Lecithins in Aqueous Suspension

1972 • 228 citations

Evidence for phase boundary lipid. Permeability of tempo-choline into dimyristoylphosphatidylcholine vesicles at the phase transition

1976 • 227 citations

Temperature Control of Phospholipid Biosynthesis in Escherichia coli

1971 • 227 citations

Structure and function of the cell envelope of gram-negative bacteria.

1974 • 220 citations

Phase transitions of phospholipid bilayers and membranes of Acholeplasma laidlawii B visualized by freeze fracturing electron microscopy

1972 • 218 citations

Influence of fatty acid and sterol composition on the lipid phase transition and activity of membrane-bound enzymes in Acholeplasma laidlawii

1973 • 217 citations

Functional properties of biological membranes: A physical-chemical approach

1976 • 217 citations

Biogenesis of microbial transport systems: Evidence for coupled incorporation of newly synthesized lipids and proteins into membrane

1971 • 209 citations

A structural model for the cholesterol‐phosphatidylcholine complexes in bilayer membranes

1977 • 200 citations

Temperature- and light-dependent structural changes in rhodopsin-lipid membranes

1973 • 198 citations

Metabolic Alterations of Fatty Acids

1974 • 196 citations

The Molecular Organization of Lipids in the Membrane of Escherichia coli: Phase Transitions

1971 • 191 citations

The effect of alterations in fatty acid composition and cholesterol content on the nonelectrolyte permeability of Acholeplasma laidlawii B cells and derived liposomes

1973 • 184 citations

The effect of alterations in the physical state of the membrane lipids on the ability of Acholeplasma laidlawii B to grow at various temperatures

1974 • 182 citations

Liquid Crystals and Ordered Fluids

1970 • 180 citations

Characterization of the plasma membrane of Mycoplasma laidlawii. VII. Phase transitions of membrane lipids

1970 • 179 citations

The Effect of Phospholipid Fatty Acid Composition on Membranous Enzymes in Escherichia coli

1972 • 175 citations

Phase transitions in mammalian membranes

1972 • 174 citations

Molecular control of membrane properties during temperature acclimation. Fatty acid desaturase regulation of membrane fluidity in acclimating Tetrahymena cells

1976 • 171 citations

Relations between Structure and Function in Cytoplasmic Membrane Vesicles Isolated from an Escherichia coli Fatty‐Acid Auxotroph

1974 • 170 citations

Lipids containing trans-unsaturated fatty acids change the temperature characteristic of thiomethylgalactoside accumulation in Escherichia coli

1969 • 169 citations

Differences between conformations of lecithin and phosphatidylethanolamine polar groups and their effects on interactions of phospholipid bilayer membranes

1972 • 169 citations

Non-random distribution of cholesterol in phosphatidyl-choline bilayers

1974 • 166 citations

Cholesterol in mycoplasma membranes. Composition, ultrastructure and biological properties of membranes from Mycoplasma mycoides var. capri cells adapted to grow with low cholesterol concentrations

1973 • 158 citations

Mechanistic interpretation of the influence of lipid phase transitions on transport functions

1977 • 157 citations

Influence of Ca2+ and Mg2+ on the thermotropic behaviour and permeability properties of liposomes prepared from dimyristoyl phosphatidylglycerol and mixtures of dimyristoyl phosphatidylglycerol and dimyristoyl phosphatidylcholine

1975 • 156 citations

Motion of fatty acid spin labels in the plasma membrane of mycoplasma

1970 • 156 citations

Calorimetric Detection of a Membrane-Lipid Phase Transition in Living Cells

1970 • 154 citations

Tilted hydrocarbon chains of dipalmitoyl lecithin become perpendicular to the bilayer before melting

1975 • 154 citations

Isolation of a highly purified myelin protein

1971 • 150 citations

Brain lipid fatty acids and temperature acclimation

1964 • 147 citations

Lateral phase separations in Escherichia coli membranes

1974 • 145 citations

Lateral diffusion, protein mobility, and phase transitions in Escherichia coli membranes. Spin label study

1973 • 143 citations

The mycoplasmas.

1978 • 142 citations

Equilibrium Studies of Lecithin-Cholesterol Interactions

1978 • 140 citations

Cholesterol in mycoplasm membranes. Correlation of enzymic and transport activities with physical state of lipids in membranes of Mycoplasma mycoides var. capri adapted to grow with low cholesterol concentrations

1973 • 138 citations

The inter- and intra-molecular mixing of hydrocarbon chains in lecithin/water systems

1972 • 137 citations

Fatty-Acid Composition of Candida utilis as Affected by Growth Temperature and Dissolved-Oxygen Tension

1969 • 134 citations

Measurement of fast lateral diffusion of lipids in vesicles and in biological membranes by proton nuclear magnetic resonance

1973 • 133 citations

Thermotropic lipid clustering in tetrahymena membranes

1975 • 130 citations

Lipid- and temperature-dependent structural changes in Acholeplasma laidlawii cell membranes

