Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung.

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 • 842 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

1992 • 552 citations

Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues.

1990 • 533 citations

Unique Expression Pattern of the FGF Receptor 3 Gene during Mouse Organogenesis

1993 • 456 citations

breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.

1992 • 419 citations

Developmental expression of two murine fibroblast growth factor receptors, fig and bek

1991 • 397 citations

Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.

1992 • 321 citations

Differential Splicing in the Extracellular Region of Fibroblast Growth Factor Receptor 1 Generates Receptor Variants with Different Ligand-Binding Specificities

1992 • 321 citations

Transcriptional Elements from the Human SP-C Gene Direct Expression in the Primordial Respiratory Epithelium of Transgenic Mice

1993 • 299 citations

FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions

1994 • 275 citations

Mammalian lung development: Interactions in primordium formation and bronchial morphogenesis

1970 • 272 citations

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor.

1992 • 272 citations

Lung Development in the Mouse Embryo

1991 • 269 citations

Induction in vitro of tracheal buds by pulmonary mesenchyme grafted on tracheal epithelium

1962 • 251 citations

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

1993 • 240 citations

FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse

1991 • 232 citations

The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension.

1991 • 217 citations

3 Fibroblast Growth Factor and Its Involvement in Developmental Processes

1990 • 148 citations

Acidic fibroblast growth factor in the developing rat embryo.

1991 • 115 citations

A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity.

1992 • 112 citations

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.

1990 • 110 citations

Dominant-negative mutations of platelet-derived growth factor (PDGF) receptors. Inhibition of receptor function by ligand-dependent formation of heterodimers between PDGF alpha- and beta-receptors.

1993 • 39 citations

The influence of mesenchyme on the epithelial glycogen and budding activity in mouse embryonic lung developing in vitro

1971 • 13 citations