In vitro interaction of recombinant tumor necrosis factor alpha and all- trans-retinoic acid with normal and leukemic hematopoietic cells

Linear Statistical Inference and its Applications

1973 • 10,599 citations

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1984 • 6,841 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Linear Statistical Inference and Its Applications.

1975 • 3,726 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

1985 • 896 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

1981 • 566 citations

Acute Myelogenous Leukemia: A Human Cell Line Responsive to Colony-Stimulating Activity

1978 • 537 citations

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

1986 • 492 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

Phase I study of recombinant tumor necrosis factor in cancer patients.

1987 • 430 citations

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.

1985 • 394 citations

Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor.

1986 • 302 citations

Tumor necrosis factor and lymphotoxin induce differentiation of human myeloid cell lines in synergy with immune interferon.

1986 • 261 citations

Retinoic acid treatment of acute promyelocytic leukemia: in vitro and in vivo observations

1983 • 235 citations

Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells.

1982 • 224 citations

Identity of differentiation inducing factor and tumour necrosis factor

1986 • 181 citations

Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro*1

1982 • 178 citations

Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.

1986 • 155 citations

Human T lymphocyte cell line producing colony-stimulating activity

1978 • 147 citations

Phase I clinical trial of 13-cis-retinoic acid in myelodysplastic syndromes.

1983 • 147 citations

Probable in vivo induction of differentiation by retinoic acid of promyelocytes in acute promyelocytic leukaemia

1984 • 134 citations

Effect of recombinant human tumor necrosis factor on the colony growth of human leukemia progenitor cells and normal hematopoietic progenitor cells

1987 • 131 citations

Quantification and characterization of high‐affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

1986 • 110 citations

Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and Aspergillus pneumonia

1986 • 107 citations

Structure-activity relationships of a new series of retinoidal benzoic acid derivatives as measured by induction of differentiation of murine F9 teratocarcinoma cells and human HL-60 promyelocytic leukemia cells.

1983 • 105 citations

13-cis retinoic acid treatment for myelodysplastic syndromes.

1986 • 94 citations

In vitro action of tumor necrosis factor on myeloid leukemia cells

1987 • 91 citations

The role of 13 cis-retinoic acid in the remission induction of a patient with acute promyelocytic leukemia

1986 • 83 citations

Retinoids. Structure-function relationship in normal and leukemic hematopoiesis in vitro.

1986 • 69 citations

EFFECT OF 13-cis-RETINOIC ACID ON SURVIVAL OF PATIENTS WITH MYELODYSPLASTIC SYNDROME

1987 • 69 citations

Selective alterations in immunoregulatory lymphocyte subsets in early HIV (human T-lymphotropic virus type III/lymphadenopathy-associated virus) infection

1987 • 69 citations

Tumor necrosis factor: receptors on hematopoietic cells

1987 • 68 citations

A General Noninteractive Multiple Toxicity Model Including Probit, Logit, and Weibull Transformations

1985 • 56 citations

Phase I-II study of 13-cis-retinoic acid in myelodysplastic syndrome.

1985 • 54 citations

Retinoic acid cooperates with tumor necrosis factor and immune interferon in inducing differentiation and growth inhibition of the human promyelocytic leukemic cell line HL-60

1987 • 51 citations

Disappearance of cytogenetic abnormalities and clinical remission during therapy with 13-cis-retinoic acid in a patient with myelodysplastic syndrome: inhibition of growth of the patient's malignant monocytoid clone

1986 • 37 citations

Diversity of the effect of recombinant tumor necrosis factors alpha and beta on human myelogenous leukemia cell lines

1987 • 31 citations

Appearance of membrane-bound tyrosine kinase during differentiation of HL-60 leukemia cells by immune interferon and tumor necrosis factor

1986 • 23 citations

In-vitro effect of retinoic acid on normal and chronic myeloid leukemia granulopoiesis

1985 • 20 citations

Effect of retinoic acid on the clonal growth of childhood myeloid and lymphoid leukemias: a pediatric oncology group study.

1984 • 18 citations