1973 • 125 citations

Lipid phase separation induced by a hydrophobic protein in phosphatidylserine-phosphatidylcholine vesicles

1977 • 124 citations

Biogenesis of E. coli Membrane: Evidence for Randomization of Lipid Phase

1971 • 124 citations

The relationship between environmental temperature, cell growth and the fluidity and physical state of the membrane lipids in Bacillus stearothermophilus

1976 • 121 citations

Mycoplasma Membrane Lipids: Variations in Fatty Acid Composition

1969 • 120 citations

Analysis of the crystallization process in lecithin liposomes: A freeze-etch study

1973 • 119 citations

Composition of neutral lipids from erythrocytes of common mammals

1967 • 118 citations

Fragility of the permeability barrier of Escherichia coli

1972 • 118 citations

The stoichiometry and dynamics of lecithin-cholesterol clusters in bilayer membranes

1974 • 118 citations

Calorimetric and freeze fracture analysis of lipid phase transitions and lateral translational motion of intramembrane particles in mitochondrial membranes

1976 • 116 citations

Physical studies of membrane structure

1972 • 114 citations

Lipid phase transitions in cytoplasmic and outer membranes of Escherichia coli

1975 • 112 citations

Lipid molecular motion and enzyme activity in sarcoplasmic reticulum membrane

1976 • 112 citations

Cytochrome c induced lateral phase separation in a diphosphatidylglycerol-steroid spin-label model membrane

1976 • 112 citations

Fatty Acid Distribution in Bacterial Phospholipids. The Specificity of the Cyclopropane Synthetase Reaction^*

1964 • 112 citations

Interaction of a hydrophobic protein with liposomes evidence for particles seen in freeze fracture as being proteins

1974 • 109 citations

Membrane Structure: Spin Labeling and Freeze Etching of Mycoplasma laidlawii

1970 • 106 citations

Lateral Phase Separation of Lipids in Plasma Membranes: Effect of Temperature on the Mobility of Membrane Antigens

1974 • 104 citations

Molecular control of membrane properties during temperature acclimation. Membrane fluidity regulation of fatty acid desaturase action?

1976 • 104 citations

Lipid Bilayer Phase Transition: Density Measurements and Theory

1973 • 104 citations

Physical and Physiological Evidence for Two Phase Transitions in Cytoplasmic Membranes of Animal Cells

1974 • 101 citations

Differences in the interaction of inorganic and organic (hydrophobic) cations with phosphatidylserine membranes

1975 • 100 citations

Lipid mobility in Acholeplasma membranes using deuteron magnetic resonance

1972 • 100 citations

A dilatometric investigation of the effects of general anaesthetics, alcohols and hydrostatic pressure on the phase transition in smectic mesophases of dipalmitoyl phosphatidylcholine

1978 • 99 citations

Fluoroscence studies of chloropyll α incorporated into lipid mixtures, and the interpretation of “phase” diagrams

1975 • 99 citations

Physical studies of myelin I. Thermal analysis

1968 • 98 citations

Carbon-13 and proton nuclear magnetic resonance relaxation measurements of the lipids of sarcoplasmic reticulum membranes

1972 • 92 citations

The Mycoplasma Membrane

1975 • 90 citations

Modification of membrane lipid: physical properties in relation to fatty acid structure

1976 • 90 citations

Membrane molecular biology

1972 • 86 citations

Interaction of a purified hydrophobic protein from myelin with phospholipid membranes: Studies on ultrastructure, phase transitions and permeability

1975 • 85 citations

Spin-label studies on rat liver and heart plasma membranes: Do probe-probe interactions interfere with the measurement of membrane properties?

1977 • 82 citations

Coefficient of Volume Expansion for Petroleum Waxes and Pure n-Paraffins

1956 • 81 citations

The Antibacterial Activity of 3-Decynoyl-N-acetylcysteamine

1968 • 80 citations

The Architecture of Biological and Artificial Membranes as Visualized by Freeze Etching

1975 • 79 citations

On the Melting Points of Animal Fats in Cold Climates

1957 • 79 citations

Preparation and properties of vesicles of a purified myelin hydrophobic protein and phospholipid a spin label study

1976 • 78 citations

Use of a New Detector for X-ray Diffraction and Kinetics of the Ordering of the Lipids in E. coli Membranes and Model Systems

1972 • 78 citations

The phase rule

1966 • 76 citations

Molecular Association in Biological and Related Systems

1968 • 75 citations

Membranes as acceptors for palmitoyl CoA in fatty acid biosynthesis

1973 • 69 citations

The Effect of Temperature on Mitochondrial Membrane-linked Reactions

1974 • 68 citations

Mitochondrial d-β-Hydroxybutyrate Dehydrogenase

1973 • 66 citations

¹³C NMR spectra of acholeplasma membranes containing¹³C labelled phospholipids

1972 • 66 citations

Effects of structural defects in sonicated phospholipid vesicles on fusion and ion permeability

1975 • 65 citations

Correlation between Thermal Death and Membrane Fluidity in Bacillus stearothermophilus

