Molecular and Antigenic Architecture of the Antiphagocytic Group A Streptococcal M Protein

Current Knowledge of Type-Specific M Antigens of Group A Streptococci

1962 • 793 citations

Complete nucleotide sequence of type 6 M protein of the group A Streptococcus. Repetitive structure and membrane anchor.

1986 • 364 citations

Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface.

1981 • 329 citations

PERSISTENCE OF TYPE-SPECIFIC ANTIBODIES IN MAN FOLLOWING INFECTION WITH GROUP A STREPTOCOCCI

1959 • 296 citations

Gene for an immunoglobulin-binding protein from a group G streptococcus

1986 • 249 citations

ELECTRON MICROSCOPIC STUDIES ON STREPTOCOCCI

1969 • 237 citations

Antigenic variation is associated with DNA rearrangements in a relapsing fever borrelia

1985 • 174 citations

Size variation in group A streptococcal M protein is generated by homologous recombination between intragenic repeats

1987 • 162 citations

Conversion of an M- group A streptococcus to M+ by transfer of a plasmid containing an M6 gene.

1986 • 141 citations

Tropomyosin-like seven residue periodicity in three immunologically distinct streptococal M proteins and its implications for the antiphagocytic property of the molecule.

1980 • 136 citations

Size variation of the M protein in group A streptococci.

1985 • 133 citations

Location of variable and conserved epitopes among the multiple serotypes of streptococcal M protein.

1985 • 113 citations

Presence of two distinct regions in the coiled-coil structure of the streptococcal Pep M5 protein: relationship to mammalian coiled-coil proteins and implications to its biological properties.

1985 • 103 citations

Streptococcal M6 protein expressed in Escherichia coli. Localization, purification, and comparison with streptococcal-derived M protein.

1984 • 102 citations

The complete amino acid sequence of a biologically active 197-residue fragment of M protein isolated from type 5 group A streptococci.

1984 • 100 citations

Immunochemical localization and amino acid sequences of crossreactive epitopes within the group A streptococcal M6 protein.

1986 • 86 citations

Relationship of M protein genes in group A streptococci.

1985 • 78 citations

Peptic Digestion of Streptococcal M Protein II. Extraction of M Antigen from Group A Streptococci With Pepsin

1974 • 66 citations

Expression of Streptococcal M Protein inEscherichia coli

1983 • 65 citations

Primary structure of protective antigens of type 24 streptococcal M protein.

1980 • 59 citations

Homologous regions within M protein genes in group A streptococci of different serotypes

1986 • 54 citations

Streptococcal M protein extracted by nonionic detergent. II. Analysis of the antibody response to the multiple antigenic determinants of the M-protein molecule.

1977 • 48 citations

Streptococcal M protein size mutants occur at high frequency within a single strain.

1986 • 47 citations

Repeating covalent structure and protective immunogenicity of native and synthetic polypeptide fragments of type 24 streptococcal M protein. Mapping of protective and nonprotective epitopes with monoclonal antibodies.

1983 • 46 citations

Requirements for the opsonic activity of human IgG directed to type 6 group A streptococci: net basic charge and intact Fc region.

1983 • 40 citations

Structural Difference Between Walls from Hemispherical Caps and Partial Septa of Bacillus subtilis

1973 • 34 citations

Acquisition of Group A streptococcal M protein antibodies

1985 • 27 citations

Streptococcal M protein extracted by nonionic detergent. III. Correlation between immunological cross-reactions and structural similarities with implications for antiphagocytosis.

1978 • 24 citations

Primary structure of streptococcal Pep M5 protein: Absence of extensive sequence repeats

1983 • 18 citations

Unimpaired function of human phagocytes in the presence of phagocytosis-resistant group A streptococci

1985 • 13 citations