Chapter 3: Production and Characterization of Mammalian Cells Reversibly Arrested in G1 by Growth in Isoleucine-Deficient Medium

An improved nutrient solution for diploid Chinese hamster and human cell lines

1963 • 890 citations

The initiation of cell division in a contact‐inhibited mammalian cell line

1965 • 807 citations

Growth and nucleic acid synthesis in synchronously dividing populations of HeLa cells

1963 • 780 citations

Cell Microfluorometry: A Method for Rapid Fluorescence Measurement

1969 • 457 citations

STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI

1954 • 406 citations

GENETICS OF SOMATIC MAMMALIAN CELLS

1958 • 402 citations

Life Cycle Analysis of Mammalian Cells

1963 • 360 citations

Hydroxyurea: Differential Lethal Effects on Cultured Mammalian Cells during the Cell Cycle

1965 • 347 citations

Studies with DNA-cellulose Chromatography. I. DNA-binding Proteins from Escherichia coli

1968 • 320 citations

REGULATION OF INITIATION OF DNA SYNTHESIS IN CHINESE HAMSTER CELLS

1970 • 271 citations

Effect of Dietary Tryptophan on Hepatic Polyribosomes and Protein Synthesis in Fasted Mice

1968 • 260 citations

Rapidly labeled, polyribosome-associated RNA having the properties of histone messenger.

1967 • 258 citations

Hydroxyurea: effects on Chinese hamster cells grown in culture.

1967 • 247 citations

A MICROPHOTOMETRIC STUDY OF THE SYNTHESES OF DESOXYRIBONUCLEIC ACID AND NUCLEAR HISTONE

1955 • 241 citations

Properties of mitotic cells prepared by mechanically shaking monolayer cultures of chinese hamster cells

1967 • 239 citations

Life Cycle Analysis of Mammalian Cells

1966 • 238 citations

CELL-CYCLE DEPENDENT DESQUAMATION OF HEPARAN SULFATE FROM THE CELL SURFACE

1972 • 197 citations

Reversible arrest of growth in G1 of an established fibroblast line (3T3)

1965 • 189 citations

Isoleucine-mediated regulation of genome repliction in various mammalian cell lines.

1971 • 188 citations

Analysis of the Life-Cycle in Mammalian Cells

1963 • 187 citations

The cell cycle : gene-enzyme interactions

1969 • 182 citations

Control of macromolecular synthesis in proliferating and resting syrian hamster cells in monolayer culture. I. Ribosome function

1971 • 165 citations

Biochemistry of Cell Division

1970 • 152 citations

REGULATION OF INITIATION OF DNA SYNTHESIS IN CHINESE HAMSTER CELLS

1970 • 149 citations

The metabolism of basic proteins in HeLa cell nuclei.

1966 • 142 citations

THE SYNTHESES OF TOTAL MACRONUCLEAR PROTEIN, HISTONE, AND DNA DURING THE CELL CYCLE IN EUPLOTES EURYSTOMUS

1966 • 142 citations

Correlation between cell enlargement and nucleic acid and protein content of hela cells in unbalanced growth produced by inhibitors of DNA synthesis

1967 • 138 citations

Fluctuations of DNA‐dependent RNA polymerase and synthesis of macromolecules during the growth cycle of Novikoff rat hepatoma cells in suspension culture

1969 • 136 citations

The influence of nutritional change on polyribosomes of the liver

1967 • 131 citations

Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression.

1972 • 127 citations

The metabolism of histone fractions

1968 • 125 citations

Cell Growth and Division

1969 • 122 citations

Phosphate Transport, Nucleotide Pools, and Ribonucleic Acid Synthesis in Growing and in Density-inhibited 3T3 Cells

1971 • 122 citations

Proteins binding to DNA and their Relation to Growth in Cultured Mammalian Cells

1971 • 117 citations

Quantity Production of Synchronized Mammalian Cells in Suspension Culture

1964 • 107 citations

Effects of cytosine arabinoside, daunomycin, mithramycin, azacytidine, adriamycin, and camptothecin on mammalian cell cycle traverse.