1974 • 64 citations

Characterization of a low density cytoplasmic membrane subfraction isolated from Escherichia coli

1975 • 64 citations

Freeze-Fractured Acholeplasma laidlawii Membranes: Nature of Particles Observed

1973 • 63 citations

Molecular order in acholeplasma laidlawii membranes as determined by deuterium magnetic resonance of biosynthetically-incorporated specifically-labelled lipids

1975 • 63 citations

Membrane transitions in Gram-positive bacteria

1971 • 62 citations

The distribution of cholesterol in bilayers of phosphatidylcholines as visualized by freeze fracturing

1974 • 62 citations

The relationship between fatty acid structure and the positional distribution of esterified fatty acids in phosphatidyl glycerol from Mycoplasma laidlawii B

1970 • 60 citations

Lipid phase separations and protein distribution in membranes

1974 • 60 citations

Aliphatic chain transitions of phospholipid vesicles and phospholipid dispersions determined by polarization of fluoroscence

1973 • 58 citations

Factors affecting the acyl selectivities of acyltransferases in Escherichia coli.

1976 • 57 citations

Analysis of the defect structure of gel-phase lipid

1977 • 57 citations

Spin-Label Studies of Dynamics of Lipid Alkyl Chains in Biological Membranes: Role of Unsaturated Sites

1972 • 57 citations

Conjugated polyene fatty acids as fluorescent probes: biosynthetic incorporation of parinaric acid by Escherichia coli and studies of phase transitions

1977 • 56 citations

Control of Fatty‐Acid Biosynthesis by Long‐Chain Acyl CoAs and by Lipid Membranes

1974 • 53 citations

Correlations between fatty acid distribution in phospholipids and the temperature dependence of membrane physical state

1973 • 52 citations

Membrane assembly in Escherichia coli. 3. Abortive assembly of the lactose transport system in Escherichia coli

1973 • 52 citations

Correlations between fluorescence, X-ray diffraction, and physiological properties in cytoplasmic membrane vesicles isolated from Escherichia coli

1972 • 51 citations

Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma membranes

1973 • 51 citations

Effect of phase transition on the distribution of membrane-associated particles in microsomes

1976 • 49 citations

Nuclear magnetic resonance description of molecular motion and phase separations of cholesterol in lecithin dispersions.

1976 • 48 citations

Freeze etch morphology of outer membrane mutants of Escherichia coli K12

1976 • 48 citations

Dynamics of pyrene fluorescence in Escherichia coli membrane vesicles

1974 • 48 citations

Chloride diffusion from liposomes

1974 • 48 citations

Spin label evidence for the role of lysoglycerophosphatides in cellular membranes of hibernating mammals

1975 • 46 citations

A Density Label for Membranes

1970 • 43 citations

Thermal analysis of sarcoplasmic reticulum membranes

1974 • 42 citations

An automated differential scanning dilatometer

1975 • 41 citations

Divalent cations cooperatively stabilize close membrane contacts in myelin

1979 • 40 citations

Spray-freezing of liposomes

1973 • 39 citations

Role of lipids in the biosynthesis of the bacterial cell envelope.

1971 • 39 citations

Lipid and protein segregation in Escherichia coli membrane: morphological and structural study of different cytoplasmic membrane fractions.

1977 • 38 citations

The miscibility of dipalmitoyl phosphatidylcholine and cholesterol in monolayers

1976 • 36 citations

Randomization of membrane lipids in relation to transport system assembly in Escherichia coli

1976 • 35 citations

Control of fatty acid composition of Acholeplasma laidlawii membranes

1977 • 34 citations

The influence of lipid state on the planar distribution of membrane proteins in Acholeplasma laidlawii

1976 • 34 citations

Sulfide Solubilities in Alteration-Controlled Systems

1967 • 33 citations

Characterization of intermediate states in the ligation of hemoglobin

1973 • 32 citations

Molecular association in biological and related systems

1969 • 31 citations

Kinetics of phase equilibrium in a binary mixture of phospholipids

1976 • 28 citations

Effect of Temperature on the Distribution of Membrane Particles in Streptococcus faecalis as Seen by the Freeze-Fracture Technique

1974 • 28 citations

Temperature-mediated hyper-induction of fatty acid desaturating enzyme

1970 • 25 citations

Thermal techniques in biomembrane and lipoprotein research

1977 • 24 citations

Osmotic behaviour of acholeplasma laidlawii B cells with membrane lipids in liquid-crystalline and gel state

1975 • 22 citations

Variation in distribution of membrane particles in Acholeplasma laidlawii B with pH

1976 • 21 citations

A spin label study of E. coli membrane vesicles

1973 • 18 citations

Phase transitions in vertebrate and invertebrate photoreceptor membranes

1974 • 17 citations

�ber die Kunststoffe als unterk�hlte Fl�ssigkeiten

1954 • 14 citations

Organization of Yeast Mitochondrial Membranes: Fluidity and Phase Transition studied by Calorimetry and Spin-Label Methods

1974 • 11 citations