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Hypervitaminosis A Induced Teratogenesis

Data up to Jan 2025

Published1979
Citations257
References147

Total Citations Per Year

Abstract

References (147)

Recommended Dietary Allowances.

1991 • 3,997 citations

Congenital Malformations

1953 • 1,096 citations

The morphology of various types of cell death in prenatal tissues

1973 • 716 citations

Nutrient Requirements of Laboratory Animals,

1995 • 702 citations

Recommended Dietary Allowances

1991 • 592 citations

Morphogenesis of malformations in hamsters caused by retinoic acid: Relation to dose and stage at treatment

1972 • 501 citations

Experimental Production of Congenital Malformations in Mammals by Metabolic Procedure

1959 • 383 citations

Swine in Biomedical Research

1966 • 353 citations

Excessive Intake of Vitamin A as a Cause of Congenital Anomalies in the Rat

1953 • 323 citations

Congenital Malformations. Notes and Comments

1972 • 291 citations

Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

1973 • 287 citations

CONGENITAL MALFORMATIONS

1973 • 260 citations

Experimental production of congenital malformations in strains of inbred mice by maternal treatment with hypervitaminosis A.

1961 • 235 citations

TERATOGENIC ACTIVITY OF RETINOIC ACID

1967 • 233 citations

CONGENITAL ANOMALIES IN THE RAT PRODUCED BY EXCESSIVE INTAKE OF VITAMIN A DURING PREGNANCY

1954 • 208 citations

VITAMIN A, CAROTENOIDS AND CELL FUNCTION

1965 • 198 citations

Teratology of the Central Nervous System

1969 • 156 citations

Morphogenesis of the malformations induced in rat embryos by maternal hypervitaminosis A.

1972 • 146 citations

Teratology of the Central Nervous System

1970 • 142 citations

Protides of the Biological Fluids

1975 • 130 citations

Nutrient Requirements of Rabbits

1966 • 128 citations

Mesodermal alterations induced by hypervitaminosis A

1966 • 106 citations

Excess vitamin A and development of the cerebral cortex

1967 • 101 citations

The use of in vitro procedures in teratology

1975 • 100 citations

Teratogenic effects of retinoic acid in pigtail monkeys (Macaca nemestrina) I. General features

1977 • 100 citations

Use of rhesus monkeys in teratological studies.

1971 • 91 citations

Effects of hypervitaminosis a on palate development in two strains of mice

1960 • 84 citations

Effect of vitamin A on development of the central nervous system

1966 • 80 citations

TERATOGENIC INTERACTION OF CHEMICAL AGENTS IN THE RAT

1964 • 75 citations

Environmental variables in oral disease

1967 • 75 citations

The ultrastructural effects of excess maternal vitamin A on the primitive streak stage rat embryo

1973 • 72 citations

Evaluation of the teratogenicity of drugs

1964 • 72 citations

Susceptible stages and abnormal morphogenesis in the developing mouse limb, analysed in organ culture after transplacental exposure to vitamin A (retinoic acid)

1974 • 71 citations

A learning impairment associated with maternal hypervitaminosis-A in rats

1972 • 70 citations

Somite necrosis and developmental malformations induced by vitamin A in the golden hamster

1965 • 68 citations

Hypervitaminosis A and congenital renal anomalies in a human infant.

1974 • 66 citations

Morphological and autoradiographic studies of cleft palate induced in rat embryos by maternal hypervitaminosis A.

1965 • 63 citations

THE TERATOGENIC EFFECTS OF HYPERVITAMINOSIS A UPON THE FACE AND MOUTH OF INBRED MICE*

1960 • 61 citations

Comparison of the effects of retinol and retinoic acid on postimplantation rat embryos in vitro

1977 • 61 citations

Some behavioral effects of maternal hypervitaminosis a in rats

1974 • 60 citations

Maternal vitamin A excess during the early fetal period: Effects on learning and development in the offspring

1973 • 59 citations

Studies of vitamin A‐induced teratogenesis: Effects on embryonic mesenchyme and epithelium, and on incorporation of H3‐thymidine

1968 • 58 citations

The effect of excess vitamin A on the development of rat embryos in culture

1974 • 55 citations

Parietal cephaloceles

1964 • 49 citations

The effects of vitamin A excess administered during the mid‐fetal period on learning and development in rat offspring

1974 • 46 citations

Teratogenic effects of hypervitaminosis A in the hamster and the guinea pig

1970 • 43 citations

Movement of palatine shelves in untreated and teratogen‐treated mouse embryos

1967 • 43 citations

Congenital Malformations of Upper Incisors in Exencephalic Mouse Embryos, Induced by Hypervitaminosis a I. Types and Frequency

1965 • 41 citations

Experimental Study of Teratogenic Effect of Emotional Stress in Rats

1960 • 40 citations

Variations in teratogenic response to hypervitaminosis A in three strains of the albino rat

1969 • 39 citations

Effect of Cortisone on the Incidence of Cleft-palate Induced by Experimental Hypervitaminosis-A

1957 • 38 citations

The pathogenesis of cleft palate. An animal study

1965 • 37 citations

The effects of various levels of dietary protein on retinoic acid‐induced teratogenicity in rats

1972 • 37 citations

Analysis of an Anomalous Oculodentofacial Pattern in Newborn Rats Produced by Maternal Hypervitaminosis A

1959 • 37 citations

The rapid detection of teratogenic activity.

1965 • 35 citations

Fusion of Upper Incisors at Bud or Cap Stage in Mouse Embryos with Exenceph-ALY Induced by Hypervitaminosis A

1965 • 33 citations

Influence of Cortisone on Teratogenic Effects of Hypervitaminosis-A

1957 • 32 citations

Congenital Malformations of Lower Incisors and Molars in Exencephalic Mouse Embryos, Induced by Hypervitaminosis A

1966 • 32 citations

Excessive intake of vitamin A during pregnancy as a cause of congenital anomalies in the rat.

1953 • 32 citations

Reduction in frequency of fetopathic effects of caffeine in mice by pretreatment with propranolol

1974 • 32 citations

Congenital Malformations of Upper Incisors in Exencephalic Mouse Embryos, Induced by Hypervitaminosis a II. Morphology of Fused Upper Incisors

1965 • 32 citations

Locomotory behavior of limb bud cells

1975 • 31 citations

Malformations of the Mouse Fetus Caused by Hypervitaminosis-A of the Mother During Pregnancy

1965 • 30 citations

Production of cleft palate with dexamethasone and hypervitaminosis A in rat embryos

1970 • 29 citations

Hypothalamic‐hypophysial adrenal and thyroid systems: Observations in fetal rats subjected to hypothalamic destruction, brain compression and hypervitaminosis A

1970 • 28 citations

Transplacental passage of label after administration of [3H]retinoic acid (vitamin A acid) to pregnant mice

1976 • 27 citations

Critical Time in the Hypothalamic Control of the Pituitary-Adrenal System in Fetal Rats: Observations in Fetuses Subjected to Hypervitaminosis A and Hypothalamic Destruction

1973 • 25 citations

Congenital Malformations of the Jaws and Related Structures in Exencephalic Mouse Embryos with Anomalous Molar Germs, Induced by Hypervitaminosis A

1966 • 22 citations

Fetomaternal Potassium Relations in the Fetal Rat on the Twentieth Day of Gestation

1975 • 21 citations

The mechanism of vitamin A induced teratogenesis

1964 • 21 citations

The role of sulfated mucopolysaccharides in cleft palate production

1970 • 20 citations

Tooth Germs in Non-Exencephalic Siblings of Mouse Embryos with Exencephaly Induced by Hyper Vitaminosis A

1967 • 20 citations

Relation of mandible growth to palate closure in mice

1974 • 20 citations

Influence of Uterine Position on the Response of the Mouse Embryo to the Teratogenic Effects of Hyper-vitaminosis-A

1961 • 18 citations

The effect of hypervitaminosis A on rat palatal development

1978 • 17 citations

Behavioral disturbances in rats receiving teratogenic agents antenatally

1969 • 16 citations

The localization of vitamin A in the pregnant rat by means of fluorescence microscopy

1972 • 16 citations

Observations on the Effect of Experimental Endocrine Procedures on the Teratogenic Action of Hypervitaminosis A in the Rat

1961 • 16 citations

VITAMIN A AND RAT EMBRYOS

1974 • 15 citations

Effect of Vitamin B Complex on the Teratogenic Activity of Hypervitaminosis A

1958 • 15 citations

Embryonic Uptake of S<sup>35</sup>-Sulfate: Change in Level Following Treatment with Some Teratogenic Agents

1968 • 15 citations

Congenital Malformations of the Central Nervous System

1963 • 15 citations

Nutrient Requirements of Dogs

1962 • 14 citations

Analysis of limb anomalies induced in vitro by vitamin A (retinol) in mice

1975 • 14 citations

Effect of vitamin A on the potentiality of rat palatal processes to fuse in vivo and in vitro.

1974 • 12 citations

Antenatal effect of pyrimethamine and vitamin a on behavior of the rat progeny

1971 • 12 citations

Vitamin A-induced anomalies in young rat embryos.

1973 • 12 citations

Insulin - Cortisone Relationship in Experimental Teratogenesis

1958 • 12 citations

The pathogenesis of cleft palate

1966 • 11 citations

Aspects of teratology of vitamin A acid (beta-all-trans retinoic acid).

1975 • 11 citations

Skullbase malformations in rat fetuses with hypervitaminosis A‐induced exencephaly

1973 • 10 citations

The role of amniotic fluid on the in-vitro palatal fusion of normal and vitamin A-treated rat foetuses

1977 • 10 citations

AN ELECTRON MICROSCOPIC STUDY OF THE EFFECTS OF HYPERVITAMINOSIS A ON THE MATERNAL-EMBRYONIC RELATIONSHIP OF THE RAT AT 8 DAYS OF PREGNANCY

1973 • 10 citations

Influence of 4-Methyl-2-thiouracil on the Teratogenic Activity of Hypervitaminosis-A

1958 • 10 citations

過剰ビタミンAのマウス肢芽形成に及ぼす影響 : I : 光学顕微鏡による観察

1974 • 9 citations

Mucin biosynthesis by chick and human oesophagus during ontogenetic metaplasia.

1970 • 9 citations

The Course of the Palatine Arteries During Secondary Palate Development in the Rat

1973 • 9 citations

Effects of three teratogens on development of arteries in the secondary palate in rats

1976 • 9 citations

Experimental Formation of Goiter in Exencephalic Fetal Rats Subjected to Maternal Hypervitaminosis A

1971 • 8 citations

Development of palate in normal murine embryo and influence of various agents on the conditions of palatine plates at different stages of embryonic development.

1968 • 8 citations

ANENCÉPHALIE EXPÉRIMENTALE CHEZ LA SOURIS ET COMPARAISONS AVEC L’ANENCÉPHALIE CHEZ L’HOMME

1960 • 8 citations

Dental Malformations in Rat Embryos with Exencephaly Induced by Hypervitaminosis A

1967 • 7 citations

Potency of Parenteral Vitamin A

1960 • 7 citations

Effects of ovariectomy and hypervitaminosis A on lysosomes of the rat conceptus

1969 • 7 citations

Malformations diverses du foetus de rat suivant les stades d'administration de vitamine A en excès.

1955 • 7 citations

Study of Closure of the Embryonic Rat Palate In Vitro with the Effects of Certain Chemicals

1969 • 6 citations

Teratogenically induced congenital aphakia

1964 • 6 citations

[Malformations of upper incisors in exencephalic mouse embryos, induced by hypervitaminosis A].

1967 • 6 citations

Potentiation of the teratogenic effect of vitamin A with exposure to low environmental temperature

1967 • 6 citations

Changes in incidence of the manifestation of anatomical variations of the vertebrae in the mouse fetus caused by X-radiation of maternal hypervitaminosis-A

1967 • 6 citations

Dental Anomalies in Mouse Embryos with Hydrocephalus Induced by Hypervitaminosis A

1967 • 5 citations

EFFECT OF HYPERVITAMINOSIS A ON THE FETUS OF SEVERAL SPECIES OF RODENTS, WITH SPECIAL REFERENCE TO MALFORMATION OF THE EXTREMITIES

1966 • 5 citations

Late effects of hypervitaminosis A in the rat; disturbance and retardation in the normal growth of offspring.

1958 • 4 citations

Dyschondrosteosis Produced in the Rat Fetus by Excessive Vitamin A

1974 • 4 citations

Normal/D1-trisomy mosaicism: A report of a case

1973 • 4 citations

[Hypervitaminosis A in pregnancy and malformations of the urinary tract in the fetus].

1975 • 4 citations

Morphogenesis of ophthalmic malformation of rats produced by A-hypervitaminosis.

1958 • 4 citations

過剰ビタミンAのマウス肢芽形成に及ぼす影響 II : 電子顕微鏡による観察

1974 • 4 citations

Study on micromelias in the mouse fetus caused by x-radiation, hypoxia, trypan blue injection of hypervitaminosis-A upon mother animals during pregnancy.

1964 • 4 citations

Lack of Hypertrophy of the Adrenal in Exencephalic Fetal Rats Subjected to Hypervitaminosis A and Then to Maternal Adrenalectomy

1971 • 3 citations

Changes in Facial Structures of Rats Caused by Supplements of Vitamin A and Lathyrus odoratus

1973 • 3 citations

Morphogenesis of experimental cleft palate due to excessive vitamin A.

1958 • 3 citations

Effects of urethan on the teratogenic action of hypervitaminosis A.

1965 • 3 citations

[Hypervitaminosis A and cleft palate].

1956 • 3 citations

二、三の実験動物胎仔に対する過剰vitaminAの影響 : とくに顔面耳殻症候群について

1966 • 3 citations

Malformations urinaires dans l'hypervitaminose A.

1957 • 3 citations

Embryological studies on the inner ear malformation of rats due to excessive vitamin A.

1960 • 3 citations

Strain differences in malformations of the extremities of the mouse fetus caused by x-radiation, hypoxia or hypervitaminosis-A of the mother during pregnancy.

1964 • 3 citations

Vitamin A過剰投与による催奇形作用におよぼす数種の薬剤の影響について : III. Riboflavine, Pyridoxineおよびfolic acidの影響について : 脂溶性ビタミンと奇形成立に関する研究

1968 • 3 citations

An embryological study on the abnormalities of the urinary tract system of rat due to excessive vitamin A.

1959 • 2 citations

Effects of the concurrent administrations of chondroitin sulfate with cortisone,vitamin A or noise stimulation on fetal development of the mouse.

1962 • 2 citations

Vitamin Aの過剰投与による催奇形作用におよぼす数種の薬剤の影響について : II.Vitamin B_ の影響について

1968 • 2 citations

Congenital malformation in rats due to hypervitaminosis A in combination with trypan blue and cortisone acetate.

1963 • 1 citations

[Cleft palate in embryos caused by large doses of vitamin A and cortisone administered to pregnant mice].

1965 • 1 citations

Morphogenetic study of congenital ocular malformations in rats, induced by excessive vitamin A, with special reference to exophthalmos.

1968 • 1 citations

The Infraseptal Nasal Glands in Mouse Embryos with Dental Malformations and Exencephaly Induced by Hypervitaminosis A

1967 • 1 citations

[Development of the palate in rats under normal conditions and with an experimental congenital cleft palate].

1966 • 1 citations

The tetatogenic effects of vitamin A acid in mice

1973 • 1 citations

Lack of maternal vitamin balance and embryonal malformations. 1. The effects of experimental 'A' avitaminosis or hypervitaminosis.

1967 • 1 citations

Effects of some drugs on experimental malformations due to hypervitaminosis A.

1965 • 1 citations

[Hypervitaminosis A in rat embryos. Autoradiographic studies on the teratogenic effect].

1972 • 1 citations

Morphogenesis of malformation due to excessive vitamin A. 4. Morphogenesis of congenital hydronephrosis and hydrouretter.

1959 • 1 citations

Effect of excess vitamin A on the occurrence of developmental defects in rats.

1964 • 1 citations

Hypervitaminosis a in pregnant mice of line C3HA and developmental anomalies of the palate and jaws in their offspring

1966 • 1 citations

Morphogenesis of Malformation due to Excessive Vitamin A (?) Morphogenesis of Cleft Palate and its Critical Phase

1959 • 1 citations

[Cephalic malformations caused by excess of vitamin A and morphological and pathogenetic aspects].

1958 • 1 citations

Deleted Work

1955 • 0 citations

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Hypervitaminosis A Induced Teratogenesis (1979) – CRC Critical Reviews in Toxicology | Metascience Observatory Explorer