1972 • 106 citations

TIMING OF DNA SYNTHESIS IN THE MITOTIC CYCLE IN VITRO

1961 • 98 citations

The relation between DNA and protein synthesis in mouse fibroblasts

1965 • 97 citations

A method of measuring the degree of synchronization of cell populations

1961 • 97 citations

Regulation of Protein Synthesis Initiation in HeLa Cells Deprived of Single Essential Amino Acids

1971 • 96 citations

DNA Constancy in Heteroploidy and the Stem Line Theory of Tumors

1971 • 91 citations

Effect of tryptophan on polyribosomes and protein synthesis in liver

1971 • 84 citations

A METHOD FOR COMPARING EFFECTS OF DIFFERENT SYNCHRONIZING PROTOCOLS ON MAMMALIAN CELL CYCLE TRAVERSE

1972 • 84 citations

Life Cycle Analysis of Mammalian Cells

1964 • 82 citations

THE EFFECT OF THYMIDINE ON THE DURATION OF G1 IN CHINESE HAMSTER CELLS

1967 • 82 citations

The influence of tryptophan on hepatic polyribosomes and protein synthesis in fasted mice

1967 • 81 citations

Effects of isoleucine deficiency on nucleic acid and protein metabolism in cultured Chinese hamster cells. Continued ribonucleic acid and protein synthesis in the absence of deoxyribonucleic acid synthesis

1972 • 77 citations

Altered nucleic acid metabolism in human cell cultures infected with mycoplasma.

1968 • 74 citations

Control of macromolecular synthesis in proliferating and resting syrian hamster cells in monolayer culture. II. Ribosome complement in resting and early G₁ Cells

1971 • 73 citations

The metabolism of histone fractions. IV. Synthesis of histones during the G1-phase of the mammalian life cycle

1972 • 73 citations

Density Invariance of Cultured Chinese Hamster Cells with Stage of the Mitotic Cycle

1970 • 72 citations

Mycoplasmas in Tissue Culture

1966 • 68 citations

Change in pyrimidine deoxyribonucleoside metabolism in cell culture caused by Mycoplasma (PPLO) contamination

1963 • 68 citations

STUDIES ON THE MECHANISM OF ACTION OF PEDERINE

1968 • 68 citations

Inhibition of DNA synthesis by actinomycin D and cycloheximide in synchronized HeLa cells

1968 • 67 citations

RNA stability and protein synthesis in relation to the division of mammalian cells.

1966 • 65 citations

RNA SYNTHESIS IN CHINESE HAMSTER CELLS

1968 • 55 citations

The decay of synchronization of cell division

1964 • 52 citations

The Utilization of Proteins by Cultured Human Cells

1960 • 51 citations

A simple, rapid technique for determination of the effects of chemotherapeutic agents on mammalian cell-cycle traverse.

1972 • 49 citations

Isolation of low molecular weight, methylated ribonucleic acids from 10S to 30S particles of Chinese hamster cell fractions

1970 • 45 citations

Reversible arrest of Chinese hamster cells in G1 by partial deprivation of leucine

1972 • 44 citations

Possible role of histones in regulation of nucleic acid synthesis*1

1963 • 43 citations

Inhibitory effects of acetoxycycloheximide, puromycin, and pactamycin upon synthesis of protein and DNA in asynchronous populations of HeLa cells.

1966 • 42 citations

Modification of Amino-acid Concentrations Induced by Mycoplasmas in Cell Culture Medium

1971 • 41 citations

Cytogenetics of Cells in Culture

1964 • 40 citations

Influence of Acute Nutritional Stress on Polyribosomes and Protein Synthesis in Brain and Liver of Young Rats

1970 • 35 citations

The dependence of DNA synthesis on protein synthesis in HeLa S3 cells

1969 • 33 citations

METABOLISM OF ANIMAL CELLS INFECTED WITH MYCOPLASMA

1961 • 33 citations

Association of Aminoacyl Transferase II with Ribosomes of Intact HeLa Cells during Amino Acid Deprivation

1970 • 32 citations

Effects of Valine Deprivation on the Biosynthesis of Ribosomal and Messenger RNA in a Mammalian Cell Line (L 5178 Y)

1971 • 32 citations

Effects of deprivation of two essential amino acids on DNA synthesis in chinese hamster cells

1972 • 27 citations

Inhibition of cell division in L5178Y cells by arginine-degrading mycoplasmas: the role of arginine deiminase

1970 • 26 citations

Biochemical Balance and Synchronized Cell Cultures

1967 • 25 citations

Synchronized mammalian cells: An experimental test of a model for synchrony decay

1964 • 25 citations

Mycoplasma (PPLO) from Covertly Contaminated Tissue Cultures: Differences in Arginine Degradation Between Strains.

1964 • 21 citations

Rate of protein synthesis and polyribosome formation in the frog pancreas after fasting and feeding

1971 • 15 citations

Studies on Hepatic Polyribosomes and Protein Synthesis in Rats Force-fed a Protein-free Diet

1971 • 15 citations

Natural and induced synchronous cultures

1971 • 9 citations

The G1--S conversion: a target for cancer chemotherapy.

1969 • 5 citations

l-O-ethylthreonine—An antagonist of l-isoleucine

1969 • 5 citations

Effect of glutamine starvation on the ultrastructural organization of Chang's cultured cells

1968 • 2 citations