Biological Activities and Clinical Potential of Ebselen

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

A novel biologically active seleno-organic compound—1

1984 • 810 citations

A novel biologically active seleno-organic compound—II

1984 • 418 citations

The Liver: Biology and Pathobiology

1988 • 309 citations

Free radicals in biological systems—a review orientated to inflammatory processes

1987 • 235 citations

The two faces of selenium-deficiency and toxicity--are similar in animals and man.

1986 • 192 citations

Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51)

1988 • 160 citations

A novel biologically active selenoorganic compound—IV

1985 • 151 citations

Mechanism of the Catalytic Reduction of Hydroperoxides by Ebselen : A Selenium - 77 Nmr Study

1987 • 146 citations

Prevention of doxorubicin-induced killing of MCF-7 human breast cancer cells by oxygen radical scavengers and iron chelating agents

1986 • 143 citations

A novel biologically active seleno-organic compound—III

1984 • 140 citations

A novel biologically active seleno-organic compound—V

1985 • 131 citations

A novel biologically active seleno-organic compound—VI

1986 • 109 citations

An experimental model for hydrogen peroxide–induced tissue damage. Effects of a single inflammatory mediator on (peri)articular tissues

1986 • 89 citations

Ebselen reduces the formation of LTB4 in human and porcine leukocytes by isomerisation to its 5S, 12R-6-trans-isomer

1986 • 70 citations

A novel biologically active selenooorganic compound—VII

1988 • 65 citations

The anti-inflammatory activity of Ebselen but not thiols in experimental alveolitis and bronchiolitis

1988 • 53 citations

Inhibitory Effects of Ebselen on Lipid Peroxidation in Rat Liver Microsomes

1986 • 47 citations

Ebselen: a new approach to the inhibition of peroxide-dependent inflammation.

1987 • 44 citations

Inhibition of superoxide anion production in guinea pig polymorphonuclear leukocytes by a seleno-organic compound, ebselen.

1987 • 37 citations

Ebselen (PZ 51): A GSH-peroxidase-like organoselenium compound with anti-inflammatory activity.

1986 • 27 citations

Determination of the two major metabolites of ebselen in human plasma by high-performance liquid chromatography

1988 • 19 citations

Inhibition of gingivitis by topical application of ebselen and rosmarinic acid

1986 • 18 citations

Ebselen (PZ-51) Inhibits the Formation of Ischemic Brain Edema

1989 • 6 citations

INTERACTION OF EBSELEN WITH HEPATIC ARACHIDONATE METABOLISM<u>IN VIVO</u>

1988 • 5 